Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Tanel Mahlakõiv"'
Autor:
Manojkumar Gunasekaran, Andrea Difiglia, John Fitzgerald, Robert Hariri, William van der Touw, Tanel Mahlakõiv
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Influenza A virus (IAV) infections are a significant recurrent threat to public health and a significant burden on global economy, highlighting the need for developing more effective therapies. Natural killer (NK) cells play a pivotal role in the con
Externí odkaz:
https://doaj.org/article/0d02a4de68cb4a8899dccc132beb6d59
Autor:
Lin Kang, Xiaokui Zhang, Robert Hariri, Xuan Guo, Tanel Mahlakõiv, Shuyang He, Hemlata Rana, Andrea DiFiglia, John Fitzgerald, Irene Raitman, Valentina Rousseva, Salvatore Rotondo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/12f75f2ea07e42ca8c7ea5d55ea30152
Autor:
Srinivas Somanchi, Xiaokui Zhang, Robert Hariri, Xuan Guo, Tanel Mahlakõiv, Shuyang He, Hemlata Rana, Andrea DiFiglia, Joseph Gleason, William van der Touw
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Tumors often develop resistance to surveillance by endogenous immune cells, which include natural killer (NK) cells. Ex vivo activated and/or expanded NK cells demonstrate cytotoxicity against various tumor cells and are promising therapeu
Externí odkaz:
https://doaj.org/article/42582f6916a246feb88909a0c6c3ed33
Autor:
Daniel Schnepf, Pedro Hernandez, Tanel Mahlakõiv, Stefania Crotta, Meagan E Sullender, Stefan T Peterson, Annette Ohnemus, Camille Michiels, Ian Gentle, Laure Dumoutier, Celso A Reis, Andreas Diefenbach, Andreas Wack, Megan T Baldridge, Peter Staeheli
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0247738 (2021)
The commensal microbiota regulates susceptibility to enteric pathogens by fine-tuning mucosal innate immune responses, but how susceptibility to enteric viruses is shaped by the microbiota remains incompletely understood. Past reports have indicated
Externí odkaz:
https://doaj.org/article/d68b02450db24632b3ba2774fe30dfac
Autor:
Jonas Klinkhammer, Daniel Schnepf, Liang Ye, Marilena Schwaderlapp, Hans Henrik Gad, Rune Hartmann, Dominique Garcin, Tanel Mahlakõiv, Peter Staeheli
Publikováno v:
eLife, Vol 7 (2018)
Host factors restricting the transmission of respiratory viruses are poorly characterized. We analyzed the contribution of type I and type III interferon (IFN) using a mouse model in which the virus is selectively administered to the upper airways, m
Externí odkaz:
https://doaj.org/article/582c927dc0c04f1d916a7f6746b4ac4d
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004782 (2015)
Epithelial cells are a major port of entry for many viruses, but the molecular networks which protect barrier surfaces against viral infections are incompletely understood. Viral infections induce simultaneous production of type I (IFN-α/β) and typ
Externí odkaz:
https://doaj.org/article/658ca7961114403d82191c2cf1809045
Autor:
Pascale Hermant, Céline Demarez, Tanel Mahlakõiv, Peter Staeheli, Philip Meuleman, Thomas Michiels
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87906 (2014)
The type III interferon (IFN) receptor is preferentially expressed by epithelial cells. It is made of two subunits: IFNLR1, which is specific to IFN-lambda (IFN-λ) and IL10RB, which is shared by other cytokine receptors. Human hepatocytes express IF
Externí odkaz:
https://doaj.org/article/df4624e607d543ba8a605cb32f9f6d0c
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e96360 (2014)
Ebola virus (EBOV) is a highly virulent human pathogen. Recovery of infected patients is associated with efficient EBOV-specific immunoglobulin G (IgG) responses, whereas fatal outcome is associated with defective humoral immunity. As B-cell epitopes
Externí odkaz:
https://doaj.org/article/2f90c36c3330462d946ed4a24fa5d0aa
Autor:
Hélène Bierne, Laetitia Travier, Tanel Mahlakõiv, Ludovic Tailleux, Agathe Subtil, Alice Lebreton, Anupam Paliwal, Brigitte Gicquel, Peter Staeheli, Marc Lecuit, Pascale Cossart
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39080 (2012)
Bacterial infections trigger the expression of type I and II interferon genes but little is known about their effect on type III interferon (IFN-λ) genes, whose products play important roles in epithelial innate immunity against viruses. Here, we st
Externí odkaz:
https://doaj.org/article/1711231359ac456a81ad262309d5a270
Autor:
Pierre Becquart, Nadia Wauquier, Tanel Mahlakõiv, Dieudonné Nkoghe, Cindy Padilla, Marc Souris, Benjamin Ollomo, Jean-Paul Gonzalez, Xavier De Lamballerie, Mirdad Kazanji, Eric M Leroy
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9126 (2010)
To better understand Zaire ebolavirus (ZEBOV) circulation and transmission to humans, we conducted a large serological survey of rural populations in Gabon, a country characterized by both epidemic and non epidemic regions. The survey lasted three ye
Externí odkaz:
https://doaj.org/article/b86b5bb5197a4904b017d963bb2724a3