CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration

Autor: Nicole Keller, Christophe Combadière, Marianne Houssier, Mirna Sirinyan, Jean-Claude Jeanny, Charles Feumi, Laurent Jonet, Emilie Picard, Tania Ferroukhi, Mathieu P Rodero, Salomon-Yves Cohen, Dominique Chauvaud, Florian Sennlaub, Francine Behar-Cohen, Sylvain Chemtob, Philippe Deterre, Adeline Pezard, William Raoul, Sophie Lavalette, Patrice Debré

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2007, 117 (10), pp.2920-2928. ⟨10.1172/JCI31692⟩
Journal of Clinical Investigation, 2007, 117 (10), pp.2920-2928. ⟨10.1172/JCI31692⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2007, 117 (10), pp.2920-2928. 〈10.1172/JCI31692〉

International audience; The role of retinal microglial cells (MCs) in age-related macular degeneration (AMD) is unclear. Here we demonstrated that all retinal MCs express CX3C chemokine receptor 1 (CX3CR1) and that homozygosity for the CX3CR1 M280 al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9900aea6b760f2b1ee440d517104aeff
https://hal.archives-ouvertes.fr/hal-02998819