Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Tamas KOVACS"'
Autor:
Tamas Kovacs, Bence Cs. Szabo, Rosemary Chandrakanthi Kothalawala, Virag Szekelyhidi, Peter Nagy, Zoltan Varga, Gyorgy Panyi, Florina Zakany
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The human voltage-gated proton channel (HV1) provides an efficient proton extrusion pathway from the cytoplasm contributing to the intracellular pH regulation and the oxidative burst. Although its pharmacological inhibition was previously shown to in
Externí odkaz:
https://doaj.org/article/7a2fea90d9694416aadc28aa310b2238
Autor:
Bence Cs. Szabo, Mate Szabo, Peter Nagy, Zoltan Varga, Gyorgy Panyi, Tamas Kovacs, Florina Zakany
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 8, Pp 100596- (2024)
Membrane lipids extensively modulate the activation gating of voltage-gated potassium channels (KV), however, much less is known about the mechanisms of ceramide and glucosylceramide actions including which structural element is the main intramolecul
Externí odkaz:
https://doaj.org/article/205b9353af6042a9b865a9ca3229b15f
Autor:
Szilamér Ferenczi, Fruzsina Mogor, Peter Takacs, Tamas Kovacs, Viktoria E. Toth, Zoltán V. Varga, Krisztina Kovács, Zoltan Lohinai, Koppány Csaba Vass, Nandor Nagy, David Dora
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Previously, the presence of a blood-myenteric plexus barrier and its disruption was reported in experimentally induced colitis via a macrophage-dependent process. The aim of this study is to reveal how myenteric barrier disruption and subseq
Externí odkaz:
https://doaj.org/article/886c13f3f37d4de5af40aeac9394aa98
Autor:
David Dora, Balazs Ligeti, Tamas Kovacs, Peter Revisnyei, Gabriella Galffy, Edit Dulka, Dániel Krizsán, Regina Kalcsevszki, Zsolt Megyesfalvi, Balazs Dome, Glen J. Weiss, Zoltan Lohinai
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTDue to the high variance in response rates concerning anti-PD1 immunotherapy (IT), there is an unmet need to discover innovative biomarkers to predict immune checkpoint inhibitor (ICI)-efficacy. Our study included 62 Caucasian advanced-stage
Externí odkaz:
https://doaj.org/article/3192af9b75d0451fa3c5111eb3db9471
Autor:
Geza Makkai, Istvan M. Abraham, Klaudia Barabas, Soma Godo, David Ernszt, Tamas Kovacs, Gergely Kovacs, Szilard Szocs, Tibor Z. Janosi
Publikováno v:
Frontiers in Neuroinformatics, Vol 17 (2023)
The rapid effects of estradiol on membrane receptors are in the focus of the estradiol research field, however, the molecular mechanisms of these non-classical estradiol actions are poorly understood. Since the lateral diffusion of membrane receptors
Externí odkaz:
https://doaj.org/article/e606c1a8cfb243a4b6baa319e17dffbc
Publikováno v:
Cells, Vol 12, Iss 13, p 1700 (2023)
Every cell biological textbook teaches us that the main role of the plasma membrane is to separate cells from their neighborhood to allow for a controlled composition of the intracellular space. The mostly hydrophobic nature of the cell membrane pres
Externí odkaz:
https://doaj.org/article/4405036601e04ffd91fea8a87356a699
Autor:
David Dora, Szilamer Ferenczi, Rhian Stavely, Viktoria E. Toth, Zoltan V. Varga, Tamas Kovacs, Ildiko Bodi, Ryo Hotta, Krisztina J. Kovacs, Allan M. Goldstein, Nandor Nagy
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1617-1641 (2021)
Background & Aims: Neuroinflammation in the gut is associated with many gastrointestinal (GI) diseases, including inflammatory bowel disease. In the brain, neuroinflammatory conditions are associated with blood-brain barrier (BBB) disruption and subs
Externí odkaz:
https://doaj.org/article/b9e37b6203c345f9b54c75273c761468
Autor:
Nikolai Juul, Aurélie Cazals, Aybike Hofmann, Virginia Amesty, Gilvydas Verkauskas, Barbara Dobrowolska-Glazar, Gundela Holmdahl, Maria Escolino, Jacques Birraux, Tamas Kovacs, Nicolas Kalfa, Magdalena Fossum
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
IntroductionCOVID-19 impacted healthcare systems worldwide, and elective surgical activity was brought to a minimum. Although children were not primarily affected by the disease, pediatric urology was halted by clinical closedown and staff allocation
Externí odkaz:
https://doaj.org/article/78a53daff53544aeaa0cd4c0e43493c3
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 6, Iss 3, Pp 326-330 (2020)
Internal jugular venous aneurysm (IJVA) is a rare entity that usually remains asymptomatic with only rare complications. We report two cases of IJVA. Both patients presented with a palpable soft tissue mass in the neck and were found to have IJVA on
Externí odkaz:
https://doaj.org/article/c0b9ca96c2de4785baaa2ee32039f14f
Autor:
Tamas Kovacs, Tamas Sohajda, Lajos Szente, Peter Nagy, Gyorgy Panyi, Zoltan Varga, Florina Zakany
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Cyclodextrins (CDs) are cyclic oligosaccharides capable of forming water-soluble complexes with a variety of otherwise poorly soluble molecules including cholesterol and different drugs. Consistently, CDs are widely used in research and clinical prac
Externí odkaz:
https://doaj.org/article/4110892c186142c0976828cc585642e4