Site-selective chlorination of pyrrolic heterocycles by flavin dependent enzyme PrnC.

Autor: Peh G; Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Tay T; Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Tan LL; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Tiong E; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Bi J; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Goh YL; Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Ye S; Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Lin F; Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Tan CJX; Department of Biological Sciences, National University of Singapore, Singapore, Singapore., Tan YZ; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.; Disease Intervention Technology Laboratory (DITL), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Wong J; Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Zhao H; Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.; Department of Chemical and Biomolecular Engineering, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Wong FT; Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore. wongft@imcb.a-star.edu.sg.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore. wongft@imcb.a-star.edu.sg., Ang EL; Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore. ang_ee_lui@sifbi.a-star.edu.sg.; Synthetic Biology Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore. ang_ee_lui@sifbi.a-star.edu.sg., Lim YH; Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore. lim_yee_hwee@isce2.a-star.edu.sg.; Synthetic Biology Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore. lim_yee_hwee@isce2.a-star.edu.sg.

Publikováno v: Communications chemistry [Commun Chem] 2024 Jan 05; Vol. 7 (1), pp. 7. Date of Electronic Publication: 2024 Jan 05.