Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tamer A. Elwaie"'
Autor:
Walaa A. Bedewy, Mosaad S. Mohamed, Ahmed M. Abdelhameed, Mohamed A. Elsawy, Mohammed Al-Muhur, Noriyuki Ashida, Ashraf N Abdalla, Tamer A. Elwaie, Tomohisa Nagamatsu, Hamed I. Ali
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Novel 5-deazaflavins were designed as potential anticancer candidates. Compounds 4j, 4k, 5b, 5i, and 9f demonstrated high cytotoxicity against MCF-7 cell line with IC50 of 0.5–190nM. Compounds 8c and 9g showed preferential activity against Hela cel
Externí odkaz:
https://doaj.org/article/3ccb7b98f09f4334a648b495c54b1ef0
Autor:
Walaa A. Bedewy, Mosaad S. Mohamed, Ahmed Abdelhameed, Mohamed A. Elsawy, Mohammed Al-Muhur, Noriyuki Ashida, Ashraf N. Abdalla, Tamer A. Elwaie, Tomohisa Nagamatsu, Hamed I. Ali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2722e35b1acb5ab4b58f0adaf051b4f
https://doi.org/10.2139/ssrn.4423116
https://doi.org/10.2139/ssrn.4423116
Autor:
Hamed I. Ali, Tamer A Elwaie, Safinaz E. Abbas, Enayat I. Aly, Khalid A. El Sayed, Zakaria Y. Abd Elmageed, Hamdy E. A. Ali, Nikolai Kraiouchkine, Riham F. George, Tamer E. Fandy, Khaldoun S. Abdelwahed
Publikováno v:
Journal of Medicinal Chemistry. 63:15906-15945
HER2 kinase as a well-established target for breast cancer (BC) therapy is associated with aggressive clinical outcomes; thus, herein we present structural optimization for HER2-selective targeting. HER2 profiling of the developed derivatives demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39895f810789a244dde3181af7d16777
https://doi.org/10.1021/acs.jmedchem.0c01647
https://doi.org/10.1021/acs.jmedchem.0c01647