Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tammy Stefan"'
Autor:
Masumi Ueda, Tammy Stefan, Lindsay Stetson, James J. Ignatz-Hoover, Benjamin Tomlinson, Richard J. Creger, Brenda Cooper, Hillard M. Lazarus, Marcos de Lima, David N. Wald, Paolo F. Caimi
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Glycogen synthase kinase-3 (GSK3) inhibitors induce differentiation and growth inhibition of acute myeloid leukemia (AML) cells. Our pre-clinical studies showed GSK3 inhibition leads to sensitization of AML cells to tretinoin-mediated differentiation
Externí odkaz:
https://doaj.org/article/7a3b5042e3c04c95a7f9e16640dfa4ff
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30870 (2012)
An imprecise quantitative sense for the oscillating levels of proteins and their modifications, interactions, and translocations as a function of the cell cycle is fundamentally important for a cartoon/narrative understanding for how the cell cycle w
Externí odkaz:
https://doaj.org/article/cec9bc4623664e4ba85bda871bc3588d
Autor:
David N. Wald, Yogen Saunthararajah, Gary Parizher, Stephen Moreton, James Ignatz-Hoover, Tammy Stefan, Kalpana Gupta
Pathways exhibiting significant changes in activation after 1,25D and GSK3 inhibitor treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e5f0564a402a46994e3c2b623ae871
https://doi.org/10.1158/0008-5472.22410356.v1
https://doi.org/10.1158/0008-5472.22410356.v1
Autor:
David N. Wald, Yogen Saunthararajah, Gary Parizher, Stephen Moreton, James Ignatz-Hoover, Tammy Stefan, Kalpana Gupta
Genes exhibiting significant changes in the gene expression after 1,25D and GSK3 inhibitor treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a658170dd5704b6a13d96070d5e7af
https://doi.org/10.1158/0008-5472.22410359
https://doi.org/10.1158/0008-5472.22410359
Autor:
David N. Wald, Yogen Saunthararajah, Gary Parizher, Stephen Moreton, James Ignatz-Hoover, Tammy Stefan, Kalpana Gupta
Western blot control for GSK3β knockdown, rrimer sequences for real-time PCR and FAB subtype and known genetic information on AML cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee8cea98e1dbdec90b8dc690de934a1
https://doi.org/10.1158/0008-5472.22410347
https://doi.org/10.1158/0008-5472.22410347
Autor:
David N. Wald, Yogen Saunthararajah, Gary Parizher, Stephen Moreton, James Ignatz-Hoover, Tammy Stefan, Kalpana Gupta
Western blot control for JNK inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8c80e75ef249ae1b5bccf3f689d68b
https://doi.org/10.1158/0008-5472.22410353
https://doi.org/10.1158/0008-5472.22410353
Autor:
Banumathi Tamilselvan, Zachary Jackson, Susan Pereira Ribeiro, Jill S. Barnholtz-Sloan, Jaroslaw P. Maciejewski, David N. Wald, Kalpana Gupta, Ashish Sharma, Xuan Xu, Rafick-Pierre Sekaly, Robert Schauner, Anne Roe, Samuel Li, Robert S. Balderas, Tae Hyun Hwang, Lindsay Stetson, Slim Fourati, Marcos de Lima, Thomas LaFramboise, Dheepa Balasubramanian, Yogen Saunthararajah, Tammy Stefan
Publikováno v:
Leukemia
The prognosis of most patients with AML is poor due to frequent disease relapse. The cause of relapse is thought to be from the persistence of leukemia initiating cells (LIC's) following treatment. Here we assessed RNA based changes in LICs from matc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a602a1f29de6b5360b3e7daf3b3d7d
https://doi.org/10.1038/s41375-021-01338-7
https://doi.org/10.1038/s41375-021-01338-7
Publikováno v:
Flow Cytometry Protocols ISBN: 9781493973446
Cell cycle cytometry and analysis are essential tools for studying cells of model organisms and natural populations (e.g., bone marrow). Methods have not changed much for many years. The simplest and most common protocol is DNA content analysis, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa6b0a76af0434692846899bf08d66b
https://doi.org/10.1007/978-1-4939-7346-0_11
https://doi.org/10.1007/978-1-4939-7346-0_11
Publikováno v:
Cell Cycle. 7:1285-1300
Cyclin B1 should have some rate limiting function for cell cycle progression. To test this, we measured the effect of siRNA-mediated depletion of cyclin B1 on mitotic entry and timing. We depleted cyclin B1 in HeLa and hTert-RPE1 cells to levels equi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669adf0df1a848967785adfbde507d60
https://doi.org/10.4161/cc.7.9.5711
https://doi.org/10.4161/cc.7.9.5711
Autor:
Tammy Stefan, Keith Shults, Deena V. Soni, James W. Jacobberger, R. Michael Sramkoski, Phyllis S. Frisa
Publikováno v:
Cytometry Part A. :5-15
Many epitopes are phosphorylated during mitosis. These epitopes are useful biomarkers for mitotic cells. The most commonly used are MPM-2 and serine 10 of histone H3. Here we investigated the use of an antibody generated against a phospho peptide mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3921df1462a58062e2db4d80f8163d
https://doi.org/10.1002/cyto.a.20501
https://doi.org/10.1002/cyto.a.20501