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pro vyhledávání: '"Tanaka, Simon"'
Autor:
Tanaka, Simon
Partial differential equations are a convenient way to describe reaction- advection-diffusion processes of signalling models. If only one cell type is present, and tissue dynamics can be neglected, the equations can be solved directly. However, in ca
Externí odkaz:
http://arxiv.org/abs/1509.08322
The simulation of morphogenetic problems requires the simultaneous and coupled simulation of signalling and tissue dynamics. A cellular resolution of the tissue domain is important to adequately describe the impact of cell-based events, such as cell
Externí odkaz:
http://arxiv.org/abs/1503.06726
Autor:
Tanaka, Simon, Iber, Dagmar
The development of long bones requires a sophisticated spatial organization of cellular signaling, proliferation, and differentiation programs. How such spatial organization emerges on the growing long bone domain is still unresolved. Based on the re
Externí odkaz:
http://arxiv.org/abs/1309.0226
Autor:
Tanaka, Simon, Iber, Dagmar
Microfluidics provides a powerful and versatile technology to accurately control spatial and temporal conditions for cell culturing and can therefore be used to study cellular responses to gradients. Here we use Lattice Boltzmann methods (LBM) to sol
Externí odkaz:
http://arxiv.org/abs/1307.4703
During embryonic development tissue morphogenesis and signaling are tightly coupled. It is therefore important to simulate both tissue morphogenesis and signaling simultaneously in in silico models of developmental processes. The resolution of the pr
Externí odkaz:
http://arxiv.org/abs/1305.5922
Organogenesis is a tightly regulated process that has been studied experimentally for decades. Computational models can help to integrate available knowledge and to better understand the underlying regulatory logic. We are currently studying mechanis
Externí odkaz:
http://arxiv.org/abs/1202.0428
Table S1. Average dimensions of the ACN pellets at day 7 of chondrogenic differentiation. Table S2. Parameters used in modeling ACNs. Figure S1. ACN regulates chondrogenic differentiation of human bone marrow derived MSC. Higher magnification images
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fceb930627b00035595a2ed6563af3
Publikováno v:
Stem Cell Research & Therapy
Sarem, M.; Otto, O.; Tanaka, S.; Shastri, V.P.: Cell number in mesenchymal stem cell aggregates dictates cell stiffness and chondrogenesis. In: Stem Cell Research and Therapy. Vol. 10 (2019) 10. (DOI: /10.1186/s13287-018-1103-y)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2019)
Stem Cell Research & Therapy, 10
Sarem, M.; Otto, O.; Tanaka, S.; Shastri, V.P.: Cell number in mesenchymal stem cell aggregates dictates cell stiffness and chondrogenesis. In: Stem Cell Research and Therapy. Vol. 10 (2019) 10. (DOI: /10.1186/s13287-018-1103-y)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2019)
Stem Cell Research & Therapy, 10
Background Although mesenchymal stem/stromal cell (MSC) chondrogenic differentiation has been thoroughly investigated, the rudiments for enhancing chondrogenesis have remained largely dependent on external cues. Focus to date has been on extrinsic va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a50372c89d38976fb8b85e582b6b2f71
https://pubmed.ncbi.nlm.nih.gov/30630531
https://pubmed.ncbi.nlm.nih.gov/30630531
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