Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tamas Bakos"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115294- (2023)
Background and objective: Cytokine storm (CS) is a major contributor to the fatal outcome of severe infectious diseases, including Covid-19. Treatment with the complement (C) C5 inhibitor eculizumab was beneficial in end-stage Covid-19, however, the
Externí odkaz:
https://doaj.org/article/8ab4e479d9e84d838884f90a060d2c3d
Autor:
Alexander L. Weis, Veena Prasad, I-Tien Yeh, Asok Banerjee, John C. Lee, Richard F. Ludueña, Lee Chuan C Yeh, Tamas Bakos, Jack A. Tuszynski
Publikováno v:
Investigational New Drugs. 34:129-137
The subunit protein of microtubules is tubulin, which has been the target for some of the most successful and widely used anti-tumor drugs. Most of the drugs that target tubulin bind to the β subunit. There are many isotypes of β-tubulin and their
Autor:
Tamás Bakos, Tamás Mészáros, Gergely Tibor Kozma, Petra Berényi, Réka Facskó, Henriette Farkas, László Dézsi, Carlo Heirman, Stefaan de Koker, Raymond Schiffelers, Kathryn Anne Glatter, Tamás Radovits, Gábor Szénási, János Szebeni
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3595 (2024)
A small fraction of people vaccinated with mRNA–lipid nanoparticle (mRNA-LNP)-based COVID-19 vaccines display acute or subacute inflammatory symptoms whose mechanism has not been clarified to date. To better understand the molecular mechanism of th
Externí odkaz:
https://doaj.org/article/69574a4c7729496bba6f9bfd31ae067f
Autor:
John Torin Huzil, Sambasivarao Damaraju, Richard F. Ludueña, Lorelei Johnson, Tamas Bakos, Alexander L. Weis, Asok Banerjee, Jack A. Tuszynski, Philip Winter
Publikováno v:
Chemical Biology & Drug Design. 75:541-550
Microtubules are the primary target for many anti-cancer drugs, the majority of which bind specifically to beta-tubulin. The existence of several beta-tubulin isotypes, coupled with their varied expression in normal and cancerous cells provides a pla
Publikováno v:
Chemical Physics Letters. 414:61-65
Using first-principles density functional theory calculations of chemical reactions between the dominant precursor (the SiH 3 radical) for plasma deposition of hydrogenated amorphous silicon (a-Si:H) thin films and different hydrogen-terminated cryst
Publikováno v:
The Journal of Antibiotics. 48:667-670
20-Homo tylosin, 20-nor tylosin, 20-deoxy-19,20-didehydro tylosin (6-vinyl tylosin) and 2",3"-didehydro-3"-deoxy tylosin were prepared by multi-step procedures. 20-Homo tylosin was about twice less active than tylosin while the other compounds exhibi
Publikováno v:
ChemInform. 30
The synthesis and conversion of a new spermidine equivalent ( 2 ) to squalamine is reported. It is prepared in a practical manner, is stable to sodium borohydride reduction, is converted to spermidine under mild conditions, and is not prone to intern
Autor:
Gábor Kökény, Tamás Bakos, Bálint András Barta, Georgina Viktória Nagy, Tamás Mészáros, Gergely T. Kozma, András Szabó, János Szebeni, Béla Merkely, Tamás Radovits
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1138 (2023)
Hemodynamic disturbance, a rise in neutrophil-to-lymphocyte ratio (NLR) and release of inflammatory cytokines into blood, is a bad prognostic indicator in severe COVID-19 and other diseases involving cytokine storm syndrome (CSS). The purpose of this
Externí odkaz:
https://doaj.org/article/7fc9338eab9f42f5b28dfb3d86327d70
Publikováno v:
Physical Review B. 74
We present a detailed analysis of the fundamental atomic-scale processes that determine the surface smoothness of hydrogenated amorphous silicon (a-Si:H) thin films. The analysis is based on a synergistic combination of molecular-dynamics (MD) simula
Publikováno v:
Physical Review Letters. 95
An important concern in the deposition of thin hydrogenated amorphous silicon () films is to obtain smooth surfaces. Herein, we combine molecular-dynamics simulations with first-principles density functional theory calculations to elucidate the smoot