Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families

Autor: Mohammad Ahangari, Amanda E. Gentry, Irish Schizophrenia Genomics Consortium, Tan-Hoang Nguyen, Robert Kirkpatrick, Brian C. Verrelli, Silviu-Alin Bacanu, Kenneth S. Kendler, Bradley T. Webb, Brien P. Riley

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-7 (2022)

Abstract Multiplex families have higher recurrence risk of schizophrenia compared to the families of sporadic cases, but the source of this increased recurrence risk is unknown. We used schizophrenia genome-wide association study data (N = 156,509) t

Externí odkaz: https://doaj.org/article/5711992aff624d3a91ae0297fe59c844

APPLYING MACHINE LEARNING FOR ENVIRONMENTAL FACTOR PREDICTION ON DESIGNING IOT APPLIED HYDROPONIC SYSTEM.

Autor: Van-Tinh NGUYEN¹ tinh.nguyenvan@hust.edu.vn, Tan-Hoang NGUYEN¹, Ngoc-Kien NGUYEN¹

Publikováno v: INMATEH - Agricultural Engineering. 2024, Vol. 73 Issue 2, p658-667. 10p.

Genome-wide analysis of schizophrenia and multiple sclerosis identifies shared genomic loci with mixed direction of effects

Autor: Mohammad Ahangari, Elif Everest, Tan-Hoang Nguyen, Brian C. Verrelli, Bradley T. Webb, Silviu-Alin Bacanu, Eda Tahir Turanli, Brien P. Riley

Publikováno v: Brain, Behavior, and Immunity. 104:183-190

Common genetic variants identified in genome-wide association studies (GWAS) show varying degrees of genetic pleiotropy across complex human disorders. Clinical studies of schizophrenia (SCZ) suggest that in addition to neuropsychiatric symptoms, pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ed4be2e940462731744220fae06835
https://doi.org/10.1016/j.bbi.2022.06.007

Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families

Autor: Silviu-Alin Bacanu, Tan-Hoang Nguyen, Bradley T. Webb, Brien P. Riley, Kenneth S. Kendler, Amanda Elswick Gentry, Robert M. Kirkpatrick, Brian C. Verrelli, Mohammad Ahangari

Publikováno v: Ahangari, M, Gentry, A E, Nguyen, T-H, Kirkpatrick, R, Verrelli, B C, Bacanu, S-A, Kendler, K S, Webb, B T, Riley, B P & Irish Schizophrenia Genomics Consortium 2022, ' Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families ', Translational Psychiatry, vol. 12, 291 . https://doi.org/10.1038/s41398-022-02060-3

Importance Multiplex schizophrenia families have higher recurrence risk of schizophrenia compared to the families of singleton cases in the population, but the source of increased familial recurrence risk is unknown. Determining the source of this ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cbb7de3772d26cebc24dda21347b85
https://pure.qub.ac.uk/en/publications/15adc2c2-bbca-4fc7-8ee9-998b1468310a

Investigating the source of increased bipolar and major depressive disorder polygenic risk in multiplex schizophrenia families

Autor: Brian C. Verrelli, Kenneth S. Kendler, Bradley Todd Webb, Silviu-Alin Bacanu, Tan-Hoang Nguyen, Brien P. Riley, Robert M. Kirkpatrick, Nathan A. Gillespie, Mohammad Ahangari

Psychotic and affective disorders often aggregate in the relatives of probands with schizophrenia (SCZ), and genetic studies show substantial genetic correlation among SCZ, bipolar disorder (BIP) and major depressive disorder (MDD). However, the natu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb4b391cd535f874e8a5a946494ac01a
https://doi.org/10.1101/2021.11.15.21266368