Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Tammy M, Havener"'
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11870-11882 (2024)
Externí odkaz:
https://doaj.org/article/f3c6859e6bc74430b547d98abc8ab94e
Autor:
Han Wee Ong, Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander, Tammy M. Havener, Marcia K. Sanders, Jason W. Brown, Rafael M. Couñago, Edcon Chang, Andreas Krämer, Nathaniel J. Moorman, Mark Heise, Alison D. Axtman, David H. Drewry, Timothy M. Willson
Publikováno v:
Molecules, Vol 29, Iss 17, p 4158 (2024)
The host kinase casein kinase 2 (CSNK2) has been proposed to be an antiviral target against β-coronaviral infection. To pharmacologically validate CSNK2 as a drug target in vivo, potent and selective CSNK2 inhibitors with good pharmacokinetic proper
Externí odkaz:
https://doaj.org/article/62c77468b14449aaab38290f68c9e3ba
Autor:
George W. Small, Farida S. Akhtari, Adrian J. Green, Tammy M. Havener, Michael Sikes, Julia Quintanhila, Ricardo D. Gonzalez, David M. Reif, Alison A. Motsinger-Reif, Howard L. McLeod, Tim Wiltshire
Publikováno v:
Cells, Vol 12, Iss 12, p 1574 (2023)
Monoclonal antibody (mAb) therapy directed against CD20 is an important tool in the treatment of B cell disorders. However, variable patient response and acquired resistance remain important clinical challenges. To identify genetic factors that may i
Externí odkaz:
https://doaj.org/article/fc45090c563c425fbc7ecb27e7e70be1
Autor:
Ricardo D. Gonzalez, George W. Small, Adrian J. Green, Farida S. Akhtari, Tammy M. Havener, Julia C. F. Quintanilha, Amber B. Cipriani, David M. Reif, Howard L. McLeod, Alison A. Motsinger-Reif, Tim Wiltshire
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 726 (2023)
Temozolomide (TMZ) chemotherapy is an important tool in the treatment of glioma brain tumors. However, variable patient response and chemo-resistance remain exceptionally challenging. Our previous genome-wide association study (GWAS) identified a sug
Externí odkaz:
https://doaj.org/article/57e65b5154c4450e9438e8a07a74bd2b
Autor:
Ricardo D. Gonzalez, George W. Small, Adrian J. Green, Farida S. Akhtari, Alison A. Motsinger-Reif, Julia C. F. Quintanilha, Tammy M. Havener, David M. Reif, Howard L. McLeod, Tim Wiltshire
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 757 (2023)
Oxaliplatin (OXAL) is a commonly used chemotherapy for treating colorectal cancer (CRC). A recent genome wide association study (GWAS) showed that a genetic variant (rs11006706) in the lncRNA gene MKX-AS1 and partnered sense gene MKX could impact the
Externí odkaz:
https://doaj.org/article/8aa3c245cb8d4f288b8d1ffcb9ff9422
Autor:
Farida S Akhtari, Adrian J Green, George W Small, Tammy M Havener, John S House, Kyle R Roell, David M Reif, Howard L McLeod, Timothy Wiltshire, Alison A Motsinger-Reif
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009732 (2021)
Cancer patients exhibit a broad range of inter-individual variability in response and toxicity to widely used anticancer drugs, and genetic variation is a major contributor to this variability. To identify new genes that influence the response of 44
Externí odkaz:
https://doaj.org/article/f1416aa594d345ff9d7fa52334c49271
Autor:
Zachary W. Davis-Gilbert, Andreas Krämer, James E. Dunford, Stefanie Howell, Filiz Senbabaoglu, Carrow I. Wells, Frances M. Bashore, Tammy M. Havener, Jeffery L. Smith, Mohammad A. Hossain, Udo Oppermann, David H. Drewry, Alison D. Axtman
Publikováno v:
ACS Medicinal Chemistry Letters. 14:432-441
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c8409e0512fd44b783dd45f86d23ef
https://doi.org/10.1021/acsmedchemlett.2c00530
https://doi.org/10.1021/acsmedchemlett.2c00530
Autor:
Kareem A. Galal, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy M. Havener, Michael E. Chirgwin, Eric Merten, Han Wee Ong, Caleb Willis, Ahmad Abdelwaly, Mohamed A. Helal, Emily R. Derbyshire, Reena Zutshi, David H. Drewry
Publikováno v:
Journal of Medicinal Chemistry. 65:13172-13197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9157dae09bb16f8beecc10edc94755ec
https://doi.org/10.1021/acs.jmedchem.2c00996
https://doi.org/10.1021/acs.jmedchem.2c00996
Autor:
Kyle R. Roell, Tammy M. Havener, David M. Reif, John Jack, Howard L. McLeod, Tim Wiltshire, Alison A. Motsinger-Reif
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Lymphoblastoid cell lines (LCLs) are a highly successful model for evaluating the genetic etiology of cancer drug response, but applications using this model have typically focused on single drugs. Combination therapy is quite common in modern chemot
Externí odkaz:
https://doaj.org/article/9f04ec0542dc4709902de0da0c28679f
Autor:
Wiltshire, George W. Small, Farida S. Akhtari, Adrian J. Green, Tammy M. Havener, Michael Sikes, Julia Quintanhila, Ricardo D. Gonzalez, David M. Reif, Alison A. Motsinger-Reif, Howard L. McLeod, Tim
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1574
Monoclonal antibody (mAb) therapy directed against CD20 is an important tool in the treatment of B cell disorders. However, variable patient response and acquired resistance remain important clinical challenges. To identify genetic factors that may i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::60218ec289bf97ce7c7fd0873c0f1f70