Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Tamsin M. Lindstrom"'
Autor:
William H. Robinson, Joel D. Taurog, Xiaoyan Zhao, Tamsin M. Lindstrom, Chang Keun Lee, John D. Reveille, Dong Hyun Sohn, Jeremy Sokolove, Bin Yoo, Yong-Gil Kim
Publikováno v:
Arthritis & Rheumatology. 66:2793-2803
Objective Although ankylosing spondylitis (AS) is driven by immune-mediated processes, little is known about the presence and role of autoantibodies in this disease. This study was undertaken to investigate whether autoantibodies occur in and are inv
Autor:
Daniel R. Lu, William H. Robinson, Sarah Kongpachith, Tamsin M. Lindstrom, Jeremy Sokolove, Yann-Chong Tan, Emily A. Stein, Xiaoyong Cai
Publikováno v:
Clinical Immunology. 152:77-89
Infection by Staphylococcus aureus is on the rise, and there is a need for a better understanding of host immune responses that combat S. aureus. Here we use DNA barcoding to enable deep sequencing of the paired heavy- and light-chain immunoglobulin
Autor:
Tamsin M. Lindstrom, Yann-Chong Tan, Xiaoyong Cai, Lisa K. Blum, Jeremy Sokolove, William H. Robinson, Chia-Hsin Ju, Sarah Kongpachith
Publikováno v:
Clinical Immunology. 151:55-65
We developed a DNA barcoding method to enable high-throughput sequencing of the cognate heavy- and light-chain pairs of the antibodies expressed by individual B cells. We used this approach to elucidate the plasmablast antibody response to influenza
Autor:
Catriona A. Wagner, Constance R. Chu, Jeremy Sokolove, William H. Robinson, Christin M. Lepus, Lawrence L.K. Leung, Tamsin M. Lindstrom, Jason Jungsik Song, Qian Wang
Publikováno v:
Arthritis & Rheumatology. 66:101-106
Objective We previously demonstrated that carboxypeptidase B (CPB) protects against joint erosion in rheumatoid arthritis by inactivating complement component C5a. We also found that levels of CPB are abnormally high in the synovial fluid of individu
Autor:
Catriona A. Wagner, Lauren J. Lahey, Saedis Saevarsdottir, Roger P. Walker, Steven R. Binder, Piyanka E Chandra, Jeremy Sokolove, William H. Robinson, Michelle Delanoy, Lars Klareskog, Lars Alfredsson, Camilla Bengtsson, Tamsin M. Lindstrom, Reuven Bromberg
Publikováno v:
Annals of the Rheumatic Diseases
Introduction A hallmark of rheumatoid arthritis (RA) is the development of autoantibodies targeting proteins that contain citrulline. Anticitrullinated protein antibodies (ACPAs) are currently detected by the commercial cyclic citrullinated peptide (
Autor:
Qian Wang, Christin M. Lepus, Harini Raghu, Rong Mao, Jeremy Sokolove, Tamsin M. Lindstrom, William H. Robinson
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but accumulating evidence indicates that inflammation has a critical role in its pathogenesis. Furthermore, we now appreciate that OA pathogenesis involves not only brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8845bb3096cb48e6fefe1c49ad51ffc3
https://europepmc.org/articles/PMC5500215/
https://europepmc.org/articles/PMC5500215/
Autor:
C. Garrison Fathman, Scott D. Boyd, Matthew Hale, Tamsin M. Lindstrom, Paul J. Utz, William H. Robinson, Holden T. Maecker, Shai S. Shen-Orr
Publikováno v:
Nature Reviews Rheumatology. 8:317-328
Rheumatologists see patients with a range of autoimmune diseases. Phenotyping these diseases for diagnosis, prognosis and selection of therapies is an ever increasing problem. Advances in multiplexed assay technology at the gene, protein, and cellula
Autor:
Abdolhossein Edalati, Emily A. Stein, Jacob D. Petralia, Elliot H. Akama-Garren, Pedro J. Ruiz, Christina D. Swanson, Tamsin M. Lindstrom, William H. Robinson
Publikováno v:
The Journal of Immunology. 188:3513-3521
Rheumatoid arthritis (RA) is an autoimmune synovitis characterized by the formation of pannus and the destruction of cartilage and bone in the synovial joints. Although immune cells, which infiltrate the pannus and promote inflammation, play a promin
Autor:
Leonardo Punzi, David M. Lee, Tamsin M. Lindstrom, Heidi H. Wong, Carla R. Scanzello, Gurkan Bebek, Christin M. Lepus, Mary K. Crow, V. Michael Holers, Tony Wyss-Coray, James F. Crish, Jason J. Song, Inyong Hwang, Susan Y. Ritter, Angelo Encarnacion, Steven R. Goldring, Joshua M. Thurman, Stuart B. Goodman, William H. Robinson, Andrew L. Rozelle, Reuben Gobezie, Mehrdad Shamloo, Nirmal K. Banda, D Meegan Larsen, Qian Wang
Publikováno v:
Nature Medicine. 17:1674-1679
Osteoarthritis, characterized by the breakdown of articular cartilage in synovial joints, has long been viewed as the result of 'wear and tear'. Although low-grade inflammation is detected in osteoarthritis, its role is unclear. Here we identify a ce
Publikováno v:
Journal of the American Geriatrics Society. 58:1565-1575
Aging is accompanied by a progressive decline in the integrity of the immune system, a process known as immunosenescence. Pathological features typical of immune dysfunction in older adults, encompassing dysregulation of innate and adaptive immune re