Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Tania A. Jones"'
Autor:
Claire Vinel, Gabriel Rosser, Loredana Guglielmi, Myrianni Constantinou, Nicola Pomella, Xinyu Zhang, James R. Boot, Tania A. Jones, Thomas O. Millner, Anaelle A. Dumas, Vardhman Rakyan, Jeremy Rees, Jamie L. Thompson, Juho Vuononvirta, Suchita Nadkarni, Tedani El Assan, Natasha Aley, Yung-Yao Lin, Pentao Liu, Sven Nelander, Denise Sheer, Catherine L. R. Merry, Federica Marelli-Berg, Sebastian Brandner, Silvia Marino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The identification of patient-specific disease mechanisms and druggable targets is crucial for precision medicine in glioblastoma. Here, the authors show that comparing patients-matched glioma-initiating cells with neural stem cells enables the disco
Externí odkaz:
https://doaj.org/article/eef727b592d24a7697303fa96e18e608
Autor:
James R. Boot, Denise Sheer, Vardhman K. Rakyan, Catherine L.R. Merry, Claire Vinel, Sebastian Brandner, Sven Nelander, Yung-Yao Lin, Suchita Nadkarni, Tedani El Assan, Juho Vuononvirta, Thomas O Millner, Federica M. Marelli-Berg, Myrianni Constantinou, Loredana Guglielmi, Jamie L. Thompson, Xinyu Zhang, Gabriel Rosser, Tania A. Jones, Pentao Liu, Nicola Pomella, Anaelle A. Dumas, Jeremy Rees, Natasha Aley, Silvia Marino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications
Nature Communications
Epigenetic mechanisms which play an essential role in normal developmental processes, such as self-renewal and fate specification of neural stem cells (NSC) are also responsible for some of the changes in the glioblastoma (GBM) genome. Here we develo
Autor:
Lewis Woodward, Tania A Jones, Ankit Patel, Arran D Dokal, Thomas J Stone, Vinothini Rajeeve, Pedro R Cutillas, David T W Jones, Darren Hargrave, Thomas S Jacques, Denise Sheer
Publikováno v:
Neuro-Oncology. 24:i98-i98
Paediatric low-grade gliomas (pLGGs) are the most common type of childhood CNS tumours. Our study included pilocytic astrocytomas (PAs; KIAA1549:BRAF), glioneuronal tumours (GNTs; BRAFV600E) and location-matched controls. We initially performed kinas
Autor:
Mohammed S. Esa, David Young, George M. Elgallab, Mark S. Pearce, Tania L. Jones, Fraser Birrell, S.R. Gokul Krishnan, K.H. Christien Li
Publikováno v:
Bone. 152
Circulating microRNAs (c-miRs) show promise as biomarkers. This systematic review explores their potential association with age-related fracture/osteoporosis (OP), osteoarthritis (OA) and sarcopenia (SP), as well as cross-disease association. Most ov
Autor:
Palli Valapila Abdulrouf, Afif Ahmed, Basmah Albabtain, Moza AlHail, Muna Said Al-Ismail, Doua AlSaad, Muna AlSaadi, Filipa Alves da Costa, Ahmed Awaisu, Zaheer-Ud-Din Babar, Wasim Baqir, Ghada Bawazeer, Hayley J. Berry, Fraser N. Birrell, Ruth Buchan, Amy Chan, Ejaz Cheema, Rula Darwish, Wessam ElKassem, Kevin Flint, David Gardner, Hayley C. Gorton, Muhammad Abdul Hadi, Gil Hardy, Rabia Hussain, Sue Jones, Tania L. Jones, Saira Khan, Mohamed Izham Mohamed Ibrahim, Ahmed Moursi, Andrea Murphy, Claire O’Reilly, Theodoros Papasavvas, Ema Paulino, Teresa Isichei Pounds, Myroslava Sekh, Saba Shamim, Hadar Zaman, Andriy Zimenkovsky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7f0e179b745027ce0f62285fbcc5c6
https://doi.org/10.1016/b978-0-12-819378-5.09992-x
https://doi.org/10.1016/b978-0-12-819378-5.09992-x
Autor:
Johan Aarum, Shiron Rajendran, Andrea Malaspina, Gavin Giovannoni, Claudia P. Cabrera, Tania A. Jones, Rocco Adiutori, Denise Sheer, Michael R. Barnes
Publikováno v:
EMBO Reports
Most proteins in cell and tissue lysates are soluble. We show here that in lysate from human neurons, more than 1,300 proteins are maintained in a soluble and functional state by association with endogenous RNA, as degradation of RNA invariably leads
Autor:
Tania A Jones, Babatunji W Ogunkolade, Jaroslaw Szary, Johan Aarum, Muhammad A Mumin, Shyam Patel, Christopher A Pieri, Denise Sheer
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22399 (2011)
BORIS (CTCFL) is the paralog of CTCF (CCCTC-binding factor; NM_006565), a ubiquitously expressed DNA-binding protein with diverse roles in gene expression and chromatin organisation. BORIS and CTCF have virtually identical zinc finger domains, yet di
Externí odkaz:
https://doaj.org/article/d036b88b361b4ab183d6f47a2d1f9300
Autor:
Dorine A Bax, Suzanne E Little, Nathalie Gaspar, Lara Perryman, Lynley Marshall, Marta Viana-Pereira, Tania A Jones, Richard D Williams, Anita Grigoriadis, Gilles Vassal, Paul Workman, Denise Sheer, Rui M Reis, Andrew D J Pearson, Darren Hargrave, Chris Jones
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5209 (2009)
Although paediatric high grade gliomas resemble their adult counterparts in many ways, there appear to be distinct clinical and biological differences. One important factor hampering the development of new targeted therapies is the relative lack of c
Externí odkaz:
https://doaj.org/article/4d6745336d244c4e8dc3df8b58736e76
Autor:
Merell P. Billacura, Mark D. Turner, Graham A. Hitman, Kathryn Fair, Mark D. Berry, Tania A. Jones, Katie Hanna, Carl P. Nelson, Paul W. Caton, Michael J. Cripps, Babatunji W Ogunkolade, Robert Lowe, Sophie R. Sayers, Marta Bagnati
Publikováno v:
Biochemical pharmacology. 171
The worldwide prevalence of diabetes has reached 8.5% among adults, and this is characterised by elevated glucose concentrations and failing insulin secretion. Furthermore, most people with type 2 diabetes are either obese or overweight, with the ass
Autor:
Tania A. Jones, Pedro R. Cutillas, Lewis Woodward, Ankit Kumar Patel, Arran Dokal, Denise Sheer, Vinothini Rajeeve, Thomas J Stone, Thomas S. Jacques
Publikováno v:
Neuro-Oncology
Paediatric low-grade gliomas (pLGGs) constitute the largest group of childhood CNS tumours. They often cause significant disability and morbidity, despite their indolent growth and the good survival rate of patients. The most common genetic alteratio