Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Tanaji T Talele"'
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164227 (2016)
Bacterial infections present a serious challenge to healthcare practitioners due to the emergence of resistance to numerous conventional antibacterial drugs. Therefore, new bacterial targets and new antimicrobials are unmet medical needs. Rhodanine d
Externí odkaz:
https://doaj.org/article/b9d73e2d8cf948aab22299826671ee23
Autor:
Eduardo E Chufan, Khyati Kapoor, Hong-May Sim, Satyakam Singh, Tanaji T Talele, Stewart R Durell, Suresh V Ambudkar
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82463 (2013)
P-glycoprotein (Pgp, ABCB1) is an ATP-Binding Cassette (ABC) transporter that is associated with the development of multidrug resistance in cancer cells. Pgp transports a variety of chemically dissimilar amphipathic compounds using the energy from AT
Externí odkaz:
https://doaj.org/article/b57c78459fd54df1ba5568083ff1929c
Autor:
Dan He, Xiao-qin Zhao, Xing-gui Chen, Yi Fang, Satyakam Singh, Tanaji T Talele, Hui-juan Qiu, Yong-ju Liang, Xiao-kun Wang, Guo-qing Zhang, Zhe-sheng Chen, Li-wu Fu
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54181 (2013)
ATP-binding-cassette family membrane proteins play an important role in multidrug resistance. In this study, we investigated BIRB796, an orally active inhibitor of p38 mitogen-activated protein kinase, reversed MDR induced by ABCB1, ABCG2 and ABCC1.
Externí odkaz:
https://doaj.org/article/3c26397f57974182b21481b99906be2e
Autor:
Pei-Rong Ding, Amit K Tiwari, Shinobu Ohnuma, Jeferson W K K Lee, Xin An, Chun-Ling Dai, Qi-Si Lu, Satyakam Singh, Dong-Hua Yang, Tanaji T Talele, Suresh V Ambudkar, Zhe-Sheng Chen
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19329 (2011)
One of the major causes of chemotherapy failure in cancer treatment is multidrug resistance (MDR) which is mediated by the ABCB1/P-glycoprotein. Previously, through the use of an extensive screening process, we found that vardenafil, a phosphodiester
Externí odkaz:
https://doaj.org/article/cb95b23e897c4dfcb741737a73a9522f
Autor:
Mao Wang, Alex G. Gauthier, Thomas P. Kennedy, Haichao Wang, Uday Kiran Velagapudi, Tanaji T. Talele, Mosi Lin, Jiaqi Wu, LeeAnne Daley, Xiaojing Yang, Vivek Patel, Sung Soo Mun, Charles R. Ashby, Lin L. Mantell
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-17 (2021)
Abstract Background High mobility group box 1 protein (HMGB1) is an alarmin following its release by immune cells upon cellular activation or stress. High levels of extracellular HMGB1 play a critical role in impairing the clearance of invading pulmo
Externí odkaz:
https://doaj.org/article/751de7d9c34541a58841dbf2cd260d81
Autor:
Mao Wang, Alex G. Gauthier, Thomas P. Kennedy, Haichao Wang, Uday Kiran Velagapudi, Tanaji T. Talele, Mosi Lin, Jiaqi Wu, LeeAnne Daley, Xiaojing Yang, Vivek Patel, Sung Soo Mun, Charles R. Ashby, Lin L. Mantell
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/3c5379945c7b4e43ac2c2ebcb8e9854e
Autor:
Zhe-Sheng Chen, Li-Wu Fu, Tanaji T. Talele, Suresh V. Ambudkar, Ioana Abraham, Xingxiang Peng, Susan E. Bates, In-Wha Kim, Satyakam Singh, Robert W. Robey, Suneet Shukla, Amit K. Tiwari, Zhi Shi
Supplementary Table 1 from Sildenafil Reverses ABCB1- and ABCG2-Mediated Chemotherapeutic Drug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cca71fb55cf3bb45fccac7779db71c
https://doi.org/10.1158/0008-5472.22389446.v1
https://doi.org/10.1158/0008-5472.22389446.v1
Autor:
Zhe-Sheng Chen, Li-Wu Fu, Tanaji T. Talele, Suresh V. Ambudkar, Ioana Abraham, Xingxiang Peng, Susan E. Bates, In-Wha Kim, Satyakam Singh, Robert W. Robey, Suneet Shukla, Amit K. Tiwari, Zhi Shi
Supplementary Figure 1 from Sildenafil Reverses ABCB1- and ABCG2-Mediated Chemotherapeutic Drug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702eef8c12ce834279c31522577e7d30
https://doi.org/10.1158/0008-5472.22389449.v1
https://doi.org/10.1158/0008-5472.22389449.v1
Autor:
Ashif I. Bhuiyan, Athena H. Choi, Sarbani Ghoshal, Ugochi A. Adiele, Dibyendu Dana, Jun Yong Choi, Karl R. Fath, Tanaji T. Talele, Sanjai K. Pathak
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 88:129288
Autor:
Haichao Wang, Mosi Lin, Uday Kiran Velagapudi, Lee-Anne Daley, Sung Soo Mun, Alex G. Gauthier, Xiaojing Yang, Jiaqi Wu, Charles R. Ashby, Lin L. Mantell, Mao Wang, Vivek Patel, Tanaji T. Talele, Thomas P. Kennedy
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-17 (2021)
Molecular Medicine
Molecular Medicine
Background High mobility group box 1 protein (HMGB1) is an alarmin following its release by immune cells upon cellular activation or stress. High levels of extracellular HMGB1 play a critical role in impairing the clearance of invading pulmonary path