Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Tania Maria Manieri"'
1
Akademický článek
Characterization of Neutralizing Human Anti-Tetanus Monoclonal Antibodies Produced by Stable Cell Lines
Autor: Tania Maria Manieri, Daniela Yumi Takata, Roselaine Campos Targino, Wagner Quintilio, João Victor Batalha-Carvalho, Camila Maria Lucia da Silva, Ana Maria Moro
Publikováno v: Pharmaceutics, Vol 14, Iss 10, p 1985 (2022)
Tetanus toxin (TeNT) is produced by C. tetani, a spore-forming bacillus broadly spread in the environment. Although an inexpensive and safe vaccine is available, tetanus persists because of a lack of booster shots and variable responses to vaccines d
Externí odkaz: https://doaj.org/article/f787a8fe8b5a409089776c79aa2a332b
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2
Akademický článek
Advances and challenges in therapeutic monoclonal antibodies drug development
Autor: Mariana Lopes dos Santos, Wagner Quintilio, Tania Maria Manieri, Lilian Rumi Tsuruta, Ana Maria Moro
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss spe (2018)
The use of serum containing polyclonal antibodies from animals immunized with toxins marked the beginning of the application of antibody-based therapy in late nineteenth century. Advances in basic research led to the development of the hybridoma tech
Externí odkaz: https://doaj.org/article/d2bb649d9534492598249ec4d73c40f8
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3
In silico Techniques for Prospecting and Characterizing Monoclonal Antibodies
Autor: Carolina G. Magalhaes, Tania Maria Manieri, João V. Batalha-Carvalho, Daniela Yumi Takata, Ana Maria Moro
In the past few years, improvement in computational approaches provided faster and less expensive outcomes on the identification, development, and optimization of monoclonal antibodies (mAbs). In silico methods, such as homology modeling, to predict
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c7c3a367db8d0a52b3cf77aab0050e
https://doi.org/10.5772/intechopen.94366
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4
Structural effects of stabilization and complexation of a zinc-deficient superoxide dismutase
Autor: Tania Maria Manieri, Rosanna Squitti, Giselle Cerchiaro, Stefano L. Sensi
Publikováno v: Heliyon
Heliyon, Vol 7, Iss 1, Pp e06100-(2021)
The activity of the erythrocyte Cu2,Zn2-superoxide dismutase (SOD1) is altered in Alzheimer's disease (AD) patients. These patients, compared to healthy subjects, exhibit low plasmatic zinc (Zn) levels in the presence of high plasmatic levels of copp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264da6817b993ada987d1400203fa777
https://pubmed.ncbi.nlm.nih.gov/33553758
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5
Natural and redesigned wasp venom peptides with selective antitumoral activity
Autor: Tania Maria Manieri, Marcelo D. T. Torres, Gislaine P. Andrade, Cibele Nicolaski Pedron, Roseli Hiromi Sato, Giselle Cerchiaro, Anderson Orzari Ribeiro, Cesar de la Fuente-Nunez, Vani Xavier Oliveira
Publikováno v: Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1693-1703 (2018)
About 1 in 8 U.S. women (≈12%) will develop invasive breast cancer over the course of their lifetime. Surgery, chemotherapy, radiotherapy, and hormone manipulation constitute the major treatment options for breast cancer. Here, we show that both a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ba7ce5ab40a0a7b99a1b6a66d3c9a5
https://doi.org/10.3762/bjoc.14.144
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6
Advances and challenges in therapeutic monoclonal antibodies drug development
Autor: Ana Maria Moro, Tania Maria Manieri, Lilian Rumi Tsuruta, Mariana Lopes dos Santos, Wagner Quintilio
Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. Especial (2018); e01007
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. Especial (2018); e01007
Brazilian Journal of Pharmaceutical Sciences; v. 54 n. Especial (2018); e01007
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss spe (2018)
The use of serum containing polyclonal antibodies from animals immunized with toxins marked the beginning of the application of antibody-based therapy in late nineteenth century. Advances in basic research led to the development of the hybridoma tech
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d470abd70f1b9cd28debf6c510d486
https://www.revistas.usp.br/bjps/article/view/153906
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7
Structural studies on SOD1 zinc site coordination with the new mutant T135S,K136E-SOD1
Autor: Tania Maria Manieri, Giselle Cerchiaro
Publikováno v: Free Radical Biology and Medicine. 128:S81-S82
Cu,Zn-Superoxide Dismutase (SOD1) has two metal ions on its active site: Cu which plays catalytic role and Zn that has a structural function. Cu ion is placed at SOD1 site through action of CCS (Copper chaperone for SOD) but Zn entrance in SOD1 is st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65e945cce0c1675d7b655f91c6ef9ffd
https://doi.org/10.1016/j.freeradbiomed.2018.10.183
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8
Synthesis of unsymmetrical phthalocyanine derivatives and their interaction with mammary MCF7 cells
Autor: Giselle Cerchiaro, Anderson Orzari Ribeiro, F.B. do Nascimento, Tania Maria Manieri
Publikováno v: Dyes and Pigments. 99:316-322
We report herein the synthesis and characterization of a group of unsymmetrical phthalocyanines modified with different combinations of hydrophobic and hydrophilic groups. Our results demonstrated that their solubility in polar media varies with the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17aaaa16bad933f199b6d1a5ee04113e
https://doi.org/10.1016/j.dyepig.2013.05.012
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10
Analytical methods for copper, zinc and iron quantification in mammalian cells
Autor: Tania Maria Manieri, Fernanda R. Bertuchi, Giselle Cerchiaro
Publikováno v: Metallomics. 5:1336
Highly complex analytical methods with different accuracies of measurement, reproducibilities and ease of analyses are currently being used to quantify metals in cellular media and tissue samples. In this review, the analytical methods commonly used
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb55574a618ce964ed5ede026840384
https://doi.org/10.1039/c3mt00136a
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