Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Tamer M, Ibrahim"'
Autor:
Mounir A. A. Mohamed, Asmaa M. Kadry, Salma A. Bekhit, Mohammed A. S. Abourehab, Kikuko Amagase, Tamer M. Ibrahim, Ahmed M. M. El-Saghier, Adnan A. Bekhit
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 330-342 (2023)
New spiro-piperidine derivatives were synthesised via the eco-friendly ionic liquids in a one-pot fashion. The in vitro antileishmanial activity against Leishmania major promastigote and amastigote forms highlighted promising antileishmanial activity
Externí odkaz:
https://doaj.org/article/3361f7177b13486f9524e0a4b7c66cd9
Autor:
Mostafa M. M. El-Miligy, Marwa E. Abdelaziz, Salwa M. Fahmy, Tamer M. Ibrahim, Marwa M. Abu-Serie, Mona A. Mahran, Aly A. Hazzaa
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
New quinoline-pyridine hybrids were designed and synthesised as PIM-1/2 kinase inhibitors. Compounds 5b, 5c, 6e, 13a, 13c, and 14a showed in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer ac
Externí odkaz:
https://doaj.org/article/9e34b94d9a5b4637adf59e548997a9d7
Autor:
Manal Abouelwafa, Tamer M. Ibrahim, Mohamed S. El-Hadidi, Mater H. Mahnashi, Amani Y. Owaidah, Nizar H. Saeedi, Hany G. Attia, John J. Georrge, Amany Mostafa
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Oral cancer is one of the most common cancer types. Many factors can express certain genes that cause the proliferation of oral tissues. Overexpressed genes were detected in oral cancer patients; three were highly impacted. FAP, FN1, and MMP1 were th
Externí odkaz:
https://doaj.org/article/e06ce2abad324f5f9eeda80cd0778738
Autor:
Souraya A. Domiati, Khaled H. Abd El Galil, Mohammed A. S. Abourehab, Tamer M. Ibrahim, Hanan M. Ragab
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2179-2190 (2022)
A structure-guided modelling approach using COX-2 as a template was used to investigate the effect of replacing the chloro atom located at the chlorophenyl ring of amide-linked bipyrazole moieties, aiming at attaining better anti-inflammatory effect
Externí odkaz:
https://doaj.org/article/0059908b01c2425ca1e9b5923f422ca4
Autor:
Adnan A. Bekhit, Eskedar T. Lodebo, Ariaya Hymete, Hanan M. Ragab, Salma A. Bekhit, Kikuko Amagase, Afnan Batubara, Mohammed A. S. Abourehab, Alaa El-Din A. Bekhit, Tamer M. Ibrahim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2320-2333 (2022)
Promising inhibitory activities of the parasite multiplication were obtained upon evaluation of in vivo antimalarial activities of new pyrazolylpyrazoline derivatives against Plasmodium berghei infected mice. Further evaluation of 5b and 6a against c
Externí odkaz:
https://doaj.org/article/c2480f42d54a4089bc0c1c71eabf297c
Autor:
Mahmoud A. El Hassab, Tamer M. Ibrahim, Sara T. Al-Rashood, Amal Alharbi, Razan O. Eskandrani, Wagdy M. Eldehna
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 727-736 (2021)
The novel coronavirus disease COVID-19, caused by the virus SARS CoV-2, has exerted a significant unprecedented economic and medical crisis, in addition to its impact on the daily life and health care systems all over the world. Regrettably, no vacci
Externí odkaz:
https://doaj.org/article/98234b16b4e14c1eaae68e930447cbd7
Autor:
Heba H. A. Hassan, Muhammad I. Ismail, Mohammed A. S. Abourehab, Frank M. Boeckler, Tamer M. Ibrahim, Reem K. Arafa
Publikováno v:
Molecules, Vol 28, Iss 3, p 1296 (2023)
Fascin is an actin-bundling protein overexpressed in various invasive metastatic carcinomas through promoting cell migration and invasion. Therefore, blocking Fascin binding sites is considered a vital target for antimetastatic drugs. This inspired u
Externí odkaz:
https://doaj.org/article/250b1a3853dd4315900044dce54e6223
Autor:
Salwa Elmeligie, Asmaa M. Aboul-Magd, Deena S. Lasheen, Tamer M. Ibrahim, Tamer M. Abdelghany, Sohair M. Khojah, Khaled A. M. Abouzid
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1347-1367 (2019)
In the designed compounds, either a biarylamide or biarylurea moiety or an N-substituted piperazine motif was linked to position 1 of the phthalazine core. The anti-proliferative activity of the synthesised compounds revealed that eight compounds (6b
Externí odkaz:
https://doaj.org/article/9a947ec1fa2c480bb7cdaa3d6abd3640
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The coronavirus disease 19 (COVID-19) is a rapidly growing pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its papain-like protease (SARS-CoV-2 PLpro) is a crucial target to halt virus replication. SARS-CoV PLpro
Externí odkaz:
https://doaj.org/article/76eb038cfc314617842c78c32b022d99
Autor:
Mounir A A, Mohamed, Asmaa M, Kadry, Salma A, Bekhit, Mohammed A S, Abourehab, Kikuko, Amagase, Tamer M, Ibrahim, Ahmed M M, El-Saghier, Adnan A, Bekhit
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 38(1)
New spiro-piperidine derivatives were synthesised via the eco-friendly ionic liquids in a one-pot fashion. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b76d899c41e34d90958edac4b1030d24
https://pubmed.ncbi.nlm.nih.gov/36444862
https://pubmed.ncbi.nlm.nih.gov/36444862