Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tamas Kriska"'
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 615-624 (2018)
Polarization of macrophages to proinflammatory M1 and to antiinflammatory alternatively activated M2 states has physiological implications in the development of experimental hypertension and other pathological conditions. 12/15-Lipoxygenase (12/15-LO
Externí odkaz:
https://doaj.org/article/5457e9c1716b4d4eb9fdb5d09d1751f0
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 11, Pp 3174-3184 (2010)
Sterol carrier protein-2 (SCP-2) plays an important role in cholesterol trafficking and metabolism in mammalian cells. The purpose of this study was to determine whether SCP-2, under oxidative stress conditions, might also traffic hydroperoxides of c
Externí odkaz:
https://doaj.org/article/b4f2b87bb5234ab08e0145b940250a55
Autor:
William B. Campbell, Adeniyi Michael Adebesin, Anja Herrnreiter, John R. Falck, Tamas Kriska, Sandra L. Pfister
Publikováno v:
Hypertension. 79:104-114
12/15-LO (12/15-lipoxygenase), encoded by Alox15 gene, metabolizes arachidonic acid to 12(S)-HETE (12-hydroxyeicosatetraenoic acid). Macrophages are the major source of 12/15-LO among immune cells, and 12/15-LO plays a crucial role in development of
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 615-624 (2018)
Polarization of macrophages to proinflammatory M1 and to antiinflammatory alternatively activated M2 states has physiological implications in the development of experimental hypertension and other pathological conditions. 12/15-Lipoxygenase (12/15-LO
Publikováno v:
Endocrinology. 159:217-226
Angiotensin II (Ang II) and adrenocorticotropic hormone (ACTH) regulate adrenal vascular tone in vitro through endothelial and zona glomerulosa cell–derived mediators. The role of these mediators in regulating adrenal blood flow (ABF) and mean arte
Autor:
Kathryn M. Gauthier, Daniel Goldman, Lawan Siangjong, John R. Falck, Ganesh Kumar, Narender Puli, William B. Campbell, Tamas Kriska, Emer M. Smyth
Publikováno v:
Acta Physiologica. 219:188-201
Aim 12/15-lipoxygenase (12/15-LO) metabolizes arachidonic acid (AA) into several vasoactive eicosanoids. In mouse arteries, we previously characterized the enzyme's 15-LO metabolites 12(S)-hydroxyeicosatetraenoic acid (HETE), 15-HETE, hydroxyepoxyeic
Autor:
Cody Cepura, Tamas Kriska, Tina C. Wan, A. Shaish, John A. Auchampach, Lawan Siangjong, John R. Falck, Kathryn M. Gauthier, William B. Campbell, Ganesh Kumar, Dror Haratz
Publikováno v:
Prostaglandins & Other Lipid Mediators. 106:8-15
Lipoxygenases regulate vascular function by metabolizing arachidonic acid (AA) to dilator eicosanoids. Previously, we showed that endothelium-targeted adenoviral vector-mediated gene transfer of the human 15-lipoxygenase-1 (h15-LO-1) enhances arteria
Publikováno v:
Free Radical Biology and Medicine. 45:700-707
A novel approach for selecting high expressing cells out of a general population that had been transfected with a construct encoding cytosolic type 4 glutathione peroxidase (GPx4) is reported. The approach is described for GPx4-null COH-BR1 breast tu
Autor:
Friedhelm Schroeder, Vladislav Levchenko, Witold Korytowski, Barbara P. Atshaves, Albert W. Girotti, Tamas Kriska
Publikováno v:
Journal of Biological Chemistry. 281:23643-23651
Sterol carrier protein-2 (SCP-2) plays a crucial role in the trafficking and metabolism of cholesterol and other lipids in mammalian cells. Lipid hydroperoxides generated under oxidative stress conditions are relatively long-lived intermediates that
Autor:
Molly C. Semones, Tamas Kriska, Jeffrey M. Grim, Elizabeth L. Crockett, Donald E. Kuhn, Agnes Keszler
Changes in oxidative capacities and phospholipid remodeling accompany temperature acclimation in ectothermic animals. Both responses may alter redox status and membrane susceptibility to lipid peroxidation (LPO). We tested the hypothesis that phospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c3dc4fdd6af8bbe02cd2166c4794ff
https://europepmc.org/articles/PMC4346761/
https://europepmc.org/articles/PMC4346761/