Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tania O. Alexson"'
Autor:
Tamara Holowacz, Tania O. Alexson, Brenda L. Coles, Bradley W. Doble, Kevin F. Kelly, James R. Woodgett, Derek Van Der Kooy
Publikováno v:
Biology Open, Vol 2, Iss 8, Pp 812-821 (2013)
Summary Neural stem cells (NSCs) can be obtained from a variety of sources, but not all NSCs exhibit the same characteristics. We have examined how the level of glycogen synthase kinase-3 activity regulates NSCs obtained from different sources: the m
Externí odkaz:
https://doaj.org/article/263313ab26584e0096e78d0970aa3343
Autor:
James R. Woodgett, Derek van der Kooy, Tamara Holowacz, Bradley W. Doble, Brenda L. K. Coles, Tania O. Alexson, Kevin F. Kelly
Publikováno v:
Biology Open
Biology Open, Vol 2, Iss 8, Pp 812-821 (2013)
Biology Open, Vol 2, Iss 8, Pp 812-821 (2013)
Summary Neural stem cells (NSCs) can be obtained from a variety of sources, but not all NSCs exhibit the same characteristics. We have examined how the level of glycogen synthase kinase-3 activity regulates NSCs obtained from different sources: the m
Publikováno v:
Developmental Neuroscience. 28:34-48
Recently, Notch signaling has been reported to underscore the ability of neural stem cells (NSCs) to self-renew. Utilizing mice deficient in presenilin-1(PS1), we asked whether the function of Notch signaling in NSC maintenance was conserved. At embr
Autor:
Vassiliki Nikoletopoulou, Vladimir A. Ruzhynsky, Jacqueline L. Vanderluit, Michael A. Rudnicki, Kerry L. Ferguson, Tania O. Alexson, Ruth S. Slack, Stephen M. McNamara, David S. Park, Maura H Parker
Publikováno v:
The Journal of Cell Biology
Here we show a novel function for Retinoblastoma family member, p107 in controlling stem cell expansion in the mammalian brain. Adult p107-null mice had elevated numbers of proliferating progenitor cells in their lateral ventricles. In vitro neurosph
Publikováno v:
The Journal of Neuroscience. 22:8653-8660
Nicotine, the primary psychoactive component of tobacco smoke, is known to possess potent rewarding and aversive stimulus properties. The mammalian ventral tegmental area (VTA) is involved importantly in the mediation of the motivational effects of n
Autor:
Tak W. Mak, Dorit B. Donoviel, Jeffrey S. Nye, Derek van der Kooy, Ronald A. Conlon, Vincent Tropepe, Andrew J. Elia, Alan Bernstein, Tania O. Alexson, Seiji Hitoshi
Publikováno v:
Genes & Development. 16:846-858
Neural stem cells, which exhibit self-renewal and multipotentiality, are generated in early embryonic brains and maintained throughout the lifespan. The mechanisms of their generation and maintenance are largely unknown. Here, we show that neural ste
Autor:
Cheryl Koscik, Shoji Tsuji, Susumu Kusunoki, Derek van der Kooy, Raewyn M. Seaberg, Tania O. Alexson, Seiji Hitoshi, Ichiro Kanazawa
Basic fibroblast growth factor (FGF2)-responsive definitive neural stem cells first appear in embryonic day 8.5 (E8.5) mouse embryos, but not in earlier embryos, although neural tissue exists at E7.5. Here, we demonstrate that leukemia inhibitory fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ec63eec5938c0fd9477dbc3440dce1
https://europepmc.org/articles/PMC517401/
https://europepmc.org/articles/PMC517401/