Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tamiki Mori"'
Autor:
Rui Ohashi, Takahiro Nakamura, Yoshiro Saito, Kosuke Saito, Seiji Tanaka, Masaaki Kakehi, Tamiki Mori, Hiroyuki Kakuo, Ryosuke Nakamura, Mizuki Horiuchi, Hiroyuki Yokoi, Harue Igarashi, Hiroyuki Shimizu, Masataka Katashima, Yoshiaki Ohtsu, Yutaka Yasuda, Takashige Okayama
Publikováno v:
Bioanalysis. 13(18)
Biomarkers are an important drug developmental tool. Assessment of quantitative analytical methods of biomarkers is not included in any regulatory documents in Japan. Use of biomarkers in clinical evaluations and supporting the post-marketing evaluat
Autor:
Noriko Katori, Jun Hosogi, Kenta Kadotsuji, Kazuhiro Nishimiya, Tamiki Mori, Masako Soma, Kyoko Minoura, Muneo Aoyama, Tatsuki Nomura, Hiroko Shibata, Hiroki Wakabayashi, Takahiro Nakamura, Kazuko Nishimura, Akiko Ishii-Watabe, Yoshiro Saito, Norihisa Sakamoto, Shingo Niimi, Tetsu Saito
Publikováno v:
Bioanalysis. 11:509-524
Aim: Appropriateness of anti-drug antibody (ADA) assay is critical for immunogenicity assessment of biopharmaceuticals. Although cut point setting in ADA assay has a large impact on the results, a standard statistical approach for its setting has not
Autor:
Tadashi Kumagai, Tokuhisa Hirouchi, Tamiki Mori, Hiroshi Morioka, Mika Teranishi, Ayumi Yamamoto, Jun Hidema, Kazuo Yamamoto
Publikováno v:
Genes & Genetic Systems. 82:311-319
Class I and class II CPD photolyases are enzymes which repair pyrimidine dimers using visible light. A detailed characterization of class I CPD photolyases has been carried out, but little is known about the class II enzymes. Photolyases from rice ar
Autor:
Takayuki Ozaki, Yukio Fujita, Hiroshi Enomoto, Tamiki Mori, Yoshiaki Yoshikuni, Kenji Sempuku, Akio Ogino, Masahiro Kise, Tomoko Sotomatsu
Publikováno v:
Chemical and Pharmaceutical Bulletin. 39:1193-1198
A series of N-phenyl-delta 8-dihydroabietamide analogs were prepared and tested for hypocholesterolemic activity. The effects of substituents of the phenyl moiety on the activities were quantitatively analyzed by using various substituent parameters.
Autor:
Kenji Sempuku, Yasuo Yasutomi, Tamiki Mori, Yukio Fujita, Katsuya Ohata, Koji Kitaguchi, Yoshiaki Yoshikuni, Hiroshi Enomoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 25:507-510
Various tricyclic diterpenoid derivatives of totarol, abietane and pimarane groups were found to have serum cholesterol lowering action in rats. Inhibition of intestinal cholesterol absorption was suggested to be involved in the main mechanism of hyp
Autor:
Roland Loser, Tamiki Mori, Hiroshi Enomoto, Koji Kitaguchi, Hiromu Murai, Kenji Sempuku, Yoshiaki Yoshikuni, Yukio Fujita
Publikováno v:
Chemicalpharmaceutical bulletin. 28(2)
Various amides of tetrahydroabietic, Δ8-dihydroabietic, abietic and dehydroabietic acids were prepared and tested for hypocholesterolemic activity in cholesterol-fed rats. The introduction of an aromatic ring into the amine moiety of secondary amide