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pro vyhledávání: '"Tamrat Meshka Mamo"'
Autor:
Shuang Geng, Fabian Paul, Izabela Kowalczyk, Sandra Raimundo, Anje Sporbert, Tamrat Meshka Mamo, Annette Hammes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The specification of the forebrain relies on the precise regulation of WNT/ß-catenin signalling to support neuronal progenitor cell expansion, patterning, and morphogenesis. Imbalances in WNT signalling activity in the early neuroepithelium lead to
Externí odkaz:
https://doaj.org/article/25ae0a0861c940ef8683fe4fea9e0e64
Autor:
Tamrat Meshka Mamo, Annette Hammes
Publikováno v:
Neuroforum. 28:233-243
Patients carrying pathogenic gene variants encoding factors linked to the sonic hedgehog (SHH) pathway suffer from severe congenital brain malformations including holoprosencephaly (HPE). A poorly understood feature of these common anomalies is the h