Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Tania Romacho"'
Autor:
Elisabeth Rohbeck, Corinna Niersmann, Karl Köhrer, Thorsten Wachtmeister, Michael Roden, Jürgen Eckel, Tania Romacho
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: We have previously shown that the novel positive allosteric modulator of the GABAA receptor, HK4, exerts hepatoprotective effects against lipotoxicity-induced apoptosis, DNA damage, inflammation and ER stress in vitro. This might be med
Externí odkaz:
https://doaj.org/article/4d6848ae40a74a2183711489576d449b
Autor:
Inés Valencia, Concepción Peiró, Óscar Lorenzo, Carlos F. Sánchez-Ferrer, Jürgen Eckel, Tania Romacho
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
COVID-19 outbreak, caused by severe acute respiratory syndrome (SARS)-CoV-2 coronavirus has become an urgent health and economic challenge. Diabetes is a risk factor for severity and mortality of COVID-19. Recent studies support that COVID-19 has eff
Externí odkaz:
https://doaj.org/article/d3ac0880b34d4aad890ef0484c46ca37
Autor:
Tania Romacho, Philipp Glosse, Isabel Richter, Manuela Elsen, Marieke H. Schoemaker, Eric A. van Tol, Jürgen Eckel
Publikováno v:
Nutrients, Vol 7, Iss 2, Pp 865-886 (2015)
Nutritional factors such as casein hydrolysates and long chain polyunsaturated fatty acids have been proposed to exert beneficial metabolic effects. We aimed to investigate how a casein hydrolysate (eCH) and long chain polyunsaturated fatty acids cou
Externí odkaz:
https://doaj.org/article/827fe743c5be4c12b8793ae2d4c26756
Autor:
Laura A Villalobos, Álvaro San Hipólito, Mariella Ramos-González, Elena Cercas, Susana Vallejo, Alejandra Romero, Tania Romacho, Raffaele Carraro, Carlos F Sánchez-Ferrer, Concepción Peiró
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Background and aims: Targeting inflammation is nowadays considered as a challenging pharmacological strategy to prevent or delay the development of vascular diseases. Angiotensin-(1-7) is a member of the renin-angiotensin system (RAS) that binds Mas
Externí odkaz:
https://doaj.org/article/ef511df028e447e4acb112b6e3b20f26
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Adipose tissue is acknowledged as an endocrine organ that releases bioactive factors termed adipokines. Visfatin was initially identified as a novel adipokine with insulin-mimetic properties in mice. This adipokine was identical to two previously des
Externí odkaz:
https://doaj.org/article/4cb744ea49974f97bf04a8e424c67ab3
Autor:
Tania Romacho, Laura A Villalobos, Elena Cercas, Raffaele Carraro, Carlos F Sánchez-Ferrer, Concepción Peiró
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78283 (2013)
BACKGROUND:Visfatin is a multifaceted adipokine whose circulating levels are enhanced in different metabolic diseases. Extracellular visfatin can exert various deleterious effects on vascular cells, including inflammation and proliferation. Limited e
Externí odkaz:
https://doaj.org/article/8cb2848045a04fb1b36126fd6195c7c1
Autor:
Silja Raschke, Manuela Elsen, Hans Gassenhuber, Mark Sommerfeld, Uwe Schwahn, Barbara Brockmann, Raphael Jung, Ulrik Wisløff, Arnt E Tjønna, Truls Raastad, Jostein Hallén, Frode Norheim, Christian A Drevon, Tania Romacho, Kristin Eckardt, Juergen Eckel
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73680 (2013)
Brown adipose tissue has gained interest as a potential target to treat obesity and metabolic diseases. Irisin is a newly identified hormone secreted from skeletal muscle enhancing browning of white fat cells, which improves systemic metabolism by in
Externí odkaz:
https://doaj.org/article/4e438abf22d641678b904f6d3ad82f55
Autor:
Susana Vallejo, Tania Romacho, Javier Angulo, Laura A Villalobos, Elena Cercas, Alejandra Leivas, Elena Bermejo, Raffaele Carraro, Carlos F Sánchez-Ferrer, Concepción Peiró
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27299 (2011)
Visfatin, also known as extracellular pre-B-cell colony-enhancing factor (PBEF) and nicotinamide phosphoribosyltransferase (Nampt), is an adipocytokine whose circulating levels are enhanced in metabolic disorders, such as type 2 diabetes mellitus and
Externí odkaz:
https://doaj.org/article/b96d134dd44842afad9df10b3fcdd148
Autor:
Verónica Azcutia, May Abu-Taha, Tania Romacho, Marta Vázquez-Bella, Nuria Matesanz, Francis W Luscinskas, Leocadio Rodríguez-Mañas, María Jesús Sanz, Carlos F Sánchez-Ferrer, Concepción Peiró
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10091 (2010)
BACKGROUND: Hyperglycemia is acknowledged as an independent risk factor for developing diabetes-associated atherosclerosis. At present, most therapeutic approaches are targeted at a tight glycemic control in diabetic patients, although this fails to
Externí odkaz:
https://doaj.org/article/871d7ca9d9614e8b8d5d21616e992cd9
Autor:
Inés Valencia, Susana Vallejo, Pilar Dongil, Alejandra Romero, Álvaro San Hipólito-Luengo, Licia Shamoon, María Posada, Damián García-Olmo, Raffaelle Carraro, Jorge D. Erusalimsky, Tania Romacho, Concepción Peiró, Carlos F. Sánchez-Ferrer
Publikováno v:
Hypertension. 79:1361-1373
Background: Abnormal accumulation of senescent cells in the vessel wall leads to a compromised vascular function contributing to vascular aging. Soluble DPP4 (dipeptidyl peptidase 4; sDPP4) secretion from visceral adipose tissue is enhanced in obesit