Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing.

Autor: Appelbaum J; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.; Division of Hematology/Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.; Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Seattle Children's Hospital, Seattle, Washington, USA., Price AE; 2seventy bio, Cambridge, Massachusetts, USA., Oda K; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Zhang J; 2seventy bio, Cambridge, Massachusetts, USA., Leung WH; 2seventy bio, Cambridge, Massachusetts, USA., Tampella G; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Xia D; 2seventy bio, Cambridge, Massachusetts, USA., So PP; 2seventy bio, Cambridge, Massachusetts, USA., Hilton SK; 2seventy bio, Cambridge, Massachusetts, USA., Evandy C; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Sarkar S; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Martin U; 2seventy bio, Cambridge, Massachusetts, USA., Krostag AR; 2seventy bio, Cambridge, Massachusetts, USA., Leonardi M; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Zak DE; 2seventy bio, Cambridge, Massachusetts, USA., Logan R; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Lewis P; 2seventy bio, Cambridge, Massachusetts, USA., Franke-Welch S; 2seventy bio, Cambridge, Massachusetts, USA., Ngwenyama N; 2seventy bio, Cambridge, Massachusetts, USA., Fitzgerald M; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Tulberg N; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Rawlings-Rhea S; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Gardner RA; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Jones K; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Sanabria A; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Crago W; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Timmer J; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Hollands A; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Eckelman B; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Bilic S; Vandro Consulting, Waukee, Iowa, USA., Woodworth J; Vandro Consulting, Waukee, Iowa, USA., Lamble A; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.; Seattle Children's Hospital, Seattle, Washington, USA., Gregory PD; 2seventy bio, Cambridge, Massachusetts, USA., Jarjour J; 2seventy bio, Cambridge, Massachusetts, USA., Pogson M; 2seventy bio, Cambridge, Massachusetts, USA., Gustafson JA; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Astrakhan A; 2seventy bio, Cambridge, Massachusetts, USA., Jensen MC; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Mar 19; Vol. 134 (9). Date of Electronic Publication: 2024 Mar 19.

Mutations in LRBA are Associated with a Syndrome of Immune Deficiency and Autoimmunity

Autor: Lopez-Herrera, G, Tampella, G, Baronio, M, Vitali, M, Lougaris, V, Plebani, A, Pan-Hammarstroem, Q, Hammarstroem, L, Du, L, Hultenby, K, Trujillo-Vargas, C, Phadwal, K, Simon, A, Moutschen, M, Etzioni, A, Srugo, A, Melamed, D, Liu, C, Philippet, P, Dideberg, V, Aghamohammadi, A, Rezai, N, Enright, V, Stauss, H, Herholz, P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::00ababe9ce2c3818ff9f54b89ffa059a
https://ora.ox.ac.uk/objects/uuid:9777ba20-2b83-422b-bf28-7730f22f5189

DELETERIOUS LRBA MUTATIONS IN A NOVEL SYNDROME OF IMMUNE DEFICIENCY AND AUTOIMMUNITY

Autor: GABRIELA LOPEZ HERRERA, Tampella, G., Pan-Hammarstrom, Q., Herholz, P., Trujillo-Vargas, C. M., Phadwal, K., Simon, A. K., Moutschen, M., Etzioni, A., Mory, A., Srugo, I., Melamed, D., Hultenby, K., Liu, C., Baronio, M., Vitali, M., Philippet, P., Dideberg, V., Aghamohammadi, A., Rezai, N., Enright, V., Du, L., Salzer, U., Eibel, H., Pfeifer, D., Veelken, H., Stauss, H., Lougaris, V., Plebani, A., Gertz, E. M., Schaeffer, A. A., Hammarstrom, L., Grimbacher, B.

Publikováno v: Journal of Clinical Immunology, 32, 251-251
Web of Science

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7abc08660bc2fe7fa6c98ebe6cb13300
http://hdl.handle.net/1887/97635

Evaluation of CARMA1/CARD11 and Bob1 as candidate genes in common variable immunodeficiency

Autor: Tampella, G., Baronio, M., Vitali, M., Soresina, A., Raffaele Badolato, Giliani, S., Plebani, A., Lougaris, V.

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::34e9a837a94abcaa7f99f61ec7aee02f
http://hdl.handle.net/11379/81860

Clinical, Immunological, and Genetic Features in Patients with NFKB1 and NFKB2 Mutations: a Systematic Review.

Autor: Fathi N; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Nirouei M; Alborz University of Medical Sciences, Karaj, Iran., Salimian Rizi Z; Department of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Fekrvand S; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Abolhassani H; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Salami F; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Ketabforoush AHME; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran., Azizi G; Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.; Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA., Saghazadeh A; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Systematic Review and Meta-Analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Esmaeili M; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Almasi-Hashiani A; Department of Epidemiology, School of Health, Arak University of Medical Sciences, Arak, Iran., Rezaei N; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. rezaei_nima@tums.ac.ir.; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. rezaei_nima@tums.ac.ir.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2024 Jul 11; Vol. 44 (7), pp. 160. Date of Electronic Publication: 2024 Jul 11.