Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Tamer M. Abdelghany"'
Autor:
Hamada A. Mokhlis, Recep Bayraktar, Nashwa N. Kabil, Ayse Caner, Nermin Kahraman, Cristian Rodriguez-Aguayo, Erika P. Zambalde, Jianting Sheng, Kübra Karagoz, Pinar Kanlikilicer, Abdel Aziz H. Abdel Aziz, Tamer M. Abdelghany, Ahmed A. Ashour, Stephen Wong, Michael L. Gatza, George A. Calin, Gabriel Lopez-Berestein, Bulent Ozpolat
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 301-317 (2019)
KRAS is one of the most frequently mutated proto-oncogenes in pancreatic ductal adenocarcinoma (PDAC) and aberrantly activated in triple-negative breast cancer (TNBC). A profound role of microRNAs (miRNAs) in the pathogenesis of human cancer is being
Externí odkaz:
https://doaj.org/article/b75b51d3900244c191dd8e85ccf9ff8e
Autor:
Salwa Elmeligie, Asmaa M. Aboul-Magd, Deena S. Lasheen, Tamer M. Ibrahim, Tamer M. Abdelghany, Sohair M. Khojah, Khaled A. M. Abouzid
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1347-1367 (2019)
In the designed compounds, either a biarylamide or biarylurea moiety or an N-substituted piperazine motif was linked to position 1 of the phthalazine core. The anti-proliferative activity of the synthesised compounds revealed that eight compounds (6b
Externí odkaz:
https://doaj.org/article/9a947ec1fa2c480bb7cdaa3d6abd3640
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1741 (2021)
Critical adverse effects and frequent administration, three times per day, limit the use of flutamide (FLT) as a chemotherapeutic agent in the treatment of prostate cancer. Therefore, our research aimed to develop new cholesterol-based nanovesicles f
Externí odkaz:
https://doaj.org/article/621b646d5c7547c599b4375d12f03a30
Autor:
Hany H. Arab, Samir A. Salama, Tamer M. Abdelghany, Hany A. Omar, El-Shaimaa A. Arafa, Majed M. Alrobaian, Ibrahim A. Maghrabi
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 2, Pp 540-552 (2017)
Background/Aims: Camel milk (CM) has shown beneficial anti-inflammatory actions in several experimental and clinical settings. So far, its effect on rheumatoid arthritis (RA) has not been previously explored. Thus, the current work aimed to evaluate
Externí odkaz:
https://doaj.org/article/2684753bd7494fbf87f5a1c714172934
Autor:
Xiaoping Liu, Mohamed A. El-Mahdy, James Boslett, Saradhadevi Varadharaj, Craig Hemann, Tamer M. Abdelghany, Raed S. Ismail, Sean C. Little, Danlei Zhou, Le Thi Thanh Thuy, Norifumi Kawada, Jay L. Zweier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The gaseous signalling molecule nitric oxide regulates vascular tone. Here, the authors show that nitric oxide is degraded by the enzyme cytoglobin in the vascular wall, and that mice lacking cytoglobin have reduced blood pressure and are less sensit
Externí odkaz:
https://doaj.org/article/7c48b88ebe1f45628a4d604983c1bc11
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 457-467 (2017)
Four series of pyridothienopyrimidin-4-one derivatives were designed and prepared to improve the pim-1 inhibitory activity of the previously reported thieno[2,3-b]pyridines. Significant improvement in the pim-1 inhibition and cytotoxic activity was a
Externí odkaz:
https://doaj.org/article/98e51d7f210c4f7b8b9ea1f284571173
Autor:
Anas Ramadan Kotb, Abdallah E. Abdallah, Hazem Elkady, Ibrahim H. Eissa, Mohammed S. Taghour, Dina Abed Bakhotmah, Tamer M. Abdelghany, Mohamed Ayman El-Zahabi
Publikováno v:
RSC Advances. 13:10488-10502
Novel thalidomide analogs as anticancer immunomodulatory agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0802a2906d6b9ca53d827e7eaf4b6dd3
https://doi.org/10.1039/d3ra00066d
https://doi.org/10.1039/d3ra00066d
Autor:
Mahmoud A. Elrebehy, Tamer M. Abdelghany, Mostafa M. Elshafey, Maher H. Gomaa, Ahmed S. Doghish
Publikováno v:
Pathology - Research and Practice. 247:154557
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2b6d09963d73801fac8f1c159a2bd25
https://doi.org/10.1016/j.prp.2023.154557
https://doi.org/10.1016/j.prp.2023.154557
Autor:
Mohamed G Ewees, Tamer M. Abdelghany, Amgad I. Alkorashy, Ahmed S. Doghish, Walid F. Elkhatib, Ahmed I. Abulsoud, Mostafa M. Elshafey
Publikováno v:
Genomics. 112:3518-3524
Scopoletin is a botanical coumarin. Notably, scopoletin effect on phagocytic activity has not been addressed on transcriptomic level. Accordingly, this study investigated the effect of scopoletin on phagocytosis-linked gene transcription. Whole phago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff839e0a869107b2cc775569746a17f
https://doi.org/10.1016/j.ygeno.2020.03.022
https://doi.org/10.1016/j.ygeno.2020.03.022
Publikováno v:
Bioorganic Chemistry. 86:80-96
Motivated by the potential anticancer activity of both coumarin and 2-aminothiazole nuclei, a new set of thiazol-2-yl hydrazono-chromen-2-one analogs were efficiently synthesized aiming to obtain novel hybrids with potential cytotoxic activity. MTT a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7990a2d7e69b8c4cfc01c434891822bf
https://doi.org/10.1016/j.bioorg.2019.01.026
https://doi.org/10.1016/j.bioorg.2019.01.026