Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tamer Eris"'
Autor:
Xiaoyan Guan, Tamer Eris, Le Zhang, Da Ren, Margaret S. Ricci, Tiffany Thiel, Chetan T. Goudar
Publikováno v:
Analytical biochemistry. 643
During the manufacturing of therapeutic proteins, Critical Quality Attributes (CQAs) have been monitored by conventional methods, such as cation exchange chromatography (CEX), reduced capillary electrophoresis-sodium dodecyl sulfate (rCE-SDS), and 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71779c3103e636fe54c99e4c1352a662
https://pubmed.ncbi.nlm.nih.gov/35085546
https://pubmed.ncbi.nlm.nih.gov/35085546
Publikováno v:
Analytical Chemistry. 89:3562-3567
A significant challenge of traditional glycan mapping techniques is that they do not provide site-specific glycosylation information. Therefore, for proteins containing multiple glycosylation sites, the individual glycan species present at a particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd6bc0bcacb5270550a8a70ffaf83c0
https://doi.org/10.1021/acs.analchem.6b04856
https://doi.org/10.1021/acs.analchem.6b04856
Publikováno v:
Biodrugs
Background ABP 501 is being developed as a biosimilar to adalimumab. Comprehensive comparative analytical characterization studies have been conducted and completed. Objective The objective of this study was to assess analytical similarity between AB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9592eaf4a231f7671418ceea5d346985
https://pubmed.ncbi.nlm.nih.gov/27461107
https://pubmed.ncbi.nlm.nih.gov/27461107
Autor:
Yijia Jiang, Ranjini Ramachander, Meagan Young, Mariana Dimitrova, Tamer Eris, Cynthia Li, Linda O. Narhi
Publikováno v:
Analytical Biochemistry. 376:173-182
Fluorescence spectroscopy has been used to measure changes in the tertiary structure of proteins in the solution state. The sensitivity of fluorescence to the protein tryptophan environment has made it a useful tool for studying protein conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1187ad8560b8f22db882336228945d0f
https://doi.org/10.1016/j.ab.2008.02.008
https://doi.org/10.1016/j.ab.2008.02.008
Autor:
Tamer Eris, Jennifer Liu, Viswanatham Katta, Keith R. Westcott, Linda O. Narhi, Kan V. Lu, Hsieng Sen Lu
Publikováno v:
Pharmaceutical Research. 15:632-640
Purpose. To investigate the role and importance of the four methionines in recombinant human leptin, and the effect of methionine oxidation in leptin structural stability and biological activity. Methods. Oxidized leptin derivatives were prepared in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19c4cdb4604f7c76c03f43fed9f5d6b0
https://doi.org/10.1023/a:1011998331254
https://doi.org/10.1023/a:1011998331254
Autor:
Tamer Eris, Zac Yates, Weichun Wang, Robert W. Hong, Gerd R. Kleemann, Jennifer Liu, Boxu Yan, Sean Steen
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 877(16-17)
It has been well documented that papain cleaves an IgG1 molecule to release Fab and Fc domains; however, papain was found unable to release such domains from an IgG2. Here we present a new combinatory strategy to analyze the heterogeneity of the ligh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ac65fa7ed1f6b1f51069d9c2c672ac
https://pubmed.ncbi.nlm.nih.gov/19411197
https://pubmed.ncbi.nlm.nih.gov/19411197
Publikováno v:
The Journal of biological chemistry. 279(16)
N-Linked glycosylation is a post-translational event whereby carbohydrates are added to secreted proteins at the consensus sequence Asn-Xaa-Ser/Thr, where Xaa is any amino acid except proline. Some consensus sequences in secreted proteins are not gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294469e3023c1587593127f5ca9649ed
https://pubmed.ncbi.nlm.nih.gov/14757769
https://pubmed.ncbi.nlm.nih.gov/14757769
Publisher Summary Recombinant human leptin has been recently cloned and expressed in E. coli, and it effectively demonstrates adiposity in mice through modulation of appetite and metabolism. The molecule contains four methionine residues at positions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7807321bd484b65d52933ed516a48202
https://doi.org/10.1016/s1080-8914(97)80018-x
https://doi.org/10.1016/s1080-8914(97)80018-x
