Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tamotsu, Ichiba"'
Autor:
Tamotsu, Ichiba
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 42
Notification of cancer is essential for medical treatment based on patient preference. I studied 45 terminally-ill cancer patients referred to my clinic from January 2012 to December 2013. The data of each patient was retrospectively collected from t
Autor:
Yasuhiro Arakawa, Kazumi Kawase, Naomi Ando, Chihiro Kanehira, Tamotsu Ichiba, Yasunobu Kuraishi, Tadashi Kobayashi, Toshikazu Sakuyama, Kazuhiko Natori, Masao Kobayashi, Masafumi Suzuki, Eijiroh Nagasaki, Hiroko Nogi, Keisuke Aiba, Yasuo Toriumi, Ken Uchida, Hiroshi Takeyama
Publikováno v:
Breast Cancer. 19:218-237
Metastatic breast cancer (MBC) is generally incurable. However, 10-20-year relapse-free survival of MBC is approximately 2%, implying that at least a small subset of MBC patients achieve prolonged survival. We therefore analyzed long-term outcome in
Autor:
Tamotsu Ichiba, Keisuke Aiba, Kazunori Ochiai, Yasumasa Tanzfuii, Toshikazu Sakuyama, Daisuke Inoue, Tadashi Kobayashi
Publikováno v:
Drug Delivery System. 20:513-520
疼痛管理の最大の目的は, 傷害された組織による痛みのストレスを最小限にすることである. 本稿では, 疼痛管理によく用いられている, 神経ブロック, 薬物療法, 種々の持続注入ポンプに
Autor:
Tamotsu Ichiba, Samir M. Hanash, Yoshinobu Maeda, Yuichiro Takada, James L.M. Ferrara, David E. Misek, Rork Kuick, Chen Liu, Debra L. Williams, Takanori Teshima, Pavan Reddy
Publikováno v:
Blood. 102:763-771
The liver, skin, and gastrointestinal tract are major target organs of acute graft-versus-host disease (GVHD), the major complication of allogeneic bone marrow transplantation (BMT). In order to gain a better understanding of acute GVHD in the liver,
Publikováno v:
FEBS Letters. 457:85-89
Three groups of Rap1-specific guanine nucleotide exchange factors including C3G, CalDAG-GEFI, and Epac/cAMP-GEFI/II have been identified to date. In the present study, we report a new Rap1 guanine nucleotide exchange factor which we have named GFR (g
Autor:
Takeshi Kurata, Mie Nakaya, Shinya Tanaka, Yasunobu Kuraishi, Yuko Hashimoto, Naoki Mochizuki, Tamotsu Ichiba, Michiyuki Matsuda
Publikováno v:
Journal of Biological Chemistry. 274:14376-14381
C3G is a guanine nucleotide exchange factor for Rap1 and is activated by the expression of Crk adaptor proteins. We found that expression of CrkI in COS cells induced significant tyrosine phosphorylation of C3G. To understand the mechanism by which C
Autor:
Tamotsu Ichiba, Michiyuki Matsuda, Osamu Sakai, John Groffen, Takeshi Kurata, Seisuke Hattori, Satoshi Nagata, Yasunobu Kuraishi
Publikováno v:
Journal of Biological Chemistry. 272:22215-22220
Crk is an adaptor protein that consists almost entirely of SH2 and SH3 domains. We have previously demonstrated, by using in vivo and in vitro systems, that C3G, which was identified as a Crk SH3 domain-binding guanine nucleotide exchange factor, spe
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1262:83-86
An ornithine decarboxylase antizyme cDNA was obtained from Xenopus laevis liver and its sequence was determined. The cDNA consists of two major open reading frames as found in mammalian antizymes, which require +1 ribosomal frameshifting for its tran
Autor:
Daisuke, Inoue, Toshikazu, Sakuyama, Tamotsu, Ichiba, Tadashi, Uwagawa, Yasuhiro, Arakawa, Eijiroh, Nagasaki, Akitaka, Yoshizawa, Takaaki, Matsumoto, Keisuke, Aiba
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 38
The epidural block therapy is offered to reduce one of the side effects of systemic administration of opioids such as drowsiness. Hence, it is necessary to set a subcutaneous reservoir to prevent a catheter-related infection for a long period of time
Autor:
Tamotsu, Ichiba, Tadashi, Kobayashi, Daisuke, Inoue, Yasuhiro, Arakawa, Toshikazu, Sakuyama, Keisuke, Aiba
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 36
Although a cancer patient to die at home has been arranged much easier due to a change in homecare service environment, the patient to die at home is not always possible. In the present study, we reviewed an outpatient who received chemotherapy and e