Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tamer al-Maghout"'
Autor:
Basma Sukkar, Stefan Hauser, Lisann Pelzl, Zohreh Hosseinzadeh, Itishri Sahu, Tamer al-Maghout, Abdulla Al Mamun Bhuyan, Nefeli Zacharopoulou, Christos Stournaras, Ludger Schöls, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 1, Pp 278-289 (2018)
Background/Aims: The neurodegenerative disease Chorea-Acanthocytosis (ChAc) is caused by loss-of-function-mutations of the chorein-encoding gene VPS13A. In ChAc neurons transcript levels and protein abundance of Ca2+ release activated channel moiety
Externí odkaz:
https://doaj.org/article/078d7e4617df442498d11d43d0b718c1
Autor:
Tamer Al-Maghout, Lisann Pelzl, Itishri Sahu, Basma Sukkar, Zohreh Hosseinzadeh, Ravi Gutti, Stefan Laufer, Jakob Voelkl, Burkert Pieske, Meinrad Gawaz, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 6, Pp 2169-2181 (2017)
Background: TGFβ1, a decisive regulator of megakaryocyte maturation and platelet formation, has previously been shown to up-regulate both, store operated Ca2+ entry (SOCE) and Ca2+ extrusion by Na+/Ca2+ exchange. The growth factor thus augments the
Externí odkaz:
https://doaj.org/article/ae792e13db574342bb09621ee6ec8be6
Autor:
Lisann Pelzl, Zohreh Hosseinzadeh, Tamer al-Maghout, Yogesh Singh, Itishri Sahu, Rosi Bissinger, Sebastian Schmidt, Saad Alkahtani, Christos Stournaras, Mahmoud Toulany, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 3, Pp 1240-1251 (2017)
Background/Aims: Alterations of cytosolic Ca2+-activity ([Ca2+]i) are decisive in the regulation of tumor cell proliferation, migration and survival. Transport processes participating in the regulation of [Ca2+]i include Ca2+ extrusion through K+-ind
Externí odkaz:
https://doaj.org/article/b43c7e2a6d6f481ba115b5e97d9db933
Autor:
Matias Julian Stagno, Nefeli Zacharopoulou, Jonas Bochem, Anna Tsapara, Lisann Pelzl, Tamer al-Maghout, Galatea Kallergi, Saad Alkahtani, Konstantinos Alevizopoulos, Konstantinos Dimas, Theodora Calogeropoulou, Steven W. Warmann, Florian Lang, Evi Schmid, Christos Stournaras
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 4, Pp 1366-1376 (2017)
Background/Aims: Istaroxime is a validated inotropic Na+/K+ ATPase inhibitor currently in development for the treatment of various cardiac conditions. Recent findings established that this steroidal drug exhibits potent apoptotic responses in prostat
Externí odkaz:
https://doaj.org/article/22e8bd753f2b4fe7958893ca236fe546
Autor:
Shaqiu Zhang, Tamer Al-Maghout, Hang Cao, Lisann Pelzl, Madhuri S. Salker, Marc Veldhoen, Anchun Cheng, Florian Lang, Yogesh Singh
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The gut microbiota influences several biological functions including immune responses. Inflammatory bowel disease is favorably influenced by consumption of several dietary natural plant products such as pomegranate, walnuts, and berries containing po
Externí odkaz:
https://doaj.org/article/3c20e53d52954590b1dbea10c3d984df
Autor:
Shaqiu Zhang, Tamer al-Maghout, Yuetao Zhou, Rosi Bissinger, Abeer Abousaab, Madhuri S. Salker, Lisann Pelzl, Bradley S. Cobb, Anchun Cheng, Yogesh Singh, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 4, Pp 1360-1368 (2016)
Background/Aims: Activation of T cell receptors (TCRs) in CD4+ T cells leads to a cascade of signalling reactions including increase of intracellular calcium (Ca2+) levels with subsequent Ca2+ dependent stimulation of gene expression, proliferation,
Externí odkaz:
https://doaj.org/article/fa9d2cfa201b4d2988dd931a09978598
Autor:
Lisann Pelzl, Zohreh Hosseinzadeh, Kousi Alzoubi, Tamer Al-Maghout, Sebastian Schmidt, Christos Stournaras, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 5, Pp 1857-1868 (2015)
Background/Aims: According to previous observations, enhanced store-operated Ca2+-entry (SOCE) accomplished by the pore forming ion channel unit Orai1 and its regulator STIM1 contribute to therapy resistance of ovary carcinoma cells. Ca2+ signaling i
Externí odkaz:
https://doaj.org/article/a099ddcb9a0148cfb9e1748b58dec843
Autor:
Hang Cao, Florian Lang, Jakob Voelkl, Ioana Alesutan, Ke Ma, Tamer Al-Maghout, Burkert Pieske, Ping Liu, Basma Sukkar
Publikováno v:
Journal of Molecular Medicine. 97:1465-1475
Compromised renal phosphate elimination in chronic kidney disease (CKD) leads to hyperphosphatemia, which in turn triggers osteo-/chondrogenic signaling in vascular smooth muscle cells (VSMCs) and vascular calcification. Osteo-/chondrogenic transdiff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::236fb725efb15e7f3158940a7ca68249
https://doi.org/10.1007/s00109-019-01824-7
https://doi.org/10.1007/s00109-019-01824-7
Autor:
Kamal I. Abdel-Fattah, Nagwa H. A. Hassan, Florian Lang, Barbora Droppova, Lisann Pelzl, Khalid N. M. Abdelazeem, Tamer Al-Maghout, Nefeli Zacharopoulou, Christos Stournaras, Basma Sukkar
Publikováno v:
Biochemical and Biophysical Research Communications. 512:467-472
Placental growth factor (PlGF) is produced by tumor cells and stimulates tumor growth and metastasis in part by upregulation of hypoxia inducible factor HIF1α. Orchestration of tumor cell proliferation and migration involves oscillations of cytosoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ae173d8bb2934ee8d72f47d450665be
https://doi.org/10.1016/j.bbrc.2019.03.025
https://doi.org/10.1016/j.bbrc.2019.03.025
Autor:
Lisann Pelzl, Ferruh Artunc, Basma Sukkar, Irene Marini, Abdulla Al Mamun Bhuyan, Burkert Pieske, Jakob Voelkl, David Heinzmann, Itishri Sahu, Flaviana Rigoni, Ke Ma, Hang Cao, Florian Lang, Yamini Sharma, Tamer Al-Maghout, Ravi Kumar Gutti, Tamam Bakchoul, Meinrad Gawaz
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Impairment of renal phosphate elimination in chronic kidney disease (CKD) leads to enhanced plasma and tissue phosphate concentration, which in turn up-regulates transcription factor NFAT5 and serum & glucocorticoid-inducible kinase SGK1. The kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a784e343509c620f619ef6389487033e
https://doi.org/10.1038/s41598-020-58384-x
https://doi.org/10.1038/s41598-020-58384-x