Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tania C Felizardo"'
Autor:
Murtaza S Nagree, Tania C Felizardo, Mary L Faber, Jitka Rybova, C Anthony Rupar, S Ronan Foley, Maria Fuller, Daniel H Fowler, Jeffrey A Medin
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 4, Pp n/a-n/a (2022)
Abstract T cells are the current choice for many cell therapy applications. They are relatively easy to access, expand in culture, and genetically modify. Rapamycin‐conditioning ex vivo reprograms T cells, increasing their memory properties and cap
Externí odkaz:
https://doaj.org/article/0079c95dea544963be14b09273e298e6
Autor:
Gabrielle M Siegers, Tania C Felizardo, A Mark Mathieson, Yoko Kosaka, Xing-Hua Wang, Jeffrey A Medin, Armand Keating
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16700 (2011)
Gamma delta T cells (GDTc) lyse a variety of hematological and solid tumour cells in vitro and in vivo, and are thus promising candidates for cellular immunotherapy. We have developed a protocol to expand human GDTc in vitro, yielding highly cytotoxi
Externí odkaz:
https://doaj.org/article/b6ca6aecb7e84cf49698d16e04dfd348
Autor:
Shoba Amarnath, Arian Laurence, Nathaniel Zhu, Renato Cunha, Michael A. Eckhaus, Samuel Taylor, Jason E. Foley, Monalisa Ghosh, Tania C. Felizardo, Daniel H. Fowler
Publikováno v:
Haematologica, Vol 102, Iss 8 (2017)
CD4+ T-helper subsets drive autoimmune chronic graft-versus-host disease, a major complication after allogeneic bone marrow transplantation. However, it remains unclear how specific T-helper subsets contribute to chronic graft-versus-host disease. T-
Externí odkaz:
https://doaj.org/article/b3b576351c7c4b3e889e764c430b923a
Autor:
Bryan C. Au, Chyan-Jang Lee, Orlay Lopez-Perez, Warren Foltz, Tania C. Felizardo, James C.M. Wang, Ju Huang, Xin Fan, Melissa Madden, Alyssa Goldstein, David A. Jaffray, Badru Moloo, J. Andrea McCart, Jeffrey A. Medin
Publikováno v:
Biomedicines, Vol 4, Iss 1, p 6 (2016)
Anti-cancer immunotherapy is emerging from a nadir and demonstrating tangible benefits to patients. A variety of approaches are now employed. We are invoking antigen (Ag)-specific responses through direct injections of recombinant lentivectors (LVs)
Externí odkaz:
https://doaj.org/article/15278be89cf84754884d92928168d3dc
Autor:
Andrea E Filomeno, Rita A. Kandel, Tania C. Felizardo, Iran Rashedi, Elliot M. Berinstein, Armand Keating, Salomeh Jelveh, Xing-Hua Wang, Nara Yoon, Peter C. Ferguson, Jeffrey A. Medin, Paola A. Filomeno, Kyung-Phil Kim, Victor Dayan
Publikováno v:
Cytotherapy. 20:1001-1012
Background. Mesenchymal stromal cells (MSCs) promote wound healing, including after radiotherapy (RT) and surgery. The use of MSCs in regenerative medicine in the context of malignancy, such as to enhance wound healing post-RT/surgery in patients wit
Autor:
Parameswaran Hari, Lawrence G. Lum, Tania C. Felizardo, Binod Dhakal, Taylor Keaton, Daniel H. Fowler, Saurabh Chhabra, Anita D'Souza, Meera Mohan, Jee H Park
Publikováno v:
Blood. 138:2838-2838
Background Adoptive cell therapy of multiple myeloma is limited in part by T cell metabolic fitness, which can be enhanced by mTOR inhibition during ex vivo manufacturing. In a first-generation trial using ex vivo rapamycin, polyclonal autologous Th1
Autor:
Emma L. Woodward, William E. Paul, Jonathan Scott, Ming-an Sun, Nathaniel Zhu, Evelyn L. Martin, Yuefeng Huang, Samuel Taylor, Nick J. Reynolds, Daniel H. Fowler, Grace Mallett, M Elias, Tania C. Felizardo, Chaido Stathopoulou, Shoba Amarnath
Publikováno v:
Journal of Experimental Medicine. 214:1663-1678
Group 2 innate lymphoid cells (ILC-2s) regulate immune responses to pathogens and maintain tissue homeostasis in response to cytokines. Positive regulation of ILC-2s through ICOS has been recently elucidated. We demonstrate here that PD-1 is an impor
Autor:
Nathaniel Zhu, Samuel Taylor, Daniel H. Fowler, Renato Cunha, Shoba Amarnath, Monalisa Ghosh, Jason Foley, Tania C. Felizardo, Arian Laurence, Michael Eckhaus
Publikováno v:
Haematologica. 102:1446-1456
CD4+ T-helper subsets drive autoimmune chronic graft-versus-host disease, a major complication after allogeneic bone marrow transplantation. However, it remains unclear how specific T-helper subsets contribute to chronic graft-versus-host disease. T-
Publikováno v:
Cancer Research. 80:3233-3233
Introduction: Chimeric antigen receptor (CAR) engineered T cells have delivered remarkable anti-tumor effects. However, the potential for severe and life-threatening cytokine release syndrome (CRS) represents a therapeutic obstacle. CRS is in large p
Autor:
Shoba Amarnath, David Knight, Michael Eckhaus, Sanders I. van Kasteren, Ethan M. Shevach, Grace Mallett, Arunakumar Gangaplara, Lukasz P. Liniany, Francis A. Flomerfelt, Laura E. Edgington-Mitchell, Tania C. Felizardo, Colin Watts, Matthew Bogyo, Jinfang Zhu, Chaido Stathopoulou, Arian Laurence, Jonathan Martinez-Fabregas, Joshua J. Yim, Daniel H. Fowler, Rolando Berlinguer-Palmini, Leigh Samsel
Publikováno v:
Immunity, 49(2), 247-263.e7
CD4+ T cell differentiation into multiple T helper (Th) cell lineages is critical for optimal adaptive immune responses. This report identifies an intrinsic mechanism by which programmed death-1 receptor (PD-1) signaling imparted regulatory phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df105a93b49274717ce88480111c4c6e
https://hdl.handle.net/1887/80978
https://hdl.handle.net/1887/80978