Výsledky vyhledávání - "Tan-Jun Tong"

Paradoxical effects of cellular senescence-inhibited gene involved in hepatocellular carcinoma migration and proliferation by ERK pathway and mesenchymal-like markers

Autor: Shi-Hua Hu, Siqi Wang, Ji-ye Zhu, Zhao Li, Dingbao Chen, Tan-Jun Tong, Qian Cheng

Publikováno v: OncoTargets and therapy

Qian Cheng,1 Tan-jun Tong,2 Zhao Li,1 Shi-hua Hu,1 Ding-bao Chen,1 Si-qi Wang,1 Ji-ye Zhu1 1Peking University Institute of Organ Transplantation, Peking University Center of Liver Cancer Diagnosis and Treatment, Beijing Key Surgical Basic Research La

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9068ad8e1c6e69a7e2a4fd2d4d08d42
https://doi.org/10.2147/ott.s188449

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Real-Time Detection Reveals Responsive Cotranscriptional Formation of Persistent Intramolecular DNA and Intermolecular DNA:RNA Hybrid G-Quadruplexes Stabilized by R-Loop

Autor: Yang Zhao, Tan-jun Tong, Yu-hua Hao, Zong-yu Zhang, Jia-yu Zhang, Zheng Tan

Publikováno v: Analytical Chemistry. 89:6036-6042

G-quadruplex (GQ) structures are implicated in important physiological and pathological processes. Millions of GQ-forming motifs are enriched near transcription start sites (TSSs) of animal genes. Transcription can induce the formation of GQs, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b66f31fcc70513e3777f4aaa0025b9
https://doi.org/10.1021/acs.analchem.7b00625

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Two isomers of HDTIC isolated from Astragali Radix decrease the expression of p16 in 2BS cells

Autor: Zongyu Zhang, Tan-jun Tong, Pei-chang Wang, Jian Zhang

Publikováno v: Chinese Medical Journal. 121:231-235

Background Astragali Radix, the root of Astragalus membranceus (Fish) Bunge Var. mongholicus (Bge), is a crude drug considered as one of the effective traditional Chinese anti-ageing material. The two isomers of 4-hydroxy-5-hydroxymethyl-[1, 3] dioxo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effb3c543a1fa0efbbb24e9f095cd10f
https://doi.org/10.1097/00029330-200802010-00009

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Optimization of reporter gene assay: several factors influencing detection of promoter activity

Autor: Tan-Jun Tong, Zongyu Zhang, Mo Weng, Lixiang Xue

Publikováno v: Chinese Medical Journal. 120:965-969

Background Promoter analysis is currently applied to detect the expression of the targeted gene in studies of signal transduction and transcriptional regulation. As a reporter gene, luciferase plays an important role and has been used widely in the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac1a42c2098d5f0f74b0e441bab3d747
https://doi.org/10.1097/00029330-200706010-00005

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[Comparison of Southern blotting and Real-time PCR in measuring telomere shortening]

Autor: Ling-yun, Gao, Guo-dong, Li, Tan-jun, Tong

Publikováno v: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. 45(2)

To analyze and compare the performances of two telomere measurement methods (digoxigenin-labeled Southern blot and Real-time PCR) in cellular senescence research.Genomic DNA extracted from normal human fibroblasts (2BS) of different population doubli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbba7528eddc72edb7189d048dffee4d
https://pubmed.ncbi.nlm.nih.gov/23591355

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The two isomers of HDTIC compounds from Astragali Radix slow down telomere shortening rate via attenuating oxidative stress and increasing DNA repair ability in human fetal lung diploid fibroblast cells

Autor: Tan-jun Tong, Zongyu Zhang, Peichang Wang, Xinwen Liu, Ying Sun

Publikováno v: DNA and cell biology. 29(1)

4-Hydroxy-5-hydroxymethyl-[1,3]dioxolan-2,6'-spirane-5',6',7',8'-tetrahydro-indolizine-3'-carbaldehyde (HDTIC)-1 and HDTIC-2 are two isomers extracted from Astragalus membranaceus (Fisch) Bunge Var. mongholicus (Bge) Hsiao. Our previous study had dem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7c9e3b1adf2f4292464915c4cf23de
https://pubmed.ncbi.nlm.nih.gov/19839736

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