Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tammy Jessen"'
Publikováno v:
Neurobiology of Stress, Vol 2, Iss C, Pp 51-58 (2015)
Recent studies indicate multiple roles for integrin αvβ3 in adult neurons, including response to pharmacological agents such as cocaine and selective serotonin reuptake inhibitors. In this study, we examined the role of the integrin β3 gene (Itgb3
Externí odkaz:
https://doaj.org/article/f0680d52354e4f47b959b889fa644ee5
Autor:
Lisa Bastarache, Ana Carneiro, Capria Rinaldi, James S. Sutcliffe, Matthew D. Mazalouskas, Seth Varney, Michael R. Dohn, Digna R. Velez Edwards, Tammy Jessen, Joshua C. Denny, Christopher G. Kooker, Kendra H. Oliver, Hope Pan
Publikováno v:
The Journal of Neuroscience. 37:11271-11284
Engagement of integrins by the extracellular matrix initiates signaling cascades that drive a variety of cellular functions, including neuronal migration and axonal pathfinding in the brain. Multiple lines of evidence link theITGB3gene encoding the i
Publikováno v:
Neurobiology of Stress
Neurobiology of Stress, Vol 2, Iss C, Pp 51-58 (2015)
Neurobiology of Stress, Vol 2, Iss C, Pp 51-58 (2015)
Recent studies indicate multiple roles for integrin αvβ3 in adult neurons, including response to pharmacological agents such as cocaine and selective serotonin reuptake inhibitors. In this study, we examined the role of the integrin β3 gene (Itgb3
Autor:
Seth Varney, Tammy Jessen, Edwin H. Cook, James S. Sutcliffe, Ana Carneiro, Jeremy Veenstra-VanderWeele, Matthew D. Mazalouskas
Publikováno v:
Neuropsychopharmacology. 40:2015-2024
Converging lines of evidence have identified genetic interactions between the serotonin transporter (SERT) gene and ITGB3, which encodes the β3 subunit that forms the αIIbβ3 and αvβ3 integrin receptor complexes. Here we examine the consequences
Autor:
Ana Carneiro, Elaine Sanders-Bush, Charisma R. Shah, W. Anthony Owens, Brent J. Thompson, Hideki Iwamoto, Ran Ye, Jennifer E. Sauer, Padmanabhan Mannangatti, Douglas G. McMahon, James S. Sutcliffe, Jordan Cohen, Lynette C. Daws, Randy D. Blakely, Jacqueline N. Crawley, Christopher L. Muller, Travis M. Kerr, Sammanda Ramamoorthy, Jeremy Veenstra-VanderWeele, Tammy Jessen
Publikováno v:
Proceedings of the National Academy of Sciences. 109:5469-5474
Fifty years ago, increased whole-blood serotonin levels, or hyperserotonemia, first linked disrupted 5-HT homeostasis to Autism Spectrum Disorders (ASDs). The 5-HT transporter (SERT) gene ( SLC6A4 ) has been associated with whole blood 5-HT levels an
Autor:
Lucia Carvelli, Richard Nass, Paul W. McDonald, Tammy Jessen, Maureen K. Hahn, Randy D. Blakely
Publikováno v:
Journal of Neurochemistry. 94:774-785
The presynaptic dopamine (DA) transporter (DAT) is a major determinant of synaptic DA inactivation, an important target for psychostimulants including cocaine and amphetamine, and a mediator of DA neuron vulnerability to the neurotoxins 6-hydroxydopa
Autor:
Emily L. Crawford, Chang Y. Chung, Ana Carneiro, James S. Sutcliffe, Kendra H. Oliver, Tammy Jessen
The plasma-membrane integrin αIIbβ3 (CD41/CD61, GPIIbIIIa) is a major functional receptor in platelets during clotting. A common isoform of integrin β3, Leu33Pro is associated with enhanced platelet function and increased risk for coronary thrombo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefdcca94cede8e00639834598925d26
https://europepmc.org/articles/PMC4014669/
https://europepmc.org/articles/PMC4014669/
Autor:
Gregg D. Stanwood, Marc A. Mergy, Jane Wright, Randy D. Blakely, Raajaram Gowrishankar, Tammy Jessen, Maureen K. Hahn, Gwynne L. Davis
Publikováno v:
Neurochemistry international. 73
Alterations in dopamine (DA) signaling underlie the most widely held theories of molecular and circuit level perturbations that lead to risk for attention-deficit hyperactivity disorder (ADHD). The DA transporter (DAT), a presynaptic reuptake protein
SEROTONIN TRANSPORTER AND INTEGRIN BETA 3 GENES INTERACT TO MODULATE SEROTONIN UPTAKE IN MOUSE BRAIN
Dysfunctions in serotonin (5-hydroxytryptamine, 5-HT) systems have been associated with several psychiatric illnesses, including anxiety, depression, obsessive-compulsive disorders and autism spectrum disorders. Convergent evidence from genetic analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af651c072178540b7772a9b1a03f62ee
https://europepmc.org/articles/PMC3969782/
https://europepmc.org/articles/PMC3969782/
Autor:
Yekaterina Belova, Rebecca E. Horton, Randy D. Blakely, Lynette C. Daws, Peter J. Chisnell, Karen L. Gamble, Julie R. Field, Tammy Jessen, Brent J. Thompson, Paul J. Gresch, Ana Carneiro, Douglas G. McMahon, L. K. Henry
Serotonin [i.e., 5-hydroxytryptamine (5-HT)]–targeted antidepressants are in wide use for the treatment of mood disorders, although many patients do not show a response or experience unpleasant side effects. Psychostimulants, such as cocaine and 3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0acf22d0ee741c0d7681a2a04ba1731
https://europepmc.org/articles/PMC3048100/
https://europepmc.org/articles/PMC3048100/