Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Tammy, Kielian"'
Autor:
Lee E. Korshoj, Tammy Kielian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Biofilm formation is an important mechanism of survival and persistence for many bacterial pathogens. These multicellular communities contain subpopulations of cells that display metabolic and transcriptional diversity along with recalcitran
Externí odkaz:
https://doaj.org/article/2d2976da176f492aa4149d8dd0474b1e
Autor:
Zachary Van Roy, Prabakar Arumugam, Blake P. Bertrand, Dhananjay D. Shinde, Vinai C. Thomas, Tammy Kielian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Infection is a devastating post-surgical complication, often requiring additional procedures and prolonged antibiotic therapy. This is especially relevant for craniotomy and prosthetic joint infections (PJI), both of which are characterized
Externí odkaz:
https://doaj.org/article/b9cb3c1ff84d4d3fa443a10ad71a822a
Autor:
Zachary Van Roy, Tammy Kielian
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Craniotomy is a common neurosurgery used to treat intracranial pathologies. Nearly 5% of the 14 million craniotomies performed worldwide each year become infected, most often with Staphylococcus aureus (S. aureus), which forms a b
Externí odkaz:
https://doaj.org/article/5bd76b8ce0d94773a4c1078baf7b725b
Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures
Autor:
Aaron D. Schwab, Amy J. Nelson, Angela M. Gleason, Oliver W. Schanze, Todd A. Wyatt, Dhananjay D. Shinde, Peng Xiao, Vinai C. Thomas, Chittibabu Guda, Kristina L. Bailey, Tammy Kielian, Geoffrey M. Thiele, Jill A. Poole
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundEnvironmental lipopolysaccharide (LPS) and microbial component-enriched organic dusts cause significant lung disease. These environmental exposures induce the recruitment and activation of distinct lung monocyte/macrophage subpopulations in
Externí odkaz:
https://doaj.org/article/086fbe7825ba451eb94481bbeca9982e
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSignificant neurologic morbidity is caused by pediatric cerebrospinal fluid (CSF) shunt infections. The underlying mechanisms leading to impaired school performance and increased risk of seizures are unknown, however, a better understandi
Externí odkaz:
https://doaj.org/article/189c04e46daa44639b3129b17831f05e
Autor:
Gunjan Kak, Zachary Van Roy, Cortney E. Heim, Rachel W. Fallet, Wen Shi, Axel Roers, Bin Duan, Tammy Kielian
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Treatment of brain tumors, epilepsy, or hemodynamic abnormalities requires a craniotomy to access the brain. Nearly 1 million craniotomies are performed in the US annually, which increase to ~ 14 million worldwide and despite prop
Externí odkaz:
https://doaj.org/article/1505c202b9694fa688fdb06b51be8adf
Autor:
Ryan M. Singh, Sujata S. Chaudhari, Sasmita Panda, Elizabeth H. Hutfless, Cortney E. Heim, Dhananjay Shinde, Abdulelah A. Alqarzaee, Margaret Sladek, Vineet Kumar, Matthew C. Zimmerman, Paul D. Fey, Tammy Kielian, Vinai C. Thomas
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102935- (2023)
Most coagulase-negative staphylococcal species, including the opportunistic pathogen Staphylococcus epidermidis, struggle to maintain redox homeostasis and grow under nitrosative stress. Under these conditions, growth can only resume once nitric oxid
Externí odkaz:
https://doaj.org/article/8d1bfec481d548bda7212dd3f2098cab
Autor:
Prabhakar Arumugam, Tammy Kielian
Publikováno v:
Journal of Innate Immunity, Pp 1-1 (2023)
Background: Staphylococcus aureus (S. aureus) is a common cause of hospital- and community-acquired infections that can result in various clinical manifestations ranging from mild to severe disease. The bacterium utilizes different combinations of vi
Externí odkaz:
https://doaj.org/article/2033bb60077c4743a89531379e302f5a
Autor:
Matthew Beaver, Dragana Noe, Ishwor Thapa, Hesham Ali, Jessica Snowden, Tammy Kielian, Gwenn L. Skar
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundCerebrospinal fluid (CSF) shunt infection is a common and devastating complication of the treatment of hydrocephalus. Timely and accurate diagnosis is essential as these infections can lead to long-term neurologic consequences including sei
Externí odkaz:
https://doaj.org/article/8249b2de294f45c5abedc80d2d98d60c
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-17 (2020)
Abstract Background A craniotomy is required to access the brain for tumor resection or epilepsy treatment, and despite precautionary measures, infectious complications occur at a frequency of 1–3%. Approximately half of craniotomy infections are c
Externí odkaz:
https://doaj.org/article/e63b9708c3d84fb385c1c48a535b7745