Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tanaka, Remba"'
Autor:
Kim Bich Nguyen, Malte Roerden, Christopher J Copeland, Coralie M Backlund, Nory G Klop-Packel, Tanaka Remba, Byungji Kim, Nishant K Singh, Michael E Birnbaum, Darrell J Irvine, Stefani Spranger
Publikováno v:
eLife, Vol 12 (2023)
Cancer immunotherapies, in particular checkpoint blockade immunotherapy (CBT), can induce control of cancer growth, with a fraction of patients experiencing durable responses. However, the majority of patients currently do not respond to CBT and the
Externí odkaz:
https://doaj.org/article/9322e2334e694187a616ac7046594ee7
Autor:
Byungji, Kim, Ryan R, Hosn, Tanaka, Remba, Dongsoo, Yun, Na, Li, Wuhbet, Abraham, Mariane B, Melo, Manuel, Cortes, Bridget, Li, Yuebao, Zhang, Yizhou, Dong, Darrell J, Irvine
Publikováno v:
Journal of Controlled Release. 353:241-253
The recent clinical success of multiple mRNA-based SARS-CoV-2 vaccines has proven the potential of RNA formulated in lipid nanoparticles (LNPs) in humans, and products based on base-modified RNA, sequence-optimized RNA, and self-replicating RNAs form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a27996f51128028b14f168abfe074d
https://doi.org/10.1016/j.jconrel.2022.11.022
https://doi.org/10.1016/j.jconrel.2022.11.022
Autor:
Aereas Aung, Ang Cui, Laura Maiorino, Ava P. Amini, Justin R. Gregory, Maurice Bukenya, Yiming Zhang, Heya Lee, Christopher A. Cottrell, Duncan M. Morgan, Murillo Silva, Heikyung Suh, Jesse D. Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M. Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, J. Christopher Love, Phillip Huyett, Douglas S. Kwon, Nir Hacohen, William R. Schief, Sangeeta N. Bhatia, Darrell J. Irvine
Publikováno v:
Science
The structural integrity of vaccine antigens is critical to the generation of protective antibody responses, but the impact of protease activity on vaccination in vivo is poorly understood. We characterized protease activity in lymph nodes and found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c651a6c41babaa4eff4f551a3120dc0e
https://doi.org/10.1126/science.abn8934
https://doi.org/10.1126/science.abn8934
Autor:
Kim B. Nguyen, Christopher J. Copeland, Coralie M. Backlund, Nory G. Klop-Packel, Tanaka Remba, Byungji Kim, Nishant K. Singh, Michael E. Birnbaum, Darrell J. Irvine, Stefani Spranger
Cancer immunotherapies, in particular checkpoint blockade immunotherapy (CBT), can induce control of cancer growth, with a fraction of patients experiencing durable responses. However, the majority of patients currently do not respond to CBT and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63515caff9fa98eab7f4ec5687ea64dc
https://doi.org/10.1101/2022.12.16.520773
https://doi.org/10.1101/2022.12.16.520773
Autor:
Heya Lee, Tanaka Remba, Parastoo Amlashi, Aereas Aung, Shuhao Xiao, Maurice Bukenya, Nir Hacohen, Sangeeta N. Bhatia, William R. Schief, Heikyung Suh, Douglas S. Kwon, Darrell J. Irvine, Ava P. Soleimany, Josetta Adams, Wuhbet Abraham, Christopher A. Cottrell, Murillo Silva, Leah Michelle Froehle, Phillip Huyett, Jesse D. Kirkpatrick, Ang Cui
SUMMARYThe structural integrity of vaccine antigens is critical, as antigen degradation in vivo could eliminate neutralizing epitopes and create competing B cell responses against irrelevant breakdown products. Using FRET imaging and imaging zymograp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7930a06b7fb3a80444f781dc611a704
https://doi.org/10.1101/2021.11.15.468669
https://doi.org/10.1101/2021.11.15.468669