Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Tammy Szu-Yu Ho"'
Autor:
Andrew R. Snavely, Keungjung Heo, Veselina Petrova, Tammy Szu-Yu Ho, Xuan Huang, Crystal Hermawan, Ruth Kagan, Tao Deng, Ilyas Singeç, Long Chen, Lee B. Barret, Clifford J. Woolf
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 12 (2022)
Externí odkaz:
https://doaj.org/article/a512aa7304b94a7791b928b38bd35c2b
Autor:
Cheng-Hsin Liu, Ryan Seo, Tammy Szu-Yu Ho, Michael Stankewich, Peter J Mohler, Thomas J Hund, Jeffrey L Noebels, Matthew N Rasband
Publikováno v:
eLife, Vol 9 (2020)
Previously, we showed that a hierarchy of spectrin cytoskeletal proteins maintains nodal Na+ channels (Liu et al., 2020). Here, using mice lacking β1, β4, or β1/β4 spectrins, we show this hierarchy does not function at axon initial segments (AIS)
Externí odkaz:
https://doaj.org/article/b0a80c607d4b4ee5b9e6ed64b25767e2
Autor:
Pabitra K. Sahoo, Seung Joon Lee, Poonam B. Jaiswal, Stefanie Alber, Amar N. Kar, Sharmina Miller-Randolph, Elizabeth E. Taylor, Terika Smith, Bhagat Singh, Tammy Szu-Yu Ho, Anatoly Urisman, Shreya Chand, Edsel A. Pena, Alma L. Burlingame, Clifford J. Woolf, Mike Fainzilber, Arthur W. English, Jeffery L. Twiss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
G3BP1 is RasGAP SH3 domain binding protein 1 that interacts with 48S pre-initiation complex when translation is stalled. Here, Twiss and colleagues show that neuronal G3BP1 can negatively regulate axonal mRNA translation, and inhibit axonal regenerat
Externí odkaz:
https://doaj.org/article/54f17aef7ce54eff8c30573b11316ce9
Autor:
Joseph G Duman, Shalaka Mulherkar, Yen-Kuei Tu, Kelly C Erikson, Christopher P Tzeng, Vasilis C Mavratsas, Tammy Szu-Yu Ho, Kimberley F Tolias
Publikováno v:
eLife, Vol 8 (2019)
Dendritic arbor architecture profoundly impacts neuronal connectivity and function, and aberrant dendritic morphology characterizes neuropsychiatric disorders. Here, we identify the adhesion-GPCR BAI1 as an important regulator of dendritic arborizati
Externí odkaz:
https://doaj.org/article/b58edcaccc764d3c8e90a12ed9ee0a1a
Publikováno v:
eLife, Vol 5 (2016)
Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by mutations in Frataxin (FXN). Loss of FXN causes impaired mitochondrial function and iron homeostasis. An elevated production of reactive oxygen species (ROS) w
Externí odkaz:
https://doaj.org/article/b795688a74a048bcb40712b38d7070cf
Autor:
Kuchuan Chen, Guang Lin, Nele A Haelterman, Tammy Szu-Yu Ho, Tongchao Li, Zhihong Li, Lita Duraine, Brett H Graham, Manish Jaiswal, Shinya Yamamoto, Matthew N Rasband, Hugo J Bellen
Publikováno v:
eLife, Vol 5 (2016)
Mutations in Frataxin (FXN) cause Friedreich’s ataxia (FRDA), a recessive neurodegenerative disorder. Previous studies have proposed that loss of FXN causes mitochondrial dysfunction, which triggers elevated reactive oxygen species (ROS) and leads
Externí odkaz:
https://doaj.org/article/d43500dee4974bd596fee8b639e61034
Autor:
Tammy Szu-Yu Ho, J. Tabitha Hees, Zhuqiu Xu, Riki Kawaguchi, Natalia P. Biscola, Daniel G Taub, Kuchuan Chen, Xirui Chen, Lee B. Barrett, Long Cheng, Christopher V. Gabel, Leif A. Havton, Daniel H. Geschwind, Clifford J. Woolf
SummaryCNS neurons do not regenerate after injury, leading to permanent functional deficits. Although sensory and motor neuron axons do regrow after peripheral nerve injury, functional outcome is limited due to the incomplete and slow regrowth. The l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e159f8008a764a2e520e980818808483
https://doi.org/10.1101/2021.11.02.466937
https://doi.org/10.1101/2021.11.02.466937
Autor:
Michael C. Stankewich, Matthew N. Rasband, Peter J. Mohler, Cheng-Hsin Liu, Jeffrey L. Noebels, Ryan Seo, Thomas J. Hund, Tammy Szu-Yu Ho
Publikováno v:
eLife, Vol 9 (2020)
Previously, we showed that a hierarchy of spectrin cytoskeletal proteins maintains nodal Na+ channels (Liu et al., 2020). Here, using mice lacking β1, β4, or β1/β4 spectrins, we show this hierarchy does not function at axon initial segments (AIS)
Autor:
Jeffrey L. Noebels, Thomas J. Hund, Cheng-Hsin Liu, Tammy Szu-Yu Ho, Peter J. Mohler, Ryan Seo, Michael C. Stankewich, Matthew N. Rasband
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e31687f5cb5cafd722e5f4e8ba118f
https://doi.org/10.7554/elife.56629.sa2
https://doi.org/10.7554/elife.56629.sa2
Autor:
Juan A. Oses-Prieto, Tammy Szu-Yu Ho, Alma L. Burlingame, Hamdan Hamdan, Tomohiro Torii, Chih-chuan Wang, Cheng-Hsin Liu, Yuki Ogawa, Matthew N. Rasband
Publikováno v:
The Journal of cell biology, vol 219, iss 2
The Journal of Cell Biology
The Journal of Cell Biology
Abouelezz and Hotulainen preview work from Torii et al. that describes a role for NuMA1 in the early stages of axon initial segment assembly.
Axon initial segment (AIS) functionality relies on a specific organization of the AIS with high enrichm
Axon initial segment (AIS) functionality relies on a specific organization of the AIS with high enrichm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea3d98d7c4d8d43df25bc454841fdf2
https://escholarship.org/uc/item/5nx7k4db
https://escholarship.org/uc/item/5nx7k4db