Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Tamotsu Yoshioka"'
Publikováno v:
Journal of Health Science. 54:224-228
An analytical method for the quantitative determination of monobutyltin (MBT), dibutyltin (DBT), tributyltin (TBT) and triphenyltin (TPhT) compounds in human breast milk is described. After the addition of surrogates (deuterium derivatives), milk sam
Autor:
Akira Harashima, Tamotsu Yoshioka, Mayuko Yamamoto, Ayumi Okochi, Kunzo Orita, Motoyuki Suzuki, Yoshinobu Matsuo, Ryuichi Motoda
Publikováno v:
Experimental Hematology. 30:1132-1138
Objective Several investigators have reported that transforming growth factor (TGF)- β 1 and granulocyte-macrophage colony-stimulating factor (GM-CSF) synergistically support cell proliferation. However, the mechanisms involved have not been elucida
Publikováno v:
Journal of Biochemistry. 129:35-41
We previously reported that in addition to mitochondrial cytochrome c dependent activation, lysosomal cysteine proteases were also involved in the activation of caspase-3. In this study, we have separately obtained the lysosomal and mitochondrial cas
Publikováno v:
Free Radical Research. 32:507-514
Nitric oxide (NO) from (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1- ium-1,2-diolate (NOC-18) induces apoptosis in human leukemia HL-60 cells. This effect was prevented by the pan-caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluorometh
Autor:
Kozo Utsumi, Rumi Ishisaka, Tatsuji Yasuda, Tamotsu Yoshioka, Munehisa Yabuki, Alan A. Horton, Shinji Kariya
Publikováno v:
Free Radical Biology and Medicine. 26:325-332
Nitric oxide (NO) released from (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1- ium-1,2-diolate (DETA/NO or NOC-18) induces apoptosis in human leukemia HL-60 cells. In this study, we isolated a HL-60 variant cell line, HL-NR6, that is resis
Autor:
Tatsuji Yasuda, Tamotsu Yoshioka, Tomoko Kanno, Rumi Ishisaka, Hiroshi Kanematsu, Alan A. Horton, Hiroko Nakahara, Jitsuo Akiyama
Publikováno v:
Neonatology. 76:331-339
Human oral polymorphonuclear neutrophils (OPMN) generate reactive oxygen species even in the absence of stimulants. Because OPMN from newborn babies are exposed to colostrum and mature milk, the biological properties of these cells including the gene
Autor:
Tatsuji Yasuda, Tamotsu Yoshioka, Yoko Inai, Kozo Utsumi, Hamazaki K, Masayasu Inoue, Munehisa Yabuki
Publikováno v:
Free Radical Research. 26:245-255
Although active oxygen species and related metabolites, such as nitric oxide (NO), have been postulated to play important roles in the apoptosis of various cells, a precise mechanism leading to cell death remains to be elucidated. Recently we found t
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 22:507-516
Objectives: Alfa-tocopherol (VE) inhibits protein phosphorylation and affects protein kinase C (PKC)-dependent superoxide (O2-) generation of phagocytic cells. Because umbilical-cord blood contains low concentrations of VE, we studied the effects of
Publikováno v:
Archives of Biochemistry and Biophysics. 323:27-32
To elucidate the role of nitric oxide (NO) in the regulation of mitochondrial function, the effect of NO on energy transfer reactions was examined under different oxygen tensions. Mitochondrial respiration was remarkably inhibited by NO resulting in
Autor:
Tomoko Kanno, Tamotsu Yoshioka, Minoru Okuma, Yuhzo Fujita, Kozo Utsumi, Yoshiki Takehara, Takahiko Utsumi, Alan A. Horton
Publikováno v:
Biochemical Pharmacology. 50:655-662
The photosensitizing effect of hypericin (HY), an antiretroviral agent, on the functions of isolated rat liver mitochondria has been investigated. The respiratory control ratio (RCR), ADP/O and membrane potential of mitochondria were decreased by HY