Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tan Hooi Min Grahn"'
Autor:
Lifang Luo, Wenjing Sun, Weijian Zhu, Shuhan Li, Wenqi Zhang, Xiaohui Xu, Daoquan Fang, Tan Hooi Min Grahn, Lei Jiang, Yihu Zheng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-13 (2021)
Abstract Cisplatin is one of the most effective chemotherapy drugs and is widely used in the treatment of cancer, including hepatocellular carcinoma (HCC) and cervical cancer, but its therapeutic benefit is limited by the development of resistance. O
Externí odkaz:
https://doaj.org/article/8cc679d715484536b36e4a30e27ca2c7
Autor:
Yang Liu, Maria Dahl, Shubhranshu Debnath, Michael Rothe, Emma M. Smith, Tan Hooi Min Grahn, Sarah Warsi, Jun Chen, Johan Flygare, Axel Schambach, Stefan Karlsson
Publikováno v:
Haematologica, Vol 107, Iss 2 (2021)
Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure disorder in which pure red blood cell aplasia is associated with physical malformations and a predisposition to cancer. Twentyfive percent of patients with DBA have mutations in a gene
Externí odkaz:
https://doaj.org/article/87a6fd29702a4a00ac393a879706be89
Autor:
Sarah Warsi, Ulrika Blank, Maria Dahl, Tan Hooi Min Grahn, Ludwig Schmiderer, Silja Andradottir, Stefan Karlsson
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
Life-long production of blood from hematopoietic stem cells (HSCs) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like self-renewal - a cardinal feature of HSCs. Bone morphogenetic proteins (BMP) have an establ
Externí odkaz:
https://doaj.org/article/37bbd038d752424c8e2625681ba76262
Autor:
Abhishek Gupta, Bijinu Balakrishnan, Shakun Karki, Mark Slayton, Sukanta Jash, Sayani Banerjee, Tan Hooi Min Grahn, Srikarthika Jambunathan, Sarah Disney, Hebaallaha Hussein, Dong Kong, Bradford B. Lowell, Purushothaman Natarajan, Umesh K. Reddy, Noyan Gokce, Vishva M. Sharma, Vishwajeet Puri
Publikováno v:
The Journal of biological chemistry. 298(9)
Cell death-inducing DNA fragmentation factor-like effector C (CIDEC) expression in adipose tissue positively correlates with insulin sensitivity in obese humans. Further, E186X, a single-nucleotide CIDEC variant is associated with lipodystrophy, hype
Autor:
Wenqi Zhang, Lei Jiang, Xiaohui Xu, Wenjing Sun, Lifang Luo, Yi-Hu Zheng, Daoquan Fang, Weijian Zhu, Tan Hooi Min Grahn, Shuhan Li
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 2, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 2, Pp 1-13 (2021)
Cisplatin is one of the most effective chemotherapy drugs and is widely used in the treatment of cancer, including hepatocellular carcinoma (HCC) and cervical cancer, but its therapeutic benefit is limited by the development of resistance. Our previo
Autor:
Yang, Liu, Maria, Dahl, Shubhranshu, Debnath, Michael, Rothe, Emma M, Smith, Tan Hooi Min, Grahn, Sarah, Warsi, Jun, Chen, Johan, Flygare, Axel, Schambach, Stefan, Karlsson
Publikováno v:
Haematologica. 107(2)
Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure disorder in which pure red blood cell aplasia is associated with physical malformations and a predisposition to cancer. Twentyfive percent of patients with DBA have mutations in a gene
Autor:
Sarah, Warsi, Ulrika, Blank, Maria, Dahl, Tan, Hooi Min Grahn, Ludwig, Schmiderer, Silja, Andradottir, Stefan, Karlsson
Publikováno v:
Haematologica
Life-long production of blood from hematopoietic stem cells (HSCs) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like self-renewal - a cardinal feature of HSCs. Bone morphogenetic proteins (BMP) have an establ
Autor:
Yi-Hu Zheng, Yan-Rong Zhao, Qi-Yu Zhang, Tan-Hooi-Min Grahn, Bi-Cheng Chen, Ye-Fan Zhu, Wei-Jian Hu, Hai-Li Bao
Publikováno v:
Liver International. 36:1836-1847
Background & Aims: BCAT1 initiates the catabolism of branched-chain amino acids. Here, we investigated the function of BCAT1 and its transcriptional regulatory mechanism in hepatocellular carcinoma (HCC). Methods: RNASeq was used to evaluate BCAT1 mR
Autor:
Roman A. Zubarev, Maroulio Pertesi, Sarah Warsi, Sandra Capellera-Garcia, Fatemeh Safi, Leal Oburoglu, Tan Hooi Min Grahn, Kavitha Siva, Natsumi Miharada, Yang Liu, Abhishek Niroula, Stefan Karlsson, Björn Nilsson, Ákos Végvári, Emma Rörby
Publikováno v:
Leukemia
The fate options of hematopoietic stem cells (HSCs) include self-renewal, differentiation, migration, and apoptosis. HSCs self-renewal divisions in stem cells are required for rapid regeneration during tissue damage and stress, but how precisely intr
Autor:
Nadège Gouignard, Dobromir Iliev, Edgar M. Pera, Helena Acosta, Mohsen Sagha, Marco Maccarana, Maria Climent, Tan Hooi Min Grahn, Julia Griesbach, Svende Herzmann
Publikováno v:
Development. 142:1146-1158
Germ layer formation and primary axis development rely on Fibroblast growth factors (FGFs). In Xenopus, the secreted serine protease HtrA1 induces mesoderm and posterior trunk/tail structures by facilitating the spread of FGF signals. Here, we show t