Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Tame CJ"'
1
Akademický článek
Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs.
Autor: Law RP; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Nunes J; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Chung CW; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Bantscheff M; Cellzome GmbH, a GSK company, Meyerhofstraße 1, 69117, Heidelberg, Germany., Buda K; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Dai H; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Evans JP; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Flinders A; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Klimaszewska D; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Lewis AJ; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Muelbaier M; Cellzome GmbH, a GSK company, Meyerhofstraße 1, 69117, Heidelberg, Germany., Scott-Stevens P; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Stacey P; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Tame CJ; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Watt GF; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Zinn N; Cellzome GmbH, a GSK company, Meyerhofstraße 1, 69117, Heidelberg, Germany., Queisser MA; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Harling JD; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Benowitz AB; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Oct 18; Vol. 60 (43), pp. 23327-23334. Date of Electronic Publication: 2021 Sep 17.
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2
Akademický článek
Structural Insights into PROTAC-Mediated Degradation of Bcl-xL.
Autor: Chung CW; Protein, Cellular & Structural Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Dai H; Protein Degradation Group, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Fernandez E; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Tinworth CP; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Churcher I; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Cryan J; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Denyer J; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Harling JD; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Konopacka A; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Queisser MA; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Tame CJ; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Watt G; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom., Jiang F; Viva Biotech, Ltd., 334 Aidisheng Rd., Zhangjiang High-tech Park, Shanghai 201203, China., Qian D; Viva Biotech, Ltd., 334 Aidisheng Rd., Zhangjiang High-tech Park, Shanghai 201203, China., Benowitz AB; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Publikováno v: ACS chemical biology [ACS Chem Biol] 2020 Sep 18; Vol. 15 (9), pp. 2316-2323. Date of Electronic Publication: 2020 Aug 13.
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3
Akademický článek
Rhodium-catalysed vinyl 1,4-conjugate addition coupled with Sharpless asymmetric dihydroxylation in the synthesis of the CDE ring fragment of pectenotoxin-4.
Autor: Richardson MSW; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email: timothy.donohoe@chem.ox.ac.uk., Tame CJ; GlaxoSmithKline Medicines Research Centre , Gunnels Wood Road , Stevenage , SG1 2NY , UK., Poole DL; GlaxoSmithKline Medicines Research Centre , Gunnels Wood Road , Stevenage , SG1 2NY , UK., Donohoe TJ; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , Mansfield Road , Oxford , OX1 3TA , UK . Email: timothy.donohoe@chem.ox.ac.uk.
Publikováno v: Chemical science [Chem Sci] 2019 May 24; Vol. 10 (25), pp. 6336-6340. Date of Electronic Publication: 2019 May 24 (Print Publication: 2019).
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4
Akademický článek
Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
Autor: Amour A, Barton N, Cooper AW, Inglis G, Jamieson C, Luscombe CN, Morrell J, Peace S, Perez D, Rowland P, Tame CJ, Uddin S, Vitulli G, Wellaway N
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2016 Oct 27; Vol. 59 (20), pp. 9574. Date of Electronic Publication: 2016 Oct 11.
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5
Akademický článek
Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
Autor: Amour A, Barton N, Cooper AW, Inglis G, Jamieson C, Luscombe CN, Morrell J, Peace S, Perez D, Rowland P, Tame CJ, Uddin S, Vitulli G, Wellaway N
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2016 Sep 08; Vol. 59 (17), pp. 8148. Date of Electronic Publication: 2016 Aug 22.
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6
Akademický článek
Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
Autor: Amour A; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Barton N; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Cooper AW; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Inglis G; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Jamieson C; Department of Pure and Applied Chemistry, University of Strathclyde , 295 Cathedral Street, Glasgow G1 1XL, U.K., Luscombe CN; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Morrell J; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Peace S; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Perez D; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Rowland P; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Tame CJ; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Uddin S; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Vitulli G; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K., Wellaway N; GlaxoSmithKline R&D , Gunnels Wood Road, Stevenage SG1 2NY, U.K.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2016 Aug 11; Vol. 59 (15), pp. 7239-51. Date of Electronic Publication: 2016 Jul 27.
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7
Akademický článek
Sustainable Synthesis of Chiral Tetrahydrofurans through the Selective Dehydration of Pentoses.
Autor: Foster RW; Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ (UK) http://www.tomsheppard.eu., Tame CJ; GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage, Herts, SG1 2NY (UK)., Bučar DK; Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ (UK) http://www.tomsheppard.eu., Hailes HC; Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ (UK) http://www.tomsheppard.eu. h.c.hailes@ucl.ac.uk., Sheppard TD; Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ (UK) http://www.tomsheppard.eu. tom.sheppard@chem.ucl.ac.uk.
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2015 Nov 02; Vol. 21 (45), pp. 15947-50. Date of Electronic Publication: 2015 Sep 25.
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8
Akademický článek
Irreversible endo-selective diels-alder reactions of substituted alkoxyfurans: a general synthesis of endo-cantharimides.
Autor: Foster RW; Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ (UK)., Benhamou L, Porter MJ, Bučar DK, Hailes HC, Tame CJ, Sheppard TD
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2015 Apr 13; Vol. 21 (16), pp. 6107-14. Date of Electronic Publication: 2015 Mar 10.
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9
Akademický článek
Gold catalysed synthesis of 3-alkoxyfurans at room temperature.
Autor: Pennell MN; Department of Chemistry, University College London, 20 Gordon St, London, WC1H 0AJ, UK. tom.sheppard@ucl.ac.uk., Foster RW, Turner PG, Hailes HC, Tame CJ, Sheppard TD
Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2014 Feb 09; Vol. 50 (11), pp. 1302-4.
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10
Akademický článek
Highly Regioselective Synthesis of Substituted Isoindolinones via Ruthenium-Catalyzed Alkyne Cyclotrimerizations.
Autor: Foster RW; Department of Chemistry, University College London, Christopher Ingold Laboratories London, WC1H 0AJ, U.K. ; phone: (+44)-(0)20-7679-2467., Tame CJ, Hailes HC, Sheppard TD
Publikováno v: Advanced synthesis & catalysis [Adv Synth Catal] 2013 Aug 12; Vol. 355 (11-12), pp. 2353-2360.
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