Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tamir Diamond"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Hemophagocytic Lymphohistiocytosis (HLH) is a group of disorders culminating in systemic inflammation and multi-organ failure with high incidence of hepatic dysfunction. Overproduction of IFN-γ is the main immunopathological driver in this
Externí odkaz:
https://doaj.org/article/c2543beaef8b42f9b457cd7c5c1d0059
Autor:
Kapish Gupta, Jimmy P Xu, Tamir Diamond, Iris E M de Jong, Andrew Glass, Jessica Llewellyn, Neil D Theise, Orith Waisbourd-Zinman, Jeffrey D Winkler, Edward M Behrens, Clementina Mesaros, Rebecca G Wells
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301824 (2024)
Biliary atresia is a neonatal disease characterized by damage, inflammation, and fibrosis of the liver and bile ducts and by abnormal bile metabolism. It likely results from a prenatal environmental exposure that spares the mother and affects the fet
Externí odkaz:
https://doaj.org/article/74507efcbeca4a1daf62e83fff6e33fb
Autor:
Catherine A Chapin, Thomas M Burn, Tamir Diamond, Kathleen M Loomes, Estella M Alonso, Edward M Behrens
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286394 (2023)
A distinct phenotype of pediatric acute liver failure (PALF) has been identified, labeled activated T-cell hepatitis. These patients, previously included within the indeterminate group, have evidence of systemic immune activation and liver biopsy spe
Externí odkaz:
https://doaj.org/article/9d4b7210c09a457e93765223814102db
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 144-145 (2023)
OBJECTIVES/GOALS: Familial Hemophagocytic Lymphohistiocytosis (FHL) is a systemic inflammatory disease, causing acute liver failure (ALF). Elevated Interferon gamma (IFN-γ) results in increased hepatic transcription of the chemokines CXCL9 and CXCL1
Externí odkaz:
https://doaj.org/article/cc39c99c97fc440b97e01780e8499d81
Autor:
Tamir Diamond, Thomas N. Burn, Mailyn A. Nishiguchi, Danielle Minichino, Julie Chase, Niansheng Chu, Portia A. Kreiger, Edward M. Behrens
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Interferon gamma (IFN-γ) is the main cytokine driving organ dysfunction in Familial Hemophagocytic Lymphohistiocytosis (FHL). Blockade of IFN-γ pathway ameliorates FHL hepatitis, both in animal models and in humans with FHL. Hepatocytes are known t
Externí odkaz:
https://doaj.org/article/b02e6289a6744fb1838f28b7bc233c34
Autor:
Catherine A Chapin, Tamir Diamond, Rebecca M Harris, Olivia Vaccaro, Kathleen M Loomes, Estella M Alonso, Edward M Behrens
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e49a74d8d5ec4e0583d866cc05089f0
https://doi.org/10.1097/mpg.0000000000003851
https://doi.org/10.1097/mpg.0000000000003851
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c56b68ea3c67c31bde96a3d4473350
https://doi.org/10.1097/mpg.0000000000003807
https://doi.org/10.1097/mpg.0000000000003807
Autor:
Kapish Gupta, Jimmy P. Xu, Tamir Diamond, Iris De Jong, Andrew Glass, Jessica Llewellyn, Neil D. Theise, Jeffrey D. Winkler, Edward M. Behrens, Clementina Mesaros, Rebecca G. Wells
Background & AimsBiliary atresia is a neonatal disease characterized by bile duct and liver damage, fibrosis, inflammation and abnormal bile metabolism. It appears to result from a prenatal exposure that spares the mother and affects the fetus. Our a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645ec5fd81d29f6607add99a95ae9e63
https://doi.org/10.1101/2023.03.02.530913
https://doi.org/10.1101/2023.03.02.530913
Autor:
Alanna Strong, Soumya Rao, Sandra von Hardenberg, Dong Li, Liza L. Cox, Paul C. Lee, Li Q. Zhang, Waheed Awotoye, Tamir Diamond, Jessica Gold, Catherine Gooch, Lord Jephthah Joojo Gowans, Hakon Hakonarson, Anne Hing, Kathleen Loomes, Nicole Martin, Mary L. Marazita, Tarja Mononen, David Piccoli, Rolph Pfundt, Salmo Raskin, Stephen W. Scherer, Nara Sobriera, Courtney Vaccaro, Xiang Wang, Deborah Watson, Rosanna Weksberg, Elizabeth Bhoj, Jeffrey C. Murray, Andrew C. Lidral, Azeez Butali, Michael F. Buckley, Tony Roscioli, David A. Koolen, Laurie H. Seaver, Cynthia A. Prows, Rolf W. Stottmann, Timothy C. Cox
Publikováno v:
American Journal of Medical Genetics. Part A, 191, 1227-1239
American Journal of Medical Genetics. Part A, 191, 5, pp. 1227-1239
American Journal of Medical Genetics. Part A, 191, 5, pp. 1227-1239
Contains fulltext : 291896.pdf (Publisher’s version ) (Closed access) AMOTL1 encodes angiomotin-like protein 1, an actin-binding protein that regulates cell polarity, adhesion, and migration. The role of AMOTL1 in human disease is equivocal. We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23284fd34032c2478d215b0eced1113d
http://hdl.handle.net/2066/291896
http://hdl.handle.net/2066/291896
Autor:
Cuiping Hou, Kathleen M. Loomes, Erum A. Hartung, Diana J. Slater, Tamir Diamond, Courtney Vaccaro, Sanmati Cuddapah, Alanna Strong, Evelyn K. Shih, Anne Marie Cahill, Gina O'Grady, Deborah Watson, Jonathan R Bishop, Hakon Hakonarson, Dong Li, William Wong
Publikováno v:
American Journal of Medical Genetics. Part a
Ring‐finger protein 213 (RNF213) encodes a protein of unknown function believed to play a role in cellular metabolism and angiogenesis. Gene variants are associated with susceptibility to moyamoya disease. Here, we describe two children with moyamo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d724d2e39535cb50d720613cd03bd2
https://doi.org/10.1002/ajmg.a.62215
https://doi.org/10.1002/ajmg.a.62215