Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Tammy Y. Fields"'
1
Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog
Autor: K.L. Powell, Erika L. Abel, Elizabeth McIvor, Stephen B. Boulware, Michael C. MacLeod, Karen M. Vasquez, John DiGiovanni, Tammy Y. Fields
Publikováno v: Toxicology and Applied Pharmacology. 266:439-442
Mustard gas, used in chemical warfare since 1917, is a mutagenic and carcinogenic agent that produces severe dermal lesions for which there are no effective therapeutics; it is currently seen as a potential terrorist threat to civilian populations. S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4dcf4f9d7db86b78b6bafad14d7218
https://doi.org/10.1016/j.taap.2012.11.020
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2
2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog
Autor: Tammy Y. Fields, Elizabeth McIvor, Stephen B. Boulware, Michael C. MacLeod, Erika L. Abel, Karen M. Vasquez, K. Leslie Powell
Publikováno v: Toxicology and Applied Pharmacology. 263:203-209
Sulfur mustard [bis(2-chloroethyl)sulfide, SM] is a well-known DNA-damaging agent that has been used in chemical warfare since World War I, and is a weapon that could potentially be used in a terrorist attack on a civilian population. Dermal exposure
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68072f15fbf0ac9ac04b4b257894058e
https://doi.org/10.1016/j.taap.2012.06.010
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3
Gi/Go Couple Met–Enkephalin to Inhibition of Cholinergic and β-Adrenergic Stimulation of Lacrimal Secretion
Autor: Michele A. Meneray, D J Bennett, Tammy Y. Fields
Publikováno v: Cornea. 19:92-98
PURPOSE To determine whether G-protein-mediated inhibition of secretion by met-enkephalin involves cyclic adenosine monophosphate (cAMP)-dependent events and to identify the G proteins that couple met-enkephalin to inhibition of lacrimal secretion. M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bce40717eb8970103a261a92158edeb
https://doi.org/10.1097/00003226-200001000-00018
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5
G Protein Coupling of Receptor Activation to Lacrimal Secretion
Autor: Tammy Y. Fields, Michele A. Meneray
Publikováno v: Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2 ISBN: 9781461374459
In lacrimal gland, protein secretion involves transduction of extracellular signals generated by neurotransmitters and neuromodulators of the parasympathetic and sympathetic nerve fibers that innervate the gland. In this gland, as in other exocrine t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b409f438f2d58d9cbadf3aa17f97ed0d
https://doi.org/10.1007/978-1-4615-5359-5_18
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6
Abstract 1339: Upregulation of the glutathione detoxification pathway protects against cytotoxicity induced by the alkylating agent, 2-chloroethyl ethyl sulfide (CEES)
Autor: Tammy Y. Fields, Michael C. MacLeod, John DiGiovanni, Michael Andreeff, Leslie Powell, Erika L. Abel, Jennifer D. Bubel, Elizabeth McIvor, Melissa S. Simper
Publikováno v: Cancer Research. 71:1339-1339
Sulfur mustard (SM) is a vesicating agent that was first used in chemical warfare over 100 years ago. SM alkylates DNA and is mutagenic in various model systems. Epidemiological studies indicate that chronic exposure increases the risk of cancer in e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bb33117baee098037db5e718901c5ee
https://doi.org/10.1158/1538-7445.am2011-1339
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