Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tania O. Crișan"'
Autor:
Orsolya I. Gaal, Ruiqi Liu, Dragoș Marginean, Medeea Badii, Georgiana Cabău, Ioana Hotea, Valentin Nica, Doina Colcear, HINT Consortium, Cristina Pamfil, Tony R. Merriman, Simona Rednic, Radu A. Popp, Tania O. Crișan, Leo A. B. Joosten
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Gout is a common autoinflammatory joint diseases characterized by deposition of monosodium urate (MSU) crystals which trigger an innate immune response mediated by inflammatory cytokines. IGF1R is one of the loci associated with both urate l
Externí odkaz:
https://doaj.org/article/972891c7991a4a1988a93549186a985c
Autor:
Georgiana Cabău, Medeea Badii, Andreea M. Mirea, Orsolya I. Gaal, Liesbeth van Emst, Radu A. Popp, Tania O. Crișan, Leo A. B. Joosten
Publikováno v:
Vaccines, Vol 12, Iss 7, p 736 (2024)
The mRNA vaccine against COVID-19 protects against severe disease by the induction of robust humoral and cellular responses. Recent studies have shown the capacity of some vaccines to induce enduring non-specific innate immune responses by the induct
Externí odkaz:
https://doaj.org/article/60953f5bbf2045ba8bb35236bd19efd1
Autor:
Georgiana Cabău, Orsolya Gaal, Medeea Badii, Valentin Nica, Andreea-Manuela Mirea, Ioana Hotea, Cristina Pamfil, Radu A. Popp, Mihai G. Netea, Simona Rednic, Tania O. Crișan, Leo A.B. Joosten
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107909- (2023)
Summary: Gout is an autoinflammatory disease triggered by a complex innate immune response to MSU crystals and inflammatory triggers. While hyperuricemia is an obligatory risk factor for the development of gout, the majority of individuals with hyper
Externí odkaz:
https://doaj.org/article/35ea8c8f24f54204ba68c7a8604f1c7b
Autor:
Dennis M. deGraaf, Lisa U. Teufel, Aline H. deNooijer, Adriaan J. vanGammeren, Antonius A. M. Ermens, Ildikó O. Gaál, Tania O. Crișan, Frank L. van deVeerdonk, Mihai G. Netea, Charles A. Dinarello, Leo A. B. Joosten, Rob J. W. Arts, the Radboudumc Center for Infectious Diseases COVID‐19 Study Group
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 11, Pp n/a-n/a (2022)
Abstract Introduction A major contributor to coronavirus disease 2019 (COVID‐19) progression and severity is a dysregulated innate and adaptive immune response. Interleukin‐38 (IL−38) is an IL‐1 family member with broad anti‐inflammatory pr
Externí odkaz:
https://doaj.org/article/316ee342c38842a0b2005fa7521bb057
Autor:
Nicholas A. Sumpter, Riku Takei, Murray Cadzow, Ruth K. G. Topless, Amanda J. Phipps‐Green, Rinki Murphy, Janak de Zoysa, Huti Watson, Muhammad Qasim, Alexa S. Lupi, Abhishek Abhishek, Mariano Andrés, Tania O. Crișan, Michael Doherty, Lennart Jacobsson, Matthijs Janssen, Tim L. Jansen, Leo A. B. Joosten, Meliha Kapetanovic, Frédéric Lioté, Hirotaka Matsuo, Geraldine M. McCarthy, Fernando Perez‐Ruiz, Philip Riches, Pascal Richette, Edward Roddy, Blanka Stiburkova, Alexander So, Anne‐Kathrin Tausche, Rosa J. Torres, Till Uhlig, Tanya J. Major, Lisa K. Stamp, Nicola Dalbeth, Hyon K. Choi, Ana I. Vazquez, Megan P. Leask, Richard J. Reynolds, Tony R. Merriman
Publikováno v:
Arthritis & Rheumatology, 75, 816-825
Arthritis & Rheumatology, 75, 5, pp. 816-825
Arthritis & Rheumatology, 75, 5, pp. 816-825
Item does not contain fulltext OBJECTIVE: To determine whether a gout polygenic risk score (PRS) is associated with age at gout onset and tophaceous disease in European, East Polynesian, and West Polynesian men and women with gout. METHODS: A 19-vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237258ce0f3468815af550aa92386a3d
https://hdl.handle.net/2066/292878
