Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tamzin, Tanner"'
Autor:
Jerald, Sadoff, Glenda, Gray, An, Vandebosch, Vicky, Cárdenas, Georgi, Shukarev, Beatriz, Grinsztejn, Paul A, Goepfert, Carla, Truyers, Hein, Fennema, Bart, Spiessens, Kim, Offergeld, Gert, Scheper, Kimberly L, Taylor, Merlin L, Robb, John, Treanor, Dan H, Barouch, Jeffrey, Stoddard, Martin F, Ryser, Mary A, Marovich, Kathleen M, Neuzil, Lawrence, Corey, Nancy, Cauwenberghs, Tamzin, Tanner, Karin, Hardt, Javier, Ruiz-Guiñazú, Mathieu, Le Gars, Hanneke, Schuitemaker, Johan, Van Hoof, Frank, Struyf, Macaya, Douoguih, Marcus, Zervos
Publikováno v:
New England Journal of Medicine. 384:2187-2201
The Ad26.COV2.S vaccine is a recombinant, replication-incompetent human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a prefusion-stabilized conformation.In an internation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee15932e9c6292bf57ca0d0bf206bc00
https://doi.org/10.1056/nejmoa2101544
https://doi.org/10.1056/nejmoa2101544
Autor:
Christine Helsen, Frank Claessens, Stefanie Kerkhofs, Vanessa Dubois, Nora Van Tilborgh, Annemie Haelens, Lien Spans, Adriaan B. Houtsmuller, Tamzin Tanner, Sarah Denayer, Bart Geverts
Publikováno v:
Cellular and Molecular Life Sciences. 67:1919-1927
The androgen receptor protein has specific domains involved in DNA binding, ligand binding, and transactivation, whose activities need to be integrated during transcription activation. The hinge region, more particular a (629)RKLKK(633) motif, seems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a7cf1e3716731ac2ce006de97e112f
https://doi.org/10.1007/s00018-010-0302-1
https://doi.org/10.1007/s00018-010-0302-1
The androgen receptor DNA-binding domain determines androgen selectivity of transcriptional response
Publikováno v:
Biochemical Society Transactions. 34:1089-1094
The AR (androgen receptor) is a hormone-dependent transcription factor that translates circulating androgen hormone levels into a physiological cellular response by directly regulating the expression of its target genes. It is the key molecule in e.g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be057dd52f77bca3dfda3db04783f64
https://doi.org/10.1042/bst0341089
https://doi.org/10.1042/bst0341089
Autor:
Aria Baniahmad, Rudolf Matusch, Maria Papaioannou, Undine Schubert, Sonja Schleich, Tamzin Tanner, Frank Claessens, Daniella Roell
Extracts from Pygeum africanum are used in the treatment of prostatitis, benign prostatic hyperplasia (BPH) and prostate cancer (PCa). The ligand-activated human androgen receptor (AR) is known to control the growth of the prostate gland. Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0729c10ab232fd2404d6ea6b65beaafa
https://lirias.kuleuven.be/handle/123456789/270811
https://lirias.kuleuven.be/handle/123456789/270811
Publikováno v:
Androgen Action in Prostate Cancer ISBN: 9780387691770
The androgen receptor, like the other nuclear receptors, consists of three canonical domains: the aminoterminal domain (NTD), the DNA-binding domain (DBD) and the ligand-binding domain (LBD). The flexible hinge between the DBD and LBD can also be con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a71c7c7d5033bdd15c051fadd74cabb
https://doi.org/10.1007/978-0-387-69179-4_17
https://doi.org/10.1007/978-0-387-69179-4_17
Autor:
Aria Baniahmad, Rudolf Matusch, Undine Schubert, Stephanie Degen, Maria Papaioannou, Frank Claessens, Daniela Roell, Tamzin Tanner, Sonja Schleich, Ina Prade
Publikováno v:
Journal of cellular and molecular medicine. 13(8B)
Extracts from Pygeum africanum are used in the treatment of prostatitis, benign prostatic hyperplasia and prostate cancer (Pca), major health problems of men in Western countries. The ligand-activated human androgen receptor (AR) supports the growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44190967e013fde81752289fba0768b
https://pubmed.ncbi.nlm.nih.gov/18627423
https://pubmed.ncbi.nlm.nih.gov/18627423
Publikováno v:
Cancer research. 67(9)
The androgen receptor (AR) encoding gene can undergo mutations during the development and treatment of prostate cancer. Even in hormone-independent stages, mutations in the receptor paradoxically seem to result in an increased AR function. Two such p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3994d25e725b6aaf86dbb345313d4ce
https://pubmed.ncbi.nlm.nih.gov/17483368
https://pubmed.ncbi.nlm.nih.gov/17483368
Publikováno v:
Annals of the New York Academy of Sciences. 1030
To investigate the function of the hinge region in transcriptional activation by the androgen receptor, we compared the actions of the wild-type receptor with a mutant receptor, deleted of amino acids 628-646 of the hinge. The role of the proteasome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc04e90ce961b5d42ec08adc0e4e08d9
https://pubmed.ncbi.nlm.nih.gov/15659841
https://pubmed.ncbi.nlm.nih.gov/15659841
Autor:
Anna Haelens, Frank Claessens, Nora Van Tilborgh, Kris Schauwaers, U Moehren, Guy Verrijdt, Leen Callewaert, Tamzin Tanner, A d'Alesio, Sarah Denayer
Publikováno v:
Andrologia. 37:209-210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::340eee1adab8dfba5842f5b30a665c60
https://doi.org/10.1111/j.1439-0272.2005.00698.x
https://doi.org/10.1111/j.1439-0272.2005.00698.x