Formulation of water-soluble Buddleja globosa Hope extracts and characterization of their antimicrobial properties against Pseudomonas aeruginosa

Autor: Nicolas Araya, Martín A. Leiva-Soto, Maria V. Bruna, Almendra Castro-Munoz, Beatriz Behrend-Keim, Daniel Moraga-Espinoza, Tania F. Bahamondez-Canas

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Buddleja globosa Hope (BG) extracts are traditionally used to treat skin and gastric ulcers due to their healing properties. Non-aqueous solvents such as ethanol and DMSO are usually used to extract naturally occurring compounds. However, the cytotox

Externí odkaz: https://doaj.org/article/19796da078e149e3a7747bc2d48cc779

Current Status of In Vitro Models and Assays for Susceptibility Testing for Wound Biofilm Infections

Autor: Tania F. Bahamondez-Canas, Lara A. Heersema, Hugh D. C. Smyth

Publikováno v: Biomedicines, Vol 7, Iss 2, p 34 (2019)

Biofilm infections have gained recognition as an important therapeutic challenge in the last several decades due to their relationship with the chronicity of infectious diseases. Studies of novel therapeutic treatments targeting infections require th

Externí odkaz: https://doaj.org/article/4c00a9ac5e13489dbe8563faf5886ad3

In vivo Efficacy of a Dry Powder Formulation of Ciprofloxacin-Copper Complex in a Chronic Lung Infection Model of Bioluminescent Pseudomonas aeruginosa

Autor: Frederic Tewes, Hugh D. C. Smyth, Tania F. Bahamondez-Canas, Daniel Moraga-Espinoza, Alan B. Watts

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2020, 152, pp.201-217. ⟨10.1016/j.ejpb.2020.05.014⟩

International audience; A significant limitation of locally delivered treatments for chronic pulmonary infections is often the short residence time within the airways. Ciprofloxacin (CIP), for example, undergoes rapid absorption from the airway lumen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963b80c808f11be9c322d01ace952e15
https://www.hal.inserm.fr/inserm-02615177

Efficacy of Ciprofloxacin and Its Copper Complex against Pseudomonas aeruginosa Biofilms

Autor: Frederic Tewes, Hugh D. C. Smyth, Tania F. Bahamondez-Canas

Publikováno v: AAPS PharmSciTech
AAPS PharmSciTech, American Association of Pharmaceutical Scientists, 2019, 20 (5), pp.205. ⟨10.1208/s12249-019-1417-9⟩

International audience; A limitation of antibiotic treatments for P. aeruginosa (PA) chronic pulmonary infections is the reduced efficacy due to sub-therapeutic concentrations at the infection site and the development of biofilm. A novel approach to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82189a537d67bb984e373d5b1c300c1
https://doi.org/10.1208/s12249-019-1417-9

Essential Pharmaceutics

Autor: Ashlee D. Brunaugh, Daniel Moraga-Espinoza, Tania F. Bahamondez-Canas, Hugh D. C. Smyth, Robert O. Williams

Particularly in healthcare fields, there is a growing movement away from traditional lecture style courses towards active learning and team-based activities to improve retention of concepts and build higher level thinking through the application of c