Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Tang K. Tang"'
Autor:
Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh, Jhih-Jie Tsai, Kuo-Tai Yang, Yuh-Shan Jou, Teh-Ying Chou, Tang K. Tang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-8 (2024)
Externí odkaz:
https://doaj.org/article/0af0160c75144bc49abebe2e127ec4ae
Autor:
Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh, Jhih-Jie Tsai, Kuo-Tai Yang, Yuh-Shan Jou, Teh-Ying Chou, Tang K. Tang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-23 (2022)
Abstract Background Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps including epithelial–mesenchymal transition (EMT) process. Centrosome is an organelle that functions as the major microtubule org
Externí odkaz:
https://doaj.org/article/80eda9faf5454279a945279d4da5e4a8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The centrosome is composed of a pair of centrioles and serves as the major microtubule-organizing center (MTOC) in cells. Centrosome dysfunction has been linked to autosomal recessive primary microcephaly (MCPH), which is a rare human neurodevelopmen
Externí odkaz:
https://doaj.org/article/efad83d4448745d7adb4e310f0a81757
Autor:
En-Ju Chou, Tang K. Tang
Publikováno v:
Cells, Vol 10, Iss 6, p 1441 (2021)
Autosomal recessive primary microcephaly (MCPH) is a complex neurodevelopmental disorder characterized by a small brain size with mild to moderate intellectual disability. We previously demonstrated that human microcephaly RTTN played an important ro
Externí odkaz:
https://doaj.org/article/c1e479ee8e7846acb9cb84adf5f52559
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Mutations in many centriolar protein-encoding genes cause primary microcephaly. Here the authors show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building
Externí odkaz:
https://doaj.org/article/17908d7c695d4446b67c1c19166df732
Autor:
En-Ju Chou, Liang-Yi Hung, Chieh-Ju C. Tang, Wen-Bin Hsu, Hsin-Yi Wu, Pao-Chi Liao, Tang K. Tang
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2975-2987 (2016)
CPAP is required for centriole elongation during S/G2 phase, but the role of CPAP in mitosis is incompletely understood. Here, we show that CPAP maintains spindle pole integrity through its phosphorylation by Aurora-A during mitosis. Depletion of CPA
Externí odkaz:
https://doaj.org/article/1bb22a2249ab43efa6ec85328495d44f
Autor:
Kuo-Sheng Wu, Tang K. Tang
Publikováno v:
Biology Open, Vol 1, Iss 6, Pp 559-565 (2012)
Summary The primary cilium is a microtubule-based structure protruded from the basal body analogous to the centriole. CPAP (centrosomal P4.1-associated protein) has previously been reported to be a cell cycle-regulated protein that controls centriole
Externí odkaz:
https://doaj.org/article/dbb1ecf16cf1474b9031e6f8b62f2fd8
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
The meiotic generation of haploid gametes with equal contents of genetic material is important for sexual reproduction in mammals. Errors in the transmission of chromosomes during meiosis may lead to aneuploidy, which is the leading cause of miscarri
Externí odkaz:
https://doaj.org/article/de359b5c75ad4b11bf29cb671ccd4d77
Publikováno v:
Cilia: From Mechanisms to Disease-Part A ISBN: 9780443185861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f14b68fbb0ba9cf6a668202355166b6
https://doi.org/10.1016/bs.mcb.2022.07.021
https://doi.org/10.1016/bs.mcb.2022.07.021
Autor:
Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh, Jhih-Jie Tsai, Kuo-Tai Yang, Yuh-Shan Jou, Teh-Ying Chou, Tang K. Tang
Publikováno v:
Journal of biomedical science. 29(1)
Background Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps including epithelial–mesenchymal transition (EMT) process. Centrosome is an organelle that functions as the major microtubule organizing c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4117523ea81d68b4fe0ceda5d3c07107
https://pubmed.ncbi.nlm.nih.gov/35365182
https://pubmed.ncbi.nlm.nih.gov/35365182