Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tania Ng"'
Autor:
Wei Jia, Phillip D. Yawman, Keyur M. Pandya, Kellie Sluga, Tania Ng, Dawen Kou, Karthik Nagapudi, Paul E. Luner, Aiden Zhu, Shawn Zhang, Hao Helen Hou
Publikováno v:
Pharmaceutical Research. 39:3137-3154
The purpose of this work is to evaluate the interrelationship of microstructure, properties, and dissolution performance for amorphous solid dispersions (ASDs) prepared using different methods.ASD of GDC-0810 (50% w/w) with HPMC-AS was prepared using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e731878341a27a4bc00f86ef93b51c5b
https://doi.org/10.1007/s11095-022-03308-9
https://doi.org/10.1007/s11095-022-03308-9
Autor:
Dawen Kou, Larry Wigman, Chen Zhang, Tania Ng, Matthew R. Durk, Hiuwing Yiu, Leslie W. Chinn, Matthew Janson, Joseph W. Lubach, Peter Yehl, Helen Winter, Chen Mao
Publikováno v:
Molecular Pharmaceutics. 15:1607-1617
In this study, a multipronged approach of in vitro experiments, in silico simulations, and in vivo studies was developed to evaluate the dissolution, supersaturation, precipitation, and absorption of three formulations of Compound-A, a BCS class 2 we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089b0b2c7a67f49cbf57aa2ec0c18685
https://doi.org/10.1021/acs.molpharmaceut.7b01143
https://doi.org/10.1021/acs.molpharmaceut.7b01143
Autor:
Preeti Patel, Chen Mao, Yannick Fischer, Hiuwing Yiu, Peter Yehl, Leslie W. Chinn, Larry Wigman, Sudharsan Dwaraknath, Daniel Nguyen, Dawen Kou, Tania Ng, Myeonghui Kim, Helen Winter, Matthew R. Durk
Publikováno v:
Molecular pharmaceutics. 14(10)
In this study, two dissolution models were developed to achieve in vitro-in vivo relationship for immediate release formulations of Compound-A, a poorly soluble weak base with pH-dependent solubility and low bioavailability in hypochlorhydric and ach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeaa9167d5a60b24853eae86478400a
https://pubmed.ncbi.nlm.nih.gov/28834434
https://pubmed.ncbi.nlm.nih.gov/28834434
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 37:1985-1998
Pinacol esters of boronic acids are widely used as starting materials in organic synthesis for Suzuki-Miyaura chemistry. The accurate analysis of these esters is complicated by competing hydrolysis to the corresponding boronic acids under typical RP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a39589c952009f3bd229e46e224001
https://doi.org/10.1080/10826076.2013.825856
https://doi.org/10.1080/10826076.2013.825856
Autor:
Sigal Balshine, Joanne L. Parrott, Tania Ng, Krista L. Gooderham, Mark E. McMaster, Joanna Y. Wilson, Julie R. Marentette, Chris M. Wood
Publikováno v:
Ecotoxicology and Environmental Safety. 73:1755-1764
The invasive round goby has a recognised role in transferring contaminants through foodwebs, but little work has been done on contaminant impacts on round gobies themselves. Here we present the first case study of contaminant biomarkers and subpopula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98abaac66701b008aa6112a83bc4276b
https://doi.org/10.1016/j.ecoenv.2010.06.007
https://doi.org/10.1016/j.ecoenv.2010.06.007
Publikováno v:
Marine Ecology Progress Series. 343:173-182
In this study we examined the latent effects of larval food limitation on the performance of juvenile Crepidula onyx under both laboratory and field conditions, and the possible mechanisms through which these latent effects were mediated. Larvae were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a768503050e90fb6674782a01f7999f
https://doi.org/10.3354/meps06928
https://doi.org/10.3354/meps06928
Publikováno v:
Inequality in Singapore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::523407233f8e671e46427381eb82aef8
https://doi.org/10.1142/9789814623841_0006
https://doi.org/10.1142/9789814623841_0006
Autor:
Tania Ng, Wen-Xiong Wang
Publikováno v:
Marine Ecology Progress Series. 299:193-204
The roles of subcellular distribution on silver (Ag) accumulation and elimination in the green mussel Perna viridis collected from 2 hydrographical zones (harbour vs. estuarine) in Hong Kong during 3 different seasons were investigated. Ag concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f52a4a349787cd8596624ba3e7f8a9a
https://doi.org/10.3354/meps299193
https://doi.org/10.3354/meps299193
Publikováno v:
Hong Kong University of Science and Technology
This study investigated whether the nature of the binding of the trace metals cadmium, silver and zinc accumulated by phytoplankton can affect their subsequent assimilation efficiencies (AE) in 3 filter-feeding benthic invertebrates, the green mussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc58e90aa6ce77f36da1040407ff5626
https://doi.org/10.3354/meps299179
https://doi.org/10.3354/meps299179
Publikováno v:
Aquatic toxicology (Amsterdam, Netherlands). 84(2)
We examined the relationship between Cd kinetics (uptake from solution and diet, and efflux), metallothionein turnover, and changes in the cytosolic distribution of accumulated Cd between protein fractions in the green mussel Perna viridis. We pre-ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da055217da26b04e065f19602df351df
https://pubmed.ncbi.nlm.nih.gov/17640747
https://pubmed.ncbi.nlm.nih.gov/17640747