Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tamir Dingjan"'
Autor:
Tamir Dingjan, Anthony H. Futerman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Biological membranes consist of a lipid bilayer in which integral membrane proteins are embedded. Based on the compositional complexity of the lipid species found in membranes, and on their specific and selective interactions with membrane proteins,
Externí odkaz:
https://doaj.org/article/e49b5d3597bb40b7af78f852067fbdcc
Autor:
Iris D. Zelnik, Beatriz Mestre, Jonathan J. Weinstein, Tamir Dingjan, Stav Izrailov, Shifra Ben-Dor, Sarel J. Fleishman, Anthony H. Futerman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-6 (2023)
Abstract Until now, membrane-protein stabilization has relied on iterations of mutations and screening. We now validate a one-step algorithm, mPROSS, for stabilizing membrane proteins directly from an AlphaFold2 model structure. Applied to the lipid-
Externí odkaz:
https://doaj.org/article/014e0396f55e4922b17b62df905dfa74
Autor:
Shani Blumenreich, Tamar Nehushtan, Or B. Barav, Jennifer T. Saville, Tamir Dingjan, John Hardy, Maria Fuller, Anthony H. Futerman
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract A number of genetic risk factors have been identified over the past decade for Parkinson’s Disease (PD), with variants in GBA prominent among them. GBA encodes the lysosomal enzyme that degrades the glycosphingolipid, glucosylceramide (Glc
Externí odkaz:
https://doaj.org/article/eef8903ef3da4d92af2541024a5a2e06
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Burkholderia ambifaria is an opportunistic respiratory pathogen belonging to the Burkholderia cepacia complex, a collection of species responsible for the rapidly fatal cepacia syndrome in cystic fibrosis patients. A fucose-binding lectin identified
Externí odkaz:
https://doaj.org/article/48d39b4434a44d81ad3a8ba415369689
Autor:
Alexander Titz, Elizabeth Yuriev, Emilie Gillon, Paul A. Ramsland, Serge Pérez, Anne Imberty, Tamir Dingjan
Publikováno v:
Journal of chemical information and modeling
Journal of Chemical Information and Modeling
Journal of Chemical Information and Modeling, American Chemical Society, 2018, 58 (9), pp.1976-1989. ⟨10.1021/acs.jcim.8b00185⟩
Journal of Chemical Information and Modeling
Journal of Chemical Information and Modeling, American Chemical Society, 2018, 58 (9), pp.1976-1989. ⟨10.1021/acs.jcim.8b00185⟩
Bacterial adhesion to human epithelia via lectins constitutes a therapeutic opportunity to prevent infection. Specifically, BambL (the lectin from Burkholderia ambifaria) is implicated in cystic fibrosis, where lectin-mediated bacterial adhesion to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ba1dc243139829e9f736525adb1c14
Autor:
Fabrizio Fierro, Lior Peri, Harald Hübner, Alina Tabor-Schkade, Lukas Waterloo, Stefan Löber, Tara Pfeiffer, Dorothee Weikert, Tamir Dingjan, Eitan Margulis, Peter Gmeiner, Masha Y Niv
The human GPCR family comprises circa 800 members, activated by hundreds of thousands of compounds. Bitter taste receptors, TAS2Rs, constitute a large and distinct subfamily, expressed orally and extra-orally and involved in physiological and patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96884d8fe3235810ce0c5cc917b7a62
https://doi.org/10.1101/2022.11.24.517821
https://doi.org/10.1101/2022.11.24.517821
Publikováno v:
FEBS lettersReferences. 596(18)
Modern cell membranes contain a bewildering complexity of lipids, among them sphingolipids (SLs). Advances in mass spectrometry have led to the realization that the number and combinatorial complexity of lipids, including SLs, is much greater than pr
Autor:
Ann-Katrin Holik, Mark M. Somoza, Veronika Somoza, Joachim Hans, Kathrin Hölz, Verena Stoeger, Jakob Ley, Masha Y. Niv, Tamir Dingjan, Gerhard Krammer
Publikováno v:
Journal of Agricultural and Food Chemistry. 68:3434-3444
This study aimed at identifying whether the bitter-tasting amino acids l-arginine (l-ARG) and l-isoleucine (l-ILE) differentially regulate mechanisms of gastric acid secretion in human parietal cells (HGT-1 cells) via activation of bitter taste sensi
Autor:
Tamir Dingjan, Fyodor Tatarinov, Eyal Rotenberg, Abraham Kribus, Jonathan D. Muller, Irina Vishnevetsky, Dan Yakir
Temperature is a key control over biological activities from the cellular to the ecosystem scales. However, direct, high precision measurements of surface temperature of small objects such as leaves under field conditions with large variations in amb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14f1626afa2375acbd50c46fd64b507
https://doi.org/10.1101/2021.04.25.440729
https://doi.org/10.1101/2021.04.25.440729
Autor:
Tamir Dingjan, Anthony H. Futerman
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biologyREFERENCES. 43(5)
Cell membranes are now emerging as finely tuned molecular systems, signifying that re-evaluation of our understanding of their structure is essential. Although the idea that cell membrane lipid bilayers do little more than give shape and form to cell