Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tani-Ann Lee"'
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 3 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2934ed8c6f207f77eea17ceb99211e41
https://doi.org/10.1158/1535-7163.22486041.v1
https://doi.org/10.1158/1535-7163.22486041.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
AMG 386 is an investigational first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2. Although the therapeutic value of blocking Ang2 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fc85f3746b4b3881e43684fd11d58a
https://doi.org/10.1158/1535-7163.c.6532206.v1
https://doi.org/10.1158/1535-7163.c.6532206.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Methods, Figure Legends, and References from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f1f07abbb748f03b8d216b421c4503
https://doi.org/10.1158/1535-7163.22486035
https://doi.org/10.1158/1535-7163.22486035
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 1 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423e5ef205e090bf0f7e3fd936b186f7
https://doi.org/10.1158/1535-7163.22486047
https://doi.org/10.1158/1535-7163.22486047
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 2 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101a3ffc436ea2111d452cdf846600a7
https://doi.org/10.1158/1535-7163.22486044.v1
https://doi.org/10.1158/1535-7163.22486044.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 4 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0a5f009cdf18244a8365e54904ef38
https://doi.org/10.1158/1535-7163.22486038
https://doi.org/10.1158/1535-7163.22486038
Autor:
Deepak Yadav, Tani-Ann Lee, Brian Grot, Jay Singh, Emma Langley, Chen Li, Johnovan Kim, Jessica Zaid
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A742-A742
BackgroundAn emerging class of new protease-activatable prodrugs designed to enhance on-target activity and reduce off-target toxicity are being actively developed. Cytokines are complex immune mediators which display potent anti-tumor activity in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ce01a66aff5ba70a68bf58615e22750
https://doi.org/10.1136/jitc-2021-sitc2021.713
https://doi.org/10.1136/jitc-2021-sitc2021.713
Autor:
Deepak Yadav, Brian Grot, Johnavon Kim, Emma Langley, Phillip Kim, Jessica Zaid, Chen Li, Tani-Ann Lee
Publikováno v:
Cancer Research. 81:1745-1745
Recombinant IL-2 (aldesleukin) is a potent T cell proliferation and differentiation factor and is an approved immunotherapy for advanced melanoma and renal cell carcinoma. Despite the remarkable and durable remissions induced by IL-2 in a subset of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e15b7977b2fb5848d584fc078d2da63
https://doi.org/10.1158/1538-7445.am2021-1745
https://doi.org/10.1158/1538-7445.am2021-1745
Autor:
Sean Caenepeel, Stephen J. Kaufman, Juan Leal, Eric Hsu, Haejin Kim, Ji-Rong Sun, Juan Estrada, Isaac J. Hayward, Paul E. Hughes, Tani Ann Lee, Dongyin Yu, Brad Bolon, Russell C. Cattley, Beverly L. Falcón, Seog Joon Han, David Cordover, James M. McCabe, James Bready, Robert Radinsky, Tom Boone, Ling Wang, Luke Li, Anthony Ndifor, Richard Kendall, Linh T. Nguyen, Shao Xiong Wang, Grant Shimamoto, Eunju Hurh, Hosung Min, Mark Leo Michaels, Jonathan D. Oliner, Karen Rex, Angela Coxon, Donald M. McDonald
Publikováno v:
Molecular Cancer Therapeutics. 9:2641-2651
AMG 386 is an investigational first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2. Although the therapeutic value of blocking Ang2 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75911dd240dfae1bf1e5a0fa5ce1486
https://doi.org/10.1158/1535-7163.mct-10-0213
https://doi.org/10.1158/1535-7163.mct-10-0213
Autor:
Bruce Evans, John G. Allen, Matthew P. Bourbeau, Alexander M. Long, Xin Huang, Larry W Mann, Rick D Gaston, Paul S. Andrews, Peter Yakowec, Michael D. Bartberger, Randall W. Hungate, G. Erich Wohlhieter, Tani Ann Lee, Evelyn Yang, Stephen Schneider, Michael E Matison, Robert C. Gadwood, Andreas Reichelt, Klaus Michelsen, Dongyin Yu, Jonathan D. Oliner
Publikováno v:
Journal of medicinal chemistry. 52(22)
Tumor protein 53 (p53) is a critical regulator of cell cycle and apoptosis that is frequently disabled in human tumors. In many tumor types, p53 is deleted or mutated, but in others p53 is inactivated by overexpression or amplification of its negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8874429a3e1b775cb14bfdcd8cc3907f
https://pubmed.ncbi.nlm.nih.gov/19856920
https://pubmed.ncbi.nlm.nih.gov/19856920