Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tanenobu Harada"'
Autor:
Yuma Sugiyama, Tanenobu Harada, Yuka Kamei, Tomoharu Yasuda, Tomoji Mashimo, Akihiko Nishikimi, Mitsuo Maruyama
Publikováno v:
Experimental Gerontology, Vol 174, Iss , Pp 112130- (2023)
Senescent cells were recently shown to play a role in aging-related malfunctions and pathologies. This consensus has been facilitated by evidence from senolytic model mice capable of eliminating senescent cells in tissues using well-characterized sen
Externí odkaz:
https://doaj.org/article/17a093493d1b4f5ba33f2b79ac5669ca
Autor:
John C. Reed, Tanenobu Harada, Tadaaki Miyazaki, Daisuke Fujikura, Hong Mei Li, Taro Kawai, Shizou Akira, Atsushi Iwai, Jun Uehara
Publikováno v:
Cell Death & Differentiation. 16:1615-1621
Detachment of adherent epithelial cells from the extracellular matrix induces apoptosis, a process known as anoikis. We have shown that DAP3 is critical for anoikis induction. However, the mechanism for anoikis induction mediated by DAP3 is still unc
Autor:
Yoshinari Saito, Masashi Kanayama, Koji Suzuki, Tsuyoshi Asano, Toshimitsu Uede, Hong Mei Li, Tanenobu Harada, Yosuke Nakayama, Shigeyuki Kon, Akio Minami, Norimasa Iwasaki, Tadaaki Miyazaki, Daisuke Kurotaki, Koyu Ito, Junko Morimoto, Jun Uehara, Chiemi Kimura, Yutaka Matsui
Publikováno v:
The Journal of Immunology. 182:8015-8025
Osteopontin is critically involved in rheumatoid arthritis; however, the molecular cross-talk between osteopontin and joint cell components that leads to the inflammatory joint destruction is largely unknown. We found that not only osteopontin but al
Autor:
Ken-ichi Yagami, Fumihiro Sugiyama, Takayuki Ohshima, Yutaka Ueno, Hiroyoshi Iseki, Tanenobu Harada
Publikováno v:
Journal of Virology. 75:3965-3970
Rat parvovirus (RPV) is nonpathogenic in rats but causes persistent lymphocytotropic infection. We found that RPV was propagated in rat thymic lymphoma cell line C58(NT)D and induced apoptosis. Interestingly, a resistant subclone, C58(NT)D/R, from su
Publikováno v:
Apoptosis : an international journal on programmed cell death. 15(10)
Death associated protein 3 (DAP3) is known to be a highly conserved protein, and is responsible for regulating apoptosis induced by various stimuli. To understand the molecular mechanism of how DAP3 induces apoptosis, we performed yeast two-hybrid sc
Autor:
John C. Reed, Satoko Chiba, Masakazu Ito, Toshimitsu Uede, Tanenobu Harada, Daisuke Fujikura, Tadaaki Miyazaki, Franck Perez
Publikováno v:
Cell Death & Disease
Tumor necrosis factor-α (TNF-α) has important roles in several immunological events by regulating apoptosis and transcriptional activation of cytokine genes. Intracellular signaling mediated by TNF-receptor-type 1 (TNFR1) is constituted by two sequ