Many faces of mitochondrial uncoupling during age: damage or defense?

Autor: Bellanti F, Romano AD, Rollo T, Blonda M, Tamborra R, Vendemiale G, Serviddio G., GIUDETTI, Anna Maria

An increased mitochondrial proton leak occurs in aging, but the origin of such modification remains unclear. This study defined the cause of mitochondrial uncoupling in mitotic (liver) and postmitotic (heart) rat tissues during aging and its effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4034::1e3d253ddb96b70ee944cefd7ba1e042
https://hdl.handle.net/11587/381093

A silybin-phospholipid complex prevents mitochondrial dysfunction in a rodent model of nonalcoholic steatohepatitis

Autor: Serviddio G, Bellanti F, Petrella A, Tamborra R, Romano AD, Rollo T, Vendemiale G, Altomare E., GIUDETTI, Anna Maria, GNONI, Gabriele Vincenzo

Mitochondrial dysfunction and oxidative stress are determinant events in the pathogenesis of nonalcoholic steatohepatitis. Silybin has shown antioxidant, anti-inflammatory, and antifibrotic effects in chronic liver disease. We aimed to study the effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4034::9ceec5bdd08efecb564c778959cae00b
https://hdl.handle.net/11587/338102

MITOCHONDRIAL DYSFUNCTIONS IN A TRANSGENIC MURINE MODEL OF ALZHEIMER’S DISEASE

Autor: Cassano, T., Serviddio, G., Bellanti, F., Tamborra, R., Macheda, T., Morgese, M. G., Trabace, L., Oddo, S., Laferla, F. M., Cuomo, Vincenzo, Vendemiale, G.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3686::93c7d5ea5e8c43cc99ad36cc3fd66ac3
http://hdl.handle.net/11573/472998

Pathological mutations of the human NDUFS4 gene of the 18 k-Da (AQDQ) subunitof complex I: effect on the protein expression and on complex assembly and function

Autor: Petruzzella V., Scacco S., Budde S., Vergari R., Tamborra R., Panelli D., Van den Heuvel L.P., Smeitink J.A., Papa S.

Publikováno v: 48° Congresso Nazionale SIB 15-18 Settembre, Ferrara, 2003
info:cnr-pdr/source/autori:. Petruzzella V., Scacco S., Budde S., Vergari R., Tamborra R., Panelli D., Van den Heuvel L.P., Smeitink J.A., Papa S./congresso_nome:48° Congresso Nazionale SIB 15-18 Settembre/congresso_luogo:Ferrara/congresso_data:2003/anno:2003/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::71ea01ea371a66f5a9b1fc2d38a41b32
http://www.cnr.it/prodotto/i/103419

Pathological mutations of the human NDUFS4 gene of the 18-kDa (AQDQ) subunit of complex I affect the expression of the protein and the assembly and function of the complex

Autor: Scacco S 1, Petruzzella V 1, Budde S 2, Vergari R 1, Tamborra R 1, Panelli D 1, van den Heuvel LP 2, Smeitink JA 2, Papa S 1

Publikováno v: 278 (2003): 44161–44167.
info:cnr-pdr/source/autori:Scacco S 1, Petruzzella V 1, Budde S 2, Vergari R 1, Tamborra R 1, Panelli D 1, van den Heuvel LP 2, Smeitink JA 2, Papa S 1,3./titolo:Pathological mutations of the human NDUFS4 gene of the 18-kDa (AQDQ) subunit of complex I affect the expression of the protein and the assembly and function of the complex./doi:/rivista:/anno:2003/pagina_da:44161/pagina_a:44167/intervallo_pagine:44161–44167/volume:278

Presented is a study of the impact on the structure and function of human complex I of three different homozygous mutations in the NDUFS4 gene coding for the 18-kDa subunit of respiratory complex I, inherited by autosomal recessive mode in three chil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::3f6652f48adf911a5e66a575af29c563
http://www.cnr.it/prodotto/i/12693