Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Tamayo Uechi"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Mitochondrial and lysosomal dysfunction are central to Parkinson’s disease (PD) pathogenesis. Here, the authors show mitochondrial dsDNA in the cytosol in cellular and Zebrafish models of PD induces cytotoxicity and neurodegeneration; knock-down of
Externí odkaz:
https://doaj.org/article/a628dfb33fe649838ef8fb28d3fa0336
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Objectives Cell-culture studies reported that prokaryotic RNA molecules among the various microbe-associated molecular patterns (MAMPs) were uniquely present in live bacteria and were categorized as viability-associated MAMPs. They also repo
Externí odkaz:
https://doaj.org/article/e6a4b058eb10495d970b2130732b0307
Autor:
Mary McMahon, Adrian Contreras, Mikael Holm, Tamayo Uechi, Craig M Forester, Xiaming Pang, Cody Jackson, Meredith E Calvert, Bin Chen, David A Quigley, John M Luk, R Kate Kelley, John D Gordan, Ryan M Gill, Scott C Blanchard, Davide Ruggero
Publikováno v:
eLife, Vol 8 (2019)
Small nucleolar RNAs (snoRNAs) are a diverse group of non-coding RNAs that direct chemical modifications at specific residues on other RNA molecules, primarily on ribosomal RNA (rRNA). SnoRNAs are altered in several cancers; however, their role in ce
Externí odkaz:
https://doaj.org/article/049984ff3ff540b49c64893eccc6ff9f
Autor:
Fumika Ikeda, Kenichi Yoshida, Tsutomu Toki, Tamayo Uechi, Shiori Ishida, Yukari Nakajima, Yoji Sasahara, Yusuke Okuno, Rika Kanezaki, Kiminori Terui, Takuya Kamio, Akie Kobayashi, Takashi Fujita, Aiko Sato-Otsubo, Yuichi Shiraishi, Hiroko Tanaka, Kenichi Chiba, Hideki Muramatsu, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Naoya Kenmochi, Satoru Miyano, Seishi Ogawa, Etsuro Ito
Publikováno v:
Haematologica, Vol 102, Iss 3 (2017)
Externí odkaz:
https://doaj.org/article/a485bf39c5f146ff99328293b9118aea
Autor:
Tamayo Uechi, Naoya Kenmochi
Publikováno v:
Pharmaceuticals, Vol 12, Iss 4, p 151 (2019)
Diamond-Blackfan anemia (DBA) is a rare bone marrow failure syndrome characterized by red blood cell aplasia. Currently, mutations in 19 ribosomal protein genes have been identified in patients. However, the pathogenic mechanism of DBA remains unknow
Externí odkaz:
https://doaj.org/article/9468a91db49d447889a4eb0adbd87b49
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4152 (2009)
Ribosome is responsible for protein synthesis in all organisms and ribosomal proteins (RPs) play important roles in the formation of a functional ribosome. L11 was recently shown to regulate p53 activity through a direct binding with MDM2 and abrogat
Externí odkaz:
https://doaj.org/article/1783450699474cd9a38d86b686761739
Autor:
Tamayo Uechi, Yukari Nakajima, Akihiro Nakao, Hidetsugu Torihara, Anirban Chakraborty, Kunio Inoue, Naoya Kenmochi
Publikováno v:
PLoS ONE, Vol 1, p e37 (2006)
The ribosomal proteins (RPs) form the majority of cellular proteins and are mandatory for cellular growth. RP genes have been linked, either directly or indirectly, to various diseases in humans. Mutations in RP genes are also associated with tissue-
Externí odkaz:
https://doaj.org/article/89b6f9fe14f34f8bb1d8525436b6b71f
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
BMC Research Notes
BMC Research Notes
Objectives Cell-culture studies reported that prokaryotic RNA molecules among the various microbe-associated molecular patterns (MAMPs) were uniquely present in live bacteria and were categorized as viability-associated MAMPs. They also reported that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba28bd6435a814250211109e29d098c5
https://doaj.org/article/e6a4b058eb10495d970b2130732b0307
https://doaj.org/article/e6a4b058eb10495d970b2130732b0307
Autor:
Naoya Kenmochi, Kunwadee Palasin, Maki Yoshihama, Naparee Srisowanna, Yoshitaka Hishikawa, Narantsog Choijookhuu, Wilaiwan Chotigeat, Tamayo Uechi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
In this study, to investigate the secondary function of Rpl10a in zebrafish development, morpholino antisense oligonucleotides (MOs) were used to knock down the zebrafish ribosomal protein L10a (rpl10a). At 25 hpf (hours post-fertilization), embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7ce276092af66d25bdc4da08492ef6
http://europepmc.org/articles/PMC6889351
http://europepmc.org/articles/PMC6889351
Autor:
Kenichi Chiba, Etsuro Ito, Seiji Kojima, Akie Kobayashi, Shiori Ishida, Shouichi Ohga, Naoya Kenmochi, Akira Ohara, Satoru Miyano, Fumika Ikeda, Kenichi Yoshida, Hiroko Tanaka, Yoji Sasahara, Kiminori Terui, Takashi Fujita, Tamayo Uechi, Yusuke Okuno, Yukari Nakajima, Aiko Sato-Otsubo, Tsutomu Toki, Takuya Kamio, Rika Kanezaki, Hitoshi Kanno, Yuichi Shiraishi, Hideki Muramatsu, Seishi Ogawa
Publikováno v:
HAEMATOLOGICA. 102(3):E93-E96
Diamond-Blackfan anemia (DBA) is a congenital bone marrow failure syndrome, characterized by red blood cell aplasia, macrocytic anemia, variable malformations, and increased risk of malignancy.[1][1]–[3][2] DBA has been associated with heterozygous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9be9f8bb6106461dfc387d96ea47573
https://hirosaki.repo.nii.ac.jp/records/5453
https://hirosaki.repo.nii.ac.jp/records/5453