Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tammy B. DeHahn"'
Autor:
Margaret M. Faul, Christine A. Kumrich, Bryan A. Anderson, Concha Sanchez-Martinez, Tammy B. DeHahn, Harold B. Brooks, Catherine A. Ogg, Michael Paal, Robert M. Campbell, Carmen Somoza, Tiechao Li, Leonard L. Winneroski, Bharvin K. R. Patel, Chuan Shih, Zhou Xun, Jill R. Wagner, Eileen L. Considine, Guoxin Zhu, Scott A. Watkins, Jack A. Dempsey, Richard M. Schultz, Charles D. Spencer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:3835-3839
The synthesis of new analogues of Arcyriaflavin A in which one indole ring is replaced by an aryl or heteroaryl ring is described. These new series of aryl[a]pyrrolo[3,4-c]carbazoles were evaluated as inhibitors of Cyclin D1-CDK4. A potent and select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df687a4b3b53d0840e632261b56272e
https://doi.org/10.1016/s0960-894x(03)00791-1
https://doi.org/10.1016/s0960-894x(03)00791-1
Autor:
Concha Sanchez-Martinez, Chuan Shih, Richard M. Schultz, Guoxin Zhu, Charles D. Spencer, Tiechao Li, Catherine A. Ogg, Bharvin K. R. Patel, Eileen L. Considine, Jack A. Dempsey, Faming Zhang, Harold B. Brooks, Tammy B. DeHahn, Scott A. Watkins
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:3841-3846
A series of indolo[2,3-a]pyrrolo[3,4-c]carbazoles and their bis-indolylmaleimides precursors have been prepared in order to compare their activity as D1-CDK4 inhibitors. Both enzymatic and antiproliferative assays have shown that the structurally mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859dd25d9a43bc2311db2a97d9975f4c
https://doi.org/10.1016/s0960-894x(03)00792-3
https://doi.org/10.1016/s0960-894x(03)00792-3
Autor:
Thomas A. Engler, Sushant Malhotra, Catherine A. Ogg, Nancy B. Stamm, Kevin A. Sullivan, Kelly Wayne Furness, Bharvin K. R. Patel, Kashif Kirmani, Scott Eugene Conner, Jack A. Dempsey, Eileen L. Considine, Concha Sanchez-Martinez, Guoxin Zhu, Michelle L. Lytle, Stanley P. Kolis, Walter Xie, Tammy B. DeHahn, Vasu Vasudevan, Robert M. Campbell, Chuan Shih, Bryan D. Anderson, Xun Zhou, Scott A. Watkins, Richard M. Schultz, Charles D. Spencer, Margaret M. Faul, Harold B. Brooks
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(14)
The synthesis and CDK inhibitory properties of a series of indolo[6,7-a]pyrrolo[3,4-c]carbazoles is reported. In addition to their potent CDK activity, the compounds display antiproliferative activity against two human cancer cell lines. These inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f798cc8a3dc2f617e6008c991c03d4c
https://pubmed.ncbi.nlm.nih.gov/12824014
https://pubmed.ncbi.nlm.nih.gov/12824014