https://hdl.handle.net/2066/292878
Gout is a chronic disease of monosodium urate crystal deposition in the setting of hyperuricemia that typically presents with recurrent flares of acute inflammatory arthritis that occur due to innate immune response to deposited crystals. The molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1404de6af79972f194bfd955857f8fd3
https://doi.org/10.1101/2022.11.26.22281768
https://doi.org/10.1101/2022.11.26.22281768
Publikováno v:
Expert Review of Clinical Immunology, 18, 11, pp. 1125-1134
Expert Review of Clinical Immunology, 18, 1125-1134
Expert Review of Clinical Immunology, 18, 1125-1134
Contains fulltext : 286849.pdf (Publisher’s version ) (Open Access) INTRODUCTION: Trained Immunity (TI) refers to the long-term modulation of the innate immune response, based on previous interactions with microbes, microbial ligands, or endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b63e37976e7606a2f6a6a4c4808d90c
https://pubmed.ncbi.nlm.nih.gov/36062825
https://pubmed.ncbi.nlm.nih.gov/36062825
Autor:
Viola Klück, Leo A. B. Joosten, Alexander Hoischen, Charles A. Dinarello, Nicola Dalbeth, Rosanne C. van Deuren, Tony R. Merriman, T.L.Th.A. Jansen, Matthijs Janssen, Amara Shaukat, Christian Gilissen, Lorenzo Dagna, Peer Arts, Marloes Steehouwer, Lisa K. Stamp, Soohyun Kim, Stefan H. Lelieveld, Maartje C. P. Cleophas, Frank L. van de Veerdonk, Philip Riches, Elan Z. Eisenmesser, Tania O Crișan, Jennie Harré Hindmarsh, Mihai G. Netea, Maartje van de Vorst, Giulio Cavalli, Anne-Kathrin Tausche
Publikováno v:
Annals of the Rheumatic Diseases, 79, 536-544
Annals of the Rheumatic Diseases, 79, 4, pp. 536-544
Annals of the Rheumatic Diseases, 79, 4, pp. 536-544
ObjectiveGout is characterised by severe interleukin (IL)-1-mediated joint inflammation induced by monosodium urate crystals. Since IL-37 is a pivotal anti-inflammatory cytokine suppressing the activity of IL-1, we conducted genetic and functional st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfca4c0aa06a5599af1e0afe91e4523c
https://doi.org/10.1136/annrheumdis-2019-216233
https://doi.org/10.1136/annrheumdis-2019-216233
Publikováno v:
Joint Bone Spine, 89
Joint Bone Spine, 89, 4
Joint Bone Spine, 89, 4
Contains fulltext : 286865.pdf (Publisher’s version ) (Open Access) BACKGROUND: Rheumatic diseases include a variety of autoimmune and autoinflammatory conditions that are characterised by musculoskeletal involvement and systemic disease. Both inna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a9d2ef3db89bbab4a63d784b8468e0
https://hdl.handle.net/2066/286865
https://hdl.handle.net/2066/286865
Autor:
Boris Novakovic, Jelle Zwaag, Frank L. van de Veerdonk, Sebastian Weis, Rob J.W. Arts, Mariolina Bruno, Matthijs Kox, Tania O Crișan, Sita H. Vermeulen, Mihai G. Netea, Leo A. B. Joosten, Egbert Oosterwijk, Laszlo Groh, Anaisa V. Ferreira, Peter Pickkers, Jelmer H. van Puffelen, Elisa Jentho, Vera P. Mourits
Publikováno v:
Clinical & Translational Immunology, 10
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 2, Pp n/a-n/a (2021)
Clinical & Translational Immunology, 10, 2
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 2, Pp n/a-n/a (2021)
Clinical & Translational Immunology, 10, 2
Objectives Histone methyltransferase G9a, also known as Euchromatic Histone Lysine Methyltransferase 2 (EHMT2), mediates H3K9 methylation which is associated with transcriptional repression. It possesses immunomodulatory effects and is overexpressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdeec592d74011a9beebbc80a15ba83e
http://hdl.handle.net/2066/231611
http://hdl.handle.net/2066/231611