CXCL5 impedes CD8⁺ T cell immunity by upregulating PD-L1 expression in lung cancer via PXN/AKT signaling phosphorylation and neutrophil chemotaxis.

Autor: Sun, Dantong¹ (AUTHOR), Tan, Lipin² (AUTHOR), Chen, Yongbing¹ (AUTHOR), Yuan, Qiang³ (AUTHOR), Jiang, Kanqiu¹ (AUTHOR), Liu, Yangyang⁴ (AUTHOR), Xue, Yuhang⁵ (AUTHOR), Zhang, Jinzhi¹ (AUTHOR), Cao, Xianbao¹ (AUTHOR), Xu, Minzhao¹ (AUTHOR), Luo, Yang¹ (AUTHOR), Xu, Zhonghua¹ (AUTHOR), Xu, Zhonghen¹ (AUTHOR), Xu, Weihua¹ (AUTHOR), Shen, Mingjing¹ (AUTHOR) shenmingjing0707@126.com

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 7/22/2024, Vol. 43 Issue 1, p1-15. 15p.

CXCL5 impedes CD8 ⁺ T cell immunity by upregulating PD-L1 expression in lung cancer via PXN/AKT signaling phosphorylation and neutrophil chemotaxis.

Autor: Sun D; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Tan L; Department of nursing administration, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Chen Y; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Yuan Q; Department of interventional medicine, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Jiang K; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Liu Y; Department of Vascular Surgery, Hospital of Zhangjiagang, Suzhou, 215600, China., Xue Y; Department of Thoracic Surgery, Hospital of Yancheng, Yancheng, 224000, China., Zhang J; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Cao X; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Xu M; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Luo Y; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Xu Z; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Xu Z; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Xu W; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China., Shen M; Department of Thoracic and Cardiac Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China. shenmingjing0707@126.com.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jul 22; Vol. 43 (1), pp. 202. Date of Electronic Publication: 2024 Jul 22.