ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis.

Autor: Yuk Kien Chong, Sandanaraj, Edwin, Koh, Lynnette W. H., Thangaveloo, Moogaambikai, Tan, Melanie S. Y., Koh, Geraldene R. H., Toh, Tan Boon, Lim, Grace G. Y., Holbrook, Joanna D., Oi Lian Kon, Nadarajah, Mahendran, Ivan Ng, Wai Hoe Ng, Nguan Soon Tan, Kah Leong Lim, Carol Tang, Beng Ti Ang, Chong, Yuk Kien, Kon, Oi Lian, Ng, Ivan

Publikováno v: JNCI: Journal of the National Cancer Institute; Feb2016, Vol. 108 Issue 2, p1-12, 12p, 1 Chart, 6 Graphs

ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis.

Autor: Chong YK; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Sandanaraj E; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Koh LW; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Thangaveloo M; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Tan MS; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Koh GR; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Toh TB; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Lim GG; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Holbrook JD; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Kon OL; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Nadarajah M; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Ng I; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Ng WH; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Tan NS; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Lim KL; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA)., Tang C; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA). carol_tang@nni.com.sg beng_ti_ang@nni.com.sg yuk_kien_chong@nni.com.sg., Ang BT; Department of Research (YKC, ES, LWHK, MT, MSYT, GRHK, TBT, GGYL, KLL, CT), Department of Neuroradiology (MN), and Department of Neurosurgery (IN, WHN, BTA), National Neuroscience Institute, Singapore; Department of Physiology (YKC, KLL, BTA) and Department of Biochemistry (OLK), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences (ES, JDH, BTA) and Institute of Molecular and Cell Biology (NST), Agency for Science, Technology and Research (A*STAR), Singapore; School of Biological Sciences, Nanyang Technological University, Singapore (ES, LWHK, MSYT, NST); Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore (OLK, CT); Duke-National University of Singapore Graduate Medical School, Singapore (IN, WHN, KLL, CT, BTA). carol_tang@nni.com.sg beng_ti_ang@nni.com.sg yuk_kien_chong@nni.com.sg.

Publikováno v: Journal of the National Cancer Institute [J Natl Cancer Inst] 2015 Nov 07; Vol. 108 (2). Date of Electronic Publication: 2015 Nov 07 (Print Publication: 2016).