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Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse

Autor: Taavitsainen, S., Engedal, N., Cao, S., Handle, F., Erickson, A., Prekovic, S., Wetterskog, D., Tolonen, T., Vuorinen, E. M., Kiviaho, A., Nätkin, R., Häkkinen, T., Devlies, W., Henttinen, S., Kaarijärvi, R., Lahnalampi, M., Kaljunen, H., Nowakowska, K., Syvälä, H., Bläuer, M., Cremaschi, P., Claessens, F., Visakorpi, T., Tammela, T. L. J., Murtola, T., Granberg, K. J., Lamb, A. D., Ketola, K., Mills, I. G., Attard, G., Wang, W., Nykter, M., Urbanucci, A.

Publikováno v: Taavitsainen, S, Engedal, N, Cao, S, Handle, F, Erickson, A, Prekovic, S, Wetterskog, D, Tolonen, T, Vuorinen, E M, Kiviaho, A, Nätkin, R, Häkkinen, T, Devlies, W, Henttinen, S, Kaarijärvi, R, Lahnalampi, M, Kaljunen, H, Nowakowska, K, Syvälä, H, Bläuer, M, Cremaschi, P, Claessens, F, Visakorpi, T, Tammela, T L J, Murtola, T, Granberg, K J, Lamb, A D, Ketola, K, Mills, I G, Attard, G, Wang, W, Nykter, M & Urbanucci, A 2021, ' Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse ', Nature Communications, vol. 12, no. 1 . https://doi.org/10.1038/s41467-021-25624-1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. Here, we employ single-cell assays for transposase-accessible chromatin (ATAC) and RNA sequencing in models of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::66dd98a7ed2dc0560613c76ad1776551
https://lirias.kuleuven.be/handle/123456789/682242

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False-positive screening results in the Finnish prostate cancer screening trial.

Autor: Kilpeläinen, T. P.^1,2 tuomas.kilpelainen@uta.fi, Tammela, T. L. J.¹, Määttänen, L.³, Kujala, P.⁴, Stenman, U.-H.⁵, Ala-Opas, M.⁶, Murtola, T. J.^2,7, Auvinen, A.², Kilpeläinen, T P⁸ (AUTHOR), Määttänen, L (AUTHOR)

Publikováno v: British Journal of Cancer. 2/10/2010, Vol. 102 Issue 3, p469-474. 6p. 3 Charts.

C-reactive protein haplotype is associated with high PSA as a marker of metastatic prostate cancer but not with overall cancer risk.

Autor: Eklund, C. M.¹ carita.eklund@uta.fi, Tammela, T. L. J.², Schleutker, J.³, Hurme, M.^1,4

Publikováno v: British Journal of Cancer. 6/16/2009, Vol. 100 Issue 12, p1846-1851. 6p. 3 Charts